node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
betT | caiT | b0314 | b0040 | Choline transporter of high affinity; High-affinity uptake of choline driven by a proton-motive force; Belongs to the BCCT transporter (TC 2.A.15) family. | Putative transporter; Catalyzes the exchange of L-carnitine for gamma-butyrobetaine and related betaines. | 0.461 |
betT | proP | b0314 | b4111 | Choline transporter of high affinity; High-affinity uptake of choline driven by a proton-motive force; Belongs to the BCCT transporter (TC 2.A.15) family. | Proline/glycine betaine transporter; Proton symporter that senses osmotic shifts and responds by importing osmolytes such as proline, glycine betaine, stachydrine, pipecolic acid, ectoine and taurine. It is both an osmosensor and an osmoregulator which is available to participate early in the bacterial osmoregulatory response; Belongs to the major facilitator superfamily. Metabolite:H+ Symporter (MHS) family (TC 2.A.1.6) family. | 0.811 |
betT | proV | b0314 | b2677 | Choline transporter of high affinity; High-affinity uptake of choline driven by a proton-motive force; Belongs to the BCCT transporter (TC 2.A.15) family. | Glycine betaine/proline ABC transporter periplasmic binding protein; Part of the ProU ABC transporter complex involved in glycine betaine and proline betaine uptake. Probably responsible for energy coupling to the transport system (Probable). | 0.577 |
betT | proW | b0314 | b2678 | Choline transporter of high affinity; High-affinity uptake of choline driven by a proton-motive force; Belongs to the BCCT transporter (TC 2.A.15) family. | Glycine betaine/proline ABC transporter permease; Part of the ProU ABC transporter complex involved in glycine betaine and proline betaine uptake. Probably responsible for the translocation of the substrate across the membrane (Probable); Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. | 0.559 |
betT | proX | b0314 | b2679 | Choline transporter of high affinity; High-affinity uptake of choline driven by a proton-motive force; Belongs to the BCCT transporter (TC 2.A.15) family. | Glycine betaine/proline ABC transporter periplasmic binding protein; Part of the ProU ABC transporter complex involved in glycine betaine and proline betaine uptake. Binds glycine betaine and proline betaine with high affinity. | 0.686 |
betT | putP | b0314 | b1015 | Choline transporter of high affinity; High-affinity uptake of choline driven by a proton-motive force; Belongs to the BCCT transporter (TC 2.A.15) family. | Proline:sodium symporter; Catalyzes the sodium-dependent uptake of extracellular L- proline. This protein is also capable of using lithium as the transport cation. Also catalyzes the uptake of propionate. | 0.685 |
caiT | betT | b0040 | b0314 | Putative transporter; Catalyzes the exchange of L-carnitine for gamma-butyrobetaine and related betaines. | Choline transporter of high affinity; High-affinity uptake of choline driven by a proton-motive force; Belongs to the BCCT transporter (TC 2.A.15) family. | 0.461 |
caiT | proP | b0040 | b4111 | Putative transporter; Catalyzes the exchange of L-carnitine for gamma-butyrobetaine and related betaines. | Proline/glycine betaine transporter; Proton symporter that senses osmotic shifts and responds by importing osmolytes such as proline, glycine betaine, stachydrine, pipecolic acid, ectoine and taurine. It is both an osmosensor and an osmoregulator which is available to participate early in the bacterial osmoregulatory response; Belongs to the major facilitator superfamily. Metabolite:H+ Symporter (MHS) family (TC 2.A.1.6) family. | 0.569 |
caiT | putP | b0040 | b1015 | Putative transporter; Catalyzes the exchange of L-carnitine for gamma-butyrobetaine and related betaines. | Proline:sodium symporter; Catalyzes the sodium-dependent uptake of extracellular L- proline. This protein is also capable of using lithium as the transport cation. Also catalyzes the uptake of propionate. | 0.484 |
clsA | mscS | b1249 | b2924 | Cardiolipin synthase 1; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. | Mechanosensitive channel protein, small conductance; Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions. The channel is sensitive to voltage; as the membrane is depolarized, less tension is required to open the channel and vice versa. The channel is characterized by short bursts of activ [...] | 0.461 |
clsA | proP | b1249 | b4111 | Cardiolipin synthase 1; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. | Proline/glycine betaine transporter; Proton symporter that senses osmotic shifts and responds by importing osmolytes such as proline, glycine betaine, stachydrine, pipecolic acid, ectoine and taurine. It is both an osmosensor and an osmoregulator which is available to participate early in the bacterial osmoregulatory response; Belongs to the major facilitator superfamily. Metabolite:H+ Symporter (MHS) family (TC 2.A.1.6) family. | 0.644 |
mscS | clsA | b2924 | b1249 | Mechanosensitive channel protein, small conductance; Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions. The channel is sensitive to voltage; as the membrane is depolarized, less tension is required to open the channel and vice versa. The channel is characterized by short bursts of activ [...] | Cardiolipin synthase 1; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. | 0.461 |
mscS | proP | b2924 | b4111 | Mechanosensitive channel protein, small conductance; Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions. The channel is sensitive to voltage; as the membrane is depolarized, less tension is required to open the channel and vice versa. The channel is characterized by short bursts of activ [...] | Proline/glycine betaine transporter; Proton symporter that senses osmotic shifts and responds by importing osmolytes such as proline, glycine betaine, stachydrine, pipecolic acid, ectoine and taurine. It is both an osmosensor and an osmoregulator which is available to participate early in the bacterial osmoregulatory response; Belongs to the major facilitator superfamily. Metabolite:H+ Symporter (MHS) family (TC 2.A.1.6) family. | 0.760 |
otsA | proP | b1896 | b4111 | Trehalose-6-phosphate synthase; Catalyzes the transfer of glucose from UDP-alpha-D-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6- phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor. Essential for viability of the cells at low temperatures and at elevated osmotic strength. Belongs to the glycosyltransferase 20 family. | Proline/glycine betaine transporter; Proton symporter that senses osmotic shifts and responds by importing osmolytes such as proline, glycine betaine, stachydrine, pipecolic acid, ectoine and taurine. It is both an osmosensor and an osmoregulator which is available to participate early in the bacterial osmoregulatory response; Belongs to the major facilitator superfamily. Metabolite:H+ Symporter (MHS) family (TC 2.A.1.6) family. | 0.637 |
proP | betT | b4111 | b0314 | Proline/glycine betaine transporter; Proton symporter that senses osmotic shifts and responds by importing osmolytes such as proline, glycine betaine, stachydrine, pipecolic acid, ectoine and taurine. It is both an osmosensor and an osmoregulator which is available to participate early in the bacterial osmoregulatory response; Belongs to the major facilitator superfamily. Metabolite:H+ Symporter (MHS) family (TC 2.A.1.6) family. | Choline transporter of high affinity; High-affinity uptake of choline driven by a proton-motive force; Belongs to the BCCT transporter (TC 2.A.15) family. | 0.811 |
proP | caiT | b4111 | b0040 | Proline/glycine betaine transporter; Proton symporter that senses osmotic shifts and responds by importing osmolytes such as proline, glycine betaine, stachydrine, pipecolic acid, ectoine and taurine. It is both an osmosensor and an osmoregulator which is available to participate early in the bacterial osmoregulatory response; Belongs to the major facilitator superfamily. Metabolite:H+ Symporter (MHS) family (TC 2.A.1.6) family. | Putative transporter; Catalyzes the exchange of L-carnitine for gamma-butyrobetaine and related betaines. | 0.569 |
proP | clsA | b4111 | b1249 | Proline/glycine betaine transporter; Proton symporter that senses osmotic shifts and responds by importing osmolytes such as proline, glycine betaine, stachydrine, pipecolic acid, ectoine and taurine. It is both an osmosensor and an osmoregulator which is available to participate early in the bacterial osmoregulatory response; Belongs to the major facilitator superfamily. Metabolite:H+ Symporter (MHS) family (TC 2.A.1.6) family. | Cardiolipin synthase 1; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. | 0.644 |
proP | mscS | b4111 | b2924 | Proline/glycine betaine transporter; Proton symporter that senses osmotic shifts and responds by importing osmolytes such as proline, glycine betaine, stachydrine, pipecolic acid, ectoine and taurine. It is both an osmosensor and an osmoregulator which is available to participate early in the bacterial osmoregulatory response; Belongs to the major facilitator superfamily. Metabolite:H+ Symporter (MHS) family (TC 2.A.1.6) family. | Mechanosensitive channel protein, small conductance; Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions. The channel is sensitive to voltage; as the membrane is depolarized, less tension is required to open the channel and vice versa. The channel is characterized by short bursts of activ [...] | 0.760 |
proP | otsA | b4111 | b1896 | Proline/glycine betaine transporter; Proton symporter that senses osmotic shifts and responds by importing osmolytes such as proline, glycine betaine, stachydrine, pipecolic acid, ectoine and taurine. It is both an osmosensor and an osmoregulator which is available to participate early in the bacterial osmoregulatory response; Belongs to the major facilitator superfamily. Metabolite:H+ Symporter (MHS) family (TC 2.A.1.6) family. | Trehalose-6-phosphate synthase; Catalyzes the transfer of glucose from UDP-alpha-D-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6- phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor. Essential for viability of the cells at low temperatures and at elevated osmotic strength. Belongs to the glycosyltransferase 20 family. | 0.637 |
proP | proQ | b4111 | b1831 | Proline/glycine betaine transporter; Proton symporter that senses osmotic shifts and responds by importing osmolytes such as proline, glycine betaine, stachydrine, pipecolic acid, ectoine and taurine. It is both an osmosensor and an osmoregulator which is available to participate early in the bacterial osmoregulatory response; Belongs to the major facilitator superfamily. Metabolite:H+ Symporter (MHS) family (TC 2.A.1.6) family. | RNA chaperone, putative ProP translation regulator; RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities. May regulate ProP activity through an RNA-based, post-transcriptional mechanism. | 0.811 |