node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ais | arnT | b2252 | b2257 | Putative LPS core heptose(II)-phosphate phosphatase; Catalyzes the dephosphorylation of heptose(II) of the outer membrane lipopolysaccharide core; Belongs to the phosphoglycerate mutase family. Ais subfamily. | 4-amino-4-deoxy-L-arabinose transferase; Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides. | 0.900 |
ais | creD | b2252 | b4400 | Putative LPS core heptose(II)-phosphate phosphatase; Catalyzes the dephosphorylation of heptose(II) of the outer membrane lipopolysaccharide core; Belongs to the phosphoglycerate mutase family. Ais subfamily. | Inner membrane protein; Tolerance to colicin E2. | 0.682 |
ais | yjbM | b2252 | b4048 | Putative LPS core heptose(II)-phosphate phosphatase; Catalyzes the dephosphorylation of heptose(II) of the outer membrane lipopolysaccharide core; Belongs to the phosphoglycerate mutase family. Ais subfamily. | Uncharacterized protein. | 0.645 |
arnT | ais | b2257 | b2252 | 4-amino-4-deoxy-L-arabinose transferase; Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides. | Putative LPS core heptose(II)-phosphate phosphatase; Catalyzes the dephosphorylation of heptose(II) of the outer membrane lipopolysaccharide core; Belongs to the phosphoglycerate mutase family. Ais subfamily. | 0.900 |
arnT | cbrA | b2257 | b3690 | 4-amino-4-deoxy-L-arabinose transferase; Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides. | Colicin M resistance protein; FAD-binding protein, putative oxidoreductase; Belongs to the CbrA family. | 0.567 |
arnT | creD | b2257 | b4400 | 4-amino-4-deoxy-L-arabinose transferase; Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides. | Inner membrane protein; Tolerance to colicin E2. | 0.654 |
bglJ | creC | b4366 | b4399 | Bgl operon transcriptional activator; A crytic transcriptional activator. When its expression is induced it relieves H-NS repression of the bgl operon. Acts independently of transcription factor LeuO. | Sensory histidine kinase in two-component regulatory system with CreB or PhoB; Member of the two-component regulatory system CreC/CreB involved in catabolic regulation. CreC may function as a membrane- associated protein kinase that phosphorylates CreB in response to environmental signals. CreC can also phosphorylate PhoB. | 0.509 |
bglJ | creD | b4366 | b4400 | Bgl operon transcriptional activator; A crytic transcriptional activator. When its expression is induced it relieves H-NS repression of the bgl operon. Acts independently of transcription factor LeuO. | Inner membrane protein; Tolerance to colicin E2. | 0.639 |
cbrA | arnT | b3690 | b2257 | Colicin M resistance protein; FAD-binding protein, putative oxidoreductase; Belongs to the CbrA family. | 4-amino-4-deoxy-L-arabinose transferase; Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides. | 0.567 |
cbrA | creD | b3690 | b4400 | Colicin M resistance protein; FAD-binding protein, putative oxidoreductase; Belongs to the CbrA family. | Inner membrane protein; Tolerance to colicin E2. | 0.768 |
creA | creB | b4397 | b4398 | Putative periplasmic protein. | Response regulator in two-component regulatory system with CreC; Member of the two-component regulatory system CreC/CreB involved in catabolic regulation. | 0.973 |
creA | creC | b4397 | b4399 | Putative periplasmic protein. | Sensory histidine kinase in two-component regulatory system with CreB or PhoB; Member of the two-component regulatory system CreC/CreB involved in catabolic regulation. CreC may function as a membrane- associated protein kinase that phosphorylates CreB in response to environmental signals. CreC can also phosphorylate PhoB. | 0.992 |
creA | creD | b4397 | b4400 | Putative periplasmic protein. | Inner membrane protein; Tolerance to colicin E2. | 0.914 |
creB | creA | b4398 | b4397 | Response regulator in two-component regulatory system with CreC; Member of the two-component regulatory system CreC/CreB involved in catabolic regulation. | Putative periplasmic protein. | 0.973 |
creB | creC | b4398 | b4399 | Response regulator in two-component regulatory system with CreC; Member of the two-component regulatory system CreC/CreB involved in catabolic regulation. | Sensory histidine kinase in two-component regulatory system with CreB or PhoB; Member of the two-component regulatory system CreC/CreB involved in catabolic regulation. CreC may function as a membrane- associated protein kinase that phosphorylates CreB in response to environmental signals. CreC can also phosphorylate PhoB. | 0.999 |
creB | creD | b4398 | b4400 | Response regulator in two-component regulatory system with CreC; Member of the two-component regulatory system CreC/CreB involved in catabolic regulation. | Inner membrane protein; Tolerance to colicin E2. | 0.936 |
creC | bglJ | b4399 | b4366 | Sensory histidine kinase in two-component regulatory system with CreB or PhoB; Member of the two-component regulatory system CreC/CreB involved in catabolic regulation. CreC may function as a membrane- associated protein kinase that phosphorylates CreB in response to environmental signals. CreC can also phosphorylate PhoB. | Bgl operon transcriptional activator; A crytic transcriptional activator. When its expression is induced it relieves H-NS repression of the bgl operon. Acts independently of transcription factor LeuO. | 0.509 |
creC | creA | b4399 | b4397 | Sensory histidine kinase in two-component regulatory system with CreB or PhoB; Member of the two-component regulatory system CreC/CreB involved in catabolic regulation. CreC may function as a membrane- associated protein kinase that phosphorylates CreB in response to environmental signals. CreC can also phosphorylate PhoB. | Putative periplasmic protein. | 0.992 |
creC | creB | b4399 | b4398 | Sensory histidine kinase in two-component regulatory system with CreB or PhoB; Member of the two-component regulatory system CreC/CreB involved in catabolic regulation. CreC may function as a membrane- associated protein kinase that phosphorylates CreB in response to environmental signals. CreC can also phosphorylate PhoB. | Response regulator in two-component regulatory system with CreC; Member of the two-component regulatory system CreC/CreB involved in catabolic regulation. | 0.999 |
creC | creD | b4399 | b4400 | Sensory histidine kinase in two-component regulatory system with CreB or PhoB; Member of the two-component regulatory system CreC/CreB involved in catabolic regulation. CreC may function as a membrane- associated protein kinase that phosphorylates CreB in response to environmental signals. CreC can also phosphorylate PhoB. | Inner membrane protein; Tolerance to colicin E2. | 0.990 |