STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yjiXDUF466 family protein; To E.coli YbdD. (67 aa)    
Predicted Functional Partners:
yjiA
Metal-binding GTPase; Binds GTP and has low GTPase activity. May have a GTP- dependent regulatory function; Belongs to the SIMIBI class G3E GTPase family. CobW subfamily.
 
  
 0.998
yjiY
Putative transporter; Transports pyruvate with a high affinity and specificity. The process is driven by the proton motive force. Part of a nutrient-sensing regulatory network composed of the two-component regulatory systems BtsS/BtsR and YpdA/YpdB, and their respective target proteins, BtsT and YhjX. Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
  
 0.997
cstA
Carbon starvation protein involved in peptide utilization; Involved in peptide utilization during carbon starvation.
    0.854
yeiR
Zn-stimulated GTPase involved in zinc homeostasis; Involved in metal homeostasis. Has GTPase activity. Binds several Zn(2+) ions in vitro.
  
  
 0.796
slyD
FKBP-type peptidyl prolyl cis-trans isomerase (rotamase); Folding helper with both chaperone and peptidyl-prolyl cis- trans isomerase (PPIase) activities. Chaperone activity prevents aggregation of unfolded or partially folded proteins and promotes their correct folding. PPIases catalyze the cis-trans isomerization of Xaa- Pro bonds of peptides, which accelerates slow steps of protein folding and thus shortens the lifetime of intermediates. Both strategies lower the concentration of intermediates and increase the productivity and yield of the folding reaction. SlyD could be involved in [...]
    
 
 0.546
yhjG
Putative inner membrane-anchored periplasmic AsmA family protein.
  
     0.539
hypB
GTP hydrolase involved in nickel liganding into hydrogenases; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. Exhibits a low intrinsic GTPase activity, which is essential for nickel insertion. In the presence of GDP, nickel, but not zinc, is transferred from the HypB GTPase domain (G-domain) to HypA. Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.
      
 0.530
yadV
Putative periplasmic pilin chaperone; Part of the yadCKLM-htrE-yadVN fimbrial operon. Could contribute to adhesion to various surfaces in specific environmental niches.
  
     0.491
htrE
Putative outer membrane usher protein; Part of the yadCKLM-htrE-yadVN fimbrial operon. Could contribute to adhesion to various surfaces in specific environmental niches. Probably involved in the export and assembly of fimbrial subunits across the outer membrane.
  
     0.472
fimD
Fimbrial usher outer membrane porin protein; Involved in the export and assembly of FimA fimbrial subunits across the outer membrane.
  
     0.435
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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