node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
aes | malZ | b0476 | b0403 | Acetyl esterase; Displays esterase activity towards short chain fatty esters (acyl chain length of up to 8 carbons). Able to hydrolyze triacetylglycerol (triacetin) and tributyrylglycerol (tributyrin), but not trioleylglycerol (triolein) or cholesterol oleate. Negatively regulates MalT activity by antagonizing maltotriose binding. Inhibits MelA galactosidase activity. | Maltodextrin glucosidase; May play a role in regulating the intracellular level of maltotriose. Cleaves glucose from the reducing end of maltotriose and longer maltodextrins with a chain length of up to 7 glucose units. | 0.496 |
aes | melA | b0476 | b4119 | Acetyl esterase; Displays esterase activity towards short chain fatty esters (acyl chain length of up to 8 carbons). Able to hydrolyze triacetylglycerol (triacetin) and tributyrylglycerol (tributyrin), but not trioleylglycerol (triolein) or cholesterol oleate. Negatively regulates MalT activity by antagonizing maltotriose binding. Inhibits MelA galactosidase activity. | Alpha-galactosidase, NAD(P)-binding; Alpha-galactosidase; Protein involved in carbohydrate catabolic process and NAD biosynthetic process; Belongs to the glycosyl hydrolase 4 family. | 0.685 |
ebgA | ebgC | b3076 | b3077 | Evolved beta-D-galactosidase, alpha subunit; The wild-type enzyme is an ineffective lactase. Two classes of point mutations dramatically improve activity of the enzyme; Belongs to the glycosyl hydrolase 2 family. | Evolved beta-D-galactosidase, beta subunit; Required for full activity of the EbgA enzyme. Exact function not known. | 0.998 |
ebgA | galM | b3076 | b0756 | Evolved beta-D-galactosidase, alpha subunit; The wild-type enzyme is an ineffective lactase. Two classes of point mutations dramatically improve activity of the enzyme; Belongs to the glycosyl hydrolase 2 family. | Aldose 1-epimerase; Mutarotase converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose. | 0.927 |
ebgA | lacZ | b3076 | b0344 | Evolved beta-D-galactosidase, alpha subunit; The wild-type enzyme is an ineffective lactase. Two classes of point mutations dramatically improve activity of the enzyme; Belongs to the glycosyl hydrolase 2 family. | beta-D-galactosidase; Protein involved in carbohydrate catabolic process; Belongs to the glycosyl hydrolase 2 family. | 0.925 |
ebgA | melA | b3076 | b4119 | Evolved beta-D-galactosidase, alpha subunit; The wild-type enzyme is an ineffective lactase. Two classes of point mutations dramatically improve activity of the enzyme; Belongs to the glycosyl hydrolase 2 family. | Alpha-galactosidase, NAD(P)-binding; Alpha-galactosidase; Protein involved in carbohydrate catabolic process and NAD biosynthetic process; Belongs to the glycosyl hydrolase 4 family. | 0.938 |
ebgA | yihR | b3076 | b3879 | Evolved beta-D-galactosidase, alpha subunit; The wild-type enzyme is an ineffective lactase. Two classes of point mutations dramatically improve activity of the enzyme; Belongs to the glycosyl hydrolase 2 family. | Putative sulphoquinovose mutarotase; Putative aldose-1-epimerase. | 0.916 |
ebgC | ebgA | b3077 | b3076 | Evolved beta-D-galactosidase, beta subunit; Required for full activity of the EbgA enzyme. Exact function not known. | Evolved beta-D-galactosidase, alpha subunit; The wild-type enzyme is an ineffective lactase. Two classes of point mutations dramatically improve activity of the enzyme; Belongs to the glycosyl hydrolase 2 family. | 0.998 |
ebgC | galM | b3077 | b0756 | Evolved beta-D-galactosidase, beta subunit; Required for full activity of the EbgA enzyme. Exact function not known. | Aldose 1-epimerase; Mutarotase converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose. | 0.900 |
ebgC | lacZ | b3077 | b0344 | Evolved beta-D-galactosidase, beta subunit; Required for full activity of the EbgA enzyme. Exact function not known. | beta-D-galactosidase; Protein involved in carbohydrate catabolic process; Belongs to the glycosyl hydrolase 2 family. | 0.904 |
ebgC | melA | b3077 | b4119 | Evolved beta-D-galactosidase, beta subunit; Required for full activity of the EbgA enzyme. Exact function not known. | Alpha-galactosidase, NAD(P)-binding; Alpha-galactosidase; Protein involved in carbohydrate catabolic process and NAD biosynthetic process; Belongs to the glycosyl hydrolase 4 family. | 0.900 |
ebgC | yihR | b3077 | b3879 | Evolved beta-D-galactosidase, beta subunit; Required for full activity of the EbgA enzyme. Exact function not known. | Putative sulphoquinovose mutarotase; Putative aldose-1-epimerase. | 0.900 |
galM | ebgA | b0756 | b3076 | Aldose 1-epimerase; Mutarotase converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose. | Evolved beta-D-galactosidase, alpha subunit; The wild-type enzyme is an ineffective lactase. Two classes of point mutations dramatically improve activity of the enzyme; Belongs to the glycosyl hydrolase 2 family. | 0.927 |
galM | ebgC | b0756 | b3077 | Aldose 1-epimerase; Mutarotase converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose. | Evolved beta-D-galactosidase, beta subunit; Required for full activity of the EbgA enzyme. Exact function not known. | 0.900 |
galM | lacZ | b0756 | b0344 | Aldose 1-epimerase; Mutarotase converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose. | beta-D-galactosidase; Protein involved in carbohydrate catabolic process; Belongs to the glycosyl hydrolase 2 family. | 0.950 |
galM | melA | b0756 | b4119 | Aldose 1-epimerase; Mutarotase converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose. | Alpha-galactosidase, NAD(P)-binding; Alpha-galactosidase; Protein involved in carbohydrate catabolic process and NAD biosynthetic process; Belongs to the glycosyl hydrolase 4 family. | 0.903 |
galM | yihR | b0756 | b3879 | Aldose 1-epimerase; Mutarotase converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose. | Putative sulphoquinovose mutarotase; Putative aldose-1-epimerase. | 0.900 |
lacZ | ebgA | b0344 | b3076 | beta-D-galactosidase; Protein involved in carbohydrate catabolic process; Belongs to the glycosyl hydrolase 2 family. | Evolved beta-D-galactosidase, alpha subunit; The wild-type enzyme is an ineffective lactase. Two classes of point mutations dramatically improve activity of the enzyme; Belongs to the glycosyl hydrolase 2 family. | 0.925 |
lacZ | ebgC | b0344 | b3077 | beta-D-galactosidase; Protein involved in carbohydrate catabolic process; Belongs to the glycosyl hydrolase 2 family. | Evolved beta-D-galactosidase, beta subunit; Required for full activity of the EbgA enzyme. Exact function not known. | 0.904 |
lacZ | galM | b0344 | b0756 | beta-D-galactosidase; Protein involved in carbohydrate catabolic process; Belongs to the glycosyl hydrolase 2 family. | Aldose 1-epimerase; Mutarotase converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose. | 0.950 |