node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
adeD | amn | b3665 | b1982 | Cryptic adenine deaminase; Protein involved in metabolic process; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. | AMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations. | 0.912 |
adeD | apt | b3665 | b0469 | Cryptic adenine deaminase; Protein involved in metabolic process; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.992 |
adeD | deoD | b3665 | b4384 | Cryptic adenine deaminase; Protein involved in metabolic process; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. | Purine nucleoside phosphorylase 1; Cleavage of guanosine or inosine to respective bases and sugar-1-phosphate molecules. | 0.937 |
adeD | hpt | b3665 | b0125 | Cryptic adenine deaminase; Protein involved in metabolic process; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. | Hypoxanthine phosphoribosyltransferase; Acts preferentially on hypoxanthine; has very low activity towards guanine. Inactive towards xanthine. Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.925 |
adeD | paoA | b3665 | b0286 | Cryptic adenine deaminase; Protein involved in metabolic process; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. | PaoABC aldehyde oxidoreductase, 2Fe-2S subunit; Oxidizes aldehydes to the corresponding carboxylic acids with a preference for aromatic aldehydes. It might play a role in the detoxification of aldehydes to avoid cell damage. | 0.916 |
adeD | paoC | b3665 | b0284 | Cryptic adenine deaminase; Protein involved in metabolic process; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. | PaoABC aldehyde oxidoreductase, Moco-containing subunit; Oxidizes aldehydes to the corresponding carboxylic acids with a preference for aromatic aldehydes. It might play a role in the detoxification of aldehydes to avoid cell damage. Belongs to the xanthine dehydrogenase family. | 0.904 |
adeD | rihB | b3665 | b2162 | Cryptic adenine deaminase; Protein involved in metabolic process; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. | Ribonucleoside hydrolase 2; Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively. Has a clear preference for cytidine over uridine. Strictly specific for ribonucleosides. Has a low but significant activity for the purine nucleoside xanthosine; Belongs to the IUNH family. RihB subfamily. | 0.905 |
adeD | xdhA | b3665 | b2866 | Cryptic adenine deaminase; Protein involved in metabolic process; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. | Xanthine dehydrogenase, molybdenum binding subunit; Presumed to be a dehydrogenase, but possibly an oxidase. Participates in limited purine salvage (requires aspartate) but does not support aerobic growth on purines as the sole carbon source (purine catabolism). Deletion results in increased adenine sensitivity, suggesting that this protein contributes to the conversion of adenine to guanine nucleotides during purine salvage. | 0.942 |
adeD | xdhB | b3665 | b2867 | Cryptic adenine deaminase; Protein involved in metabolic process; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. | Xanthine dehydrogenase, FAD-binding subunit; Presumed to be a dehydrogenase, but possibly an oxidase. Participates in limited purine salvage (requires aspartate) but does not support aerobic growth on purines as the sole carbon source (purine catabolism). | 0.947 |
adeD | xdhC | b3665 | b2868 | Cryptic adenine deaminase; Protein involved in metabolic process; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. | Xanthine dehydrogenase, Fe-S binding subunit; Iron-sulfur subunit of the xanthine dehydrogenase complex. | 0.926 |
amn | adeD | b1982 | b3665 | AMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations. | Cryptic adenine deaminase; Protein involved in metabolic process; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. | 0.912 |
amn | apt | b1982 | b0469 | AMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.914 |
amn | deoD | b1982 | b4384 | AMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations. | Purine nucleoside phosphorylase 1; Cleavage of guanosine or inosine to respective bases and sugar-1-phosphate molecules. | 0.931 |
amn | rihB | b1982 | b2162 | AMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations. | Ribonucleoside hydrolase 2; Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively. Has a clear preference for cytidine over uridine. Strictly specific for ribonucleosides. Has a low but significant activity for the purine nucleoside xanthosine; Belongs to the IUNH family. RihB subfamily. | 0.902 |
apt | adeD | b0469 | b3665 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Cryptic adenine deaminase; Protein involved in metabolic process; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. | 0.992 |
apt | amn | b0469 | b1982 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | AMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations. | 0.914 |
apt | deoD | b0469 | b4384 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Purine nucleoside phosphorylase 1; Cleavage of guanosine or inosine to respective bases and sugar-1-phosphate molecules. | 0.980 |
apt | hpt | b0469 | b0125 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Hypoxanthine phosphoribosyltransferase; Acts preferentially on hypoxanthine; has very low activity towards guanine. Inactive towards xanthine. Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.984 |
apt | rihB | b0469 | b2162 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Ribonucleoside hydrolase 2; Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively. Has a clear preference for cytidine over uridine. Strictly specific for ribonucleosides. Has a low but significant activity for the purine nucleoside xanthosine; Belongs to the IUNH family. RihB subfamily. | 0.906 |
deoD | adeD | b4384 | b3665 | Purine nucleoside phosphorylase 1; Cleavage of guanosine or inosine to respective bases and sugar-1-phosphate molecules. | Cryptic adenine deaminase; Protein involved in metabolic process; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. | 0.937 |