node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
dgoA | dgoD | b4477 | b4478 | 2-oxo-3-deoxygalactonate 6-phosphate aldolase; Involved in the degradation of galactose via the DeLey- Doudoroff pathway. Catalyzes the reversible, stereospecific retro-aldol cleavage of 2-keto-3-deoxy-6-phosphogalactonate (KDPGal) to pyruvate and D-glyceraldehyde-3-phosphate. In the synthetic direction, it catalyzes the addition of pyruvate to electrophilic aldehydes with re- facial selectivity. It can use a limited number of aldehyde substrates, including D-glyceraldehyde-3-phosphate (natural substrate), D- glyceraldehyde, glycolaldehyde, 2-pyridinecarboxaldehyde, D-ribose, D- erythr [...] | D-galactonate dehydratase; Catalyzes the dehydration of D-galactonate to 2-keto-3-deoxy- D-galactonate. | 0.992 |
dgoA | dgoK | b4477 | b3693 | 2-oxo-3-deoxygalactonate 6-phosphate aldolase; Involved in the degradation of galactose via the DeLey- Doudoroff pathway. Catalyzes the reversible, stereospecific retro-aldol cleavage of 2-keto-3-deoxy-6-phosphogalactonate (KDPGal) to pyruvate and D-glyceraldehyde-3-phosphate. In the synthetic direction, it catalyzes the addition of pyruvate to electrophilic aldehydes with re- facial selectivity. It can use a limited number of aldehyde substrates, including D-glyceraldehyde-3-phosphate (natural substrate), D- glyceraldehyde, glycolaldehyde, 2-pyridinecarboxaldehyde, D-ribose, D- erythr [...] | 2-oxo-3-deoxygalactonate kinase; Protein involved in carbohydrate catabolic process; Belongs to the DgoK family. | 0.999 |
dgoA | dgoR | b4477 | b4479 | 2-oxo-3-deoxygalactonate 6-phosphate aldolase; Involved in the degradation of galactose via the DeLey- Doudoroff pathway. Catalyzes the reversible, stereospecific retro-aldol cleavage of 2-keto-3-deoxy-6-phosphogalactonate (KDPGal) to pyruvate and D-glyceraldehyde-3-phosphate. In the synthetic direction, it catalyzes the addition of pyruvate to electrophilic aldehydes with re- facial selectivity. It can use a limited number of aldehyde substrates, including D-glyceraldehyde-3-phosphate (natural substrate), D- glyceraldehyde, glycolaldehyde, 2-pyridinecarboxaldehyde, D-ribose, D- erythr [...] | D-galactonate catabolism operon transcriptional repressor; Repressor for the dgoRKAT operon. Binds D-galactonate as an inducer. | 0.977 |
dgoA | dgoT | b4477 | b3691 | 2-oxo-3-deoxygalactonate 6-phosphate aldolase; Involved in the degradation of galactose via the DeLey- Doudoroff pathway. Catalyzes the reversible, stereospecific retro-aldol cleavage of 2-keto-3-deoxy-6-phosphogalactonate (KDPGal) to pyruvate and D-glyceraldehyde-3-phosphate. In the synthetic direction, it catalyzes the addition of pyruvate to electrophilic aldehydes with re- facial selectivity. It can use a limited number of aldehyde substrates, including D-glyceraldehyde-3-phosphate (natural substrate), D- glyceraldehyde, glycolaldehyde, 2-pyridinecarboxaldehyde, D-ribose, D- erythr [...] | D-galactonate transporter; Intake of galactonate into the cell; Belongs to the major facilitator superfamily. Phthalate permease family. | 0.923 |
dgoA | rspA | b4477 | b1581 | 2-oxo-3-deoxygalactonate 6-phosphate aldolase; Involved in the degradation of galactose via the DeLey- Doudoroff pathway. Catalyzes the reversible, stereospecific retro-aldol cleavage of 2-keto-3-deoxy-6-phosphogalactonate (KDPGal) to pyruvate and D-glyceraldehyde-3-phosphate. In the synthetic direction, it catalyzes the addition of pyruvate to electrophilic aldehydes with re- facial selectivity. It can use a limited number of aldehyde substrates, including D-glyceraldehyde-3-phosphate (natural substrate), D- glyceraldehyde, glycolaldehyde, 2-pyridinecarboxaldehyde, D-ribose, D- erythr [...] | Bifunctional D-altronate/D-mannonate dehydratase; Probably involved in the degradation of homoserine lactone (HSL) or of a metabolite of HSL that signals starvation. | 0.584 |
dgoA | yidX | b4477 | b3696 | 2-oxo-3-deoxygalactonate 6-phosphate aldolase; Involved in the degradation of galactose via the DeLey- Doudoroff pathway. Catalyzes the reversible, stereospecific retro-aldol cleavage of 2-keto-3-deoxy-6-phosphogalactonate (KDPGal) to pyruvate and D-glyceraldehyde-3-phosphate. In the synthetic direction, it catalyzes the addition of pyruvate to electrophilic aldehydes with re- facial selectivity. It can use a limited number of aldehyde substrates, including D-glyceraldehyde-3-phosphate (natural substrate), D- glyceraldehyde, glycolaldehyde, 2-pyridinecarboxaldehyde, D-ribose, D- erythr [...] | Putative replicase EC 2.7.-. | 0.427 |
dgoD | dgoA | b4478 | b4477 | D-galactonate dehydratase; Catalyzes the dehydration of D-galactonate to 2-keto-3-deoxy- D-galactonate. | 2-oxo-3-deoxygalactonate 6-phosphate aldolase; Involved in the degradation of galactose via the DeLey- Doudoroff pathway. Catalyzes the reversible, stereospecific retro-aldol cleavage of 2-keto-3-deoxy-6-phosphogalactonate (KDPGal) to pyruvate and D-glyceraldehyde-3-phosphate. In the synthetic direction, it catalyzes the addition of pyruvate to electrophilic aldehydes with re- facial selectivity. It can use a limited number of aldehyde substrates, including D-glyceraldehyde-3-phosphate (natural substrate), D- glyceraldehyde, glycolaldehyde, 2-pyridinecarboxaldehyde, D-ribose, D- erythr [...] | 0.992 |
dgoD | dgoK | b4478 | b3693 | D-galactonate dehydratase; Catalyzes the dehydration of D-galactonate to 2-keto-3-deoxy- D-galactonate. | 2-oxo-3-deoxygalactonate kinase; Protein involved in carbohydrate catabolic process; Belongs to the DgoK family. | 0.999 |
dgoD | dgoR | b4478 | b4479 | D-galactonate dehydratase; Catalyzes the dehydration of D-galactonate to 2-keto-3-deoxy- D-galactonate. | D-galactonate catabolism operon transcriptional repressor; Repressor for the dgoRKAT operon. Binds D-galactonate as an inducer. | 0.985 |
dgoD | dgoT | b4478 | b3691 | D-galactonate dehydratase; Catalyzes the dehydration of D-galactonate to 2-keto-3-deoxy- D-galactonate. | D-galactonate transporter; Intake of galactonate into the cell; Belongs to the major facilitator superfamily. Phthalate permease family. | 0.924 |
dgoD | yidR | b4478 | b3689 | D-galactonate dehydratase; Catalyzes the dehydration of D-galactonate to 2-keto-3-deoxy- D-galactonate. | DUF3748 family protein. | 0.729 |
dgoD | yidX | b4478 | b3696 | D-galactonate dehydratase; Catalyzes the dehydration of D-galactonate to 2-keto-3-deoxy- D-galactonate. | Putative replicase EC 2.7.-. | 0.427 |
dgoK | dgoA | b3693 | b4477 | 2-oxo-3-deoxygalactonate kinase; Protein involved in carbohydrate catabolic process; Belongs to the DgoK family. | 2-oxo-3-deoxygalactonate 6-phosphate aldolase; Involved in the degradation of galactose via the DeLey- Doudoroff pathway. Catalyzes the reversible, stereospecific retro-aldol cleavage of 2-keto-3-deoxy-6-phosphogalactonate (KDPGal) to pyruvate and D-glyceraldehyde-3-phosphate. In the synthetic direction, it catalyzes the addition of pyruvate to electrophilic aldehydes with re- facial selectivity. It can use a limited number of aldehyde substrates, including D-glyceraldehyde-3-phosphate (natural substrate), D- glyceraldehyde, glycolaldehyde, 2-pyridinecarboxaldehyde, D-ribose, D- erythr [...] | 0.999 |
dgoK | dgoD | b3693 | b4478 | 2-oxo-3-deoxygalactonate kinase; Protein involved in carbohydrate catabolic process; Belongs to the DgoK family. | D-galactonate dehydratase; Catalyzes the dehydration of D-galactonate to 2-keto-3-deoxy- D-galactonate. | 0.999 |
dgoK | dgoR | b3693 | b4479 | 2-oxo-3-deoxygalactonate kinase; Protein involved in carbohydrate catabolic process; Belongs to the DgoK family. | D-galactonate catabolism operon transcriptional repressor; Repressor for the dgoRKAT operon. Binds D-galactonate as an inducer. | 0.992 |
dgoK | dgoT | b3693 | b3691 | 2-oxo-3-deoxygalactonate kinase; Protein involved in carbohydrate catabolic process; Belongs to the DgoK family. | D-galactonate transporter; Intake of galactonate into the cell; Belongs to the major facilitator superfamily. Phthalate permease family. | 0.947 |
dgoK | idnO | b3693 | b4266 | 2-oxo-3-deoxygalactonate kinase; Protein involved in carbohydrate catabolic process; Belongs to the DgoK family. | 5-keto-D-gluconate-5-reductase; Catalyzes the reduction of 5-keto-D-gluconate to D-gluconate, using either NADH or NADPH. Is likely involved in an L-idonate degradation pathway that allows E.coli to utilize L-idonate as the sole carbon and energy source. Is also able to catalyze the reverse reaction in vitro, but the D-gluconate oxidation by the enzyme can only proceed with NAD; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.465 |
dgoK | rspA | b3693 | b1581 | 2-oxo-3-deoxygalactonate kinase; Protein involved in carbohydrate catabolic process; Belongs to the DgoK family. | Bifunctional D-altronate/D-mannonate dehydratase; Probably involved in the degradation of homoserine lactone (HSL) or of a metabolite of HSL that signals starvation. | 0.531 |
dgoK | ygbK | b3693 | b2737 | 2-oxo-3-deoxygalactonate kinase; Protein involved in carbohydrate catabolic process; Belongs to the DgoK family. | FliA-regulated DUF1537 family protein; Catalyzes the ATP-dependent phosphorylation of 3-oxo- tetronate to 3-oxo-tetronate 4-phosphate. | 0.499 |
dgoK | yidR | b3693 | b3689 | 2-oxo-3-deoxygalactonate kinase; Protein involved in carbohydrate catabolic process; Belongs to the DgoK family. | DUF3748 family protein. | 0.709 |