STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
insJIS150 transposase A; Belongs to the IS150/IS1296 orfA family. (173 aa)    
Predicted Functional Partners:
insK
IS150 transposase B; Involved in the transposition of the insertion sequence IS150; Belongs to the transposase IS3/IS150/IS904 family.
 
  
 0.996
yggC
Putative PanK family P-loop kinase; Putative kinase.
      
 0.788
tap
Methyl-accepting protein IV; Mediates taxis toward dipeptides via an interaction with the periplasmic dipeptide-binding protein.
      
 0.645
insI1
Transposase InsI for insertion sequence element IS30A; Required for the transposition of the insertion element.
     
 0.623
yqeC
Putative selenium-dependent hydroxylase accessory protein.
      
 0.623
insB1-6
IS1 transposase B.
      
 0.623
hokA
Protein HokA; Toxic component of a type I toxin-antitoxin (TA) system (Probable). When overexpressed kills cells within minutes; causes collapse of the transmembrane potential and arrest of respiration. Its toxic effect is probably neutralized by antisense antitoxin RNA SokA. Belongs to the Hok/Gef family.
       0.552
yhhA
DUF2756 family protein.
      
 0.544
mpaA
Murein peptide amidase A; Involved in muropeptide degradation. Catalyzes the hydrolysis of the gamma-D-glutamyl-diaminopimelic acid (gamma-D-Glu-Dap) amide bond in the murein tripeptide L-alanyl-gamma-D-glutamyl-meso- diaminopimelic acid, leading to the formation of L-Ala-gamma-D-Glu and Dap. Has weak activity with L-Ala- gamma-D-Glu-L-Lys, MurNAc-tripeptide and gamma-D-Glu-meso-Dap. Cannot hydrolyze murein tetrapeptide ; Belongs to the peptidase M14 family.
      
 0.543
yhhI
H repeat-associated putative transposase YhhI; Pseudogene fragment; Belongs to the transposase 11 family.
      
 0.530
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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