node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
blr | cnu | b4409 | b1625 | Beta-lactam resistance membrane protein; Component of the cell division machinery, which is probably involved in the stabilization of the divisome under certain stress conditions. | Nucleoid-associated oriC-binding protein; Modifies the set of genes regulated by H-NS; Hha and Cnu (YdgT) increase the number of genes bound by H-NS/StpA and may also modulate the oligomerization of the H-NS/StpA-complex on DNA. The complex formed with H-NS binds to the specific 26-bp cnb site in the origin of replication oriC. Can complement, at least partially, the absence of the Hha protein in hha mutants. | 0.602 |
blr | creD | b4409 | b4400 | Beta-lactam resistance membrane protein; Component of the cell division machinery, which is probably involved in the stabilization of the divisome under certain stress conditions. | Inner membrane protein; Tolerance to colicin E2. | 0.529 |
blr | ftsI | b4409 | b0084 | Beta-lactam resistance membrane protein; Component of the cell division machinery, which is probably involved in the stabilization of the divisome under certain stress conditions. | Transpeptidase involved in septal peptidoglycan synthesis; Essential cell division protein that catalyzes cross-linking of the peptidoglycan cell wall at the division septum. Required for localization of FtsN. Belongs to the transpeptidase family. FtsI subfamily. | 0.536 |
blr | ftsL | b4409 | b0083 | Beta-lactam resistance membrane protein; Component of the cell division machinery, which is probably involved in the stabilization of the divisome under certain stress conditions. | Membrane bound cell division leucine zipper septum protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. Can also mediate Zn(2+)-sensitivity probably by increasing the permeability of the inner membrane. Belongs to the FtsL family. | 0.538 |
blr | kdpF | b4409 | b4513 | Beta-lactam resistance membrane protein; Component of the cell division machinery, which is probably involved in the stabilization of the divisome under certain stress conditions. | Potassium ion accessory transporter subunit; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit may be involved in stabilization of the complex. | 0.627 |
blr | lplA | b4409 | b4386 | Beta-lactam resistance membrane protein; Component of the cell division machinery, which is probably involved in the stabilization of the divisome under certain stress conditions. | Lipoate-protein ligase A; Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes. Is also able to catalyze very poorly the transfer of lipoyl and octanoyl moiety from their acyl carrier protein. | 0.686 |
blr | sgrT | b4409 | b4662 | Beta-lactam resistance membrane protein; Component of the cell division machinery, which is probably involved in the stabilization of the divisome under certain stress conditions. | Inhibitor of glucose uptake; Acts to promote recovery from glucose-phosphate stress due to intracellular accumulation of glucose-6-phosphate caused by disruption of glycolytic flux or in the presence of (toxic) non-metabolizable glucose phosphate analogs. It may do so by inhibiting the transporter activity for glucose uptake (PtsG) as cells that overexpress this protein do not seem to import glucose although they have nearly wild- type levels of PtsG. | 0.543 |
blr | ydgJ | b4409 | b1624 | Beta-lactam resistance membrane protein; Component of the cell division machinery, which is probably involved in the stabilization of the divisome under certain stress conditions. | Putative oxidoreductase. | 0.700 |
blr | ymgF | b4409 | b4520 | Beta-lactam resistance membrane protein; Component of the cell division machinery, which is probably involved in the stabilization of the divisome under certain stress conditions. | Inner membrane division septum protein; Could be involved in cell division. May participate in the stabilization of the cell divisome under specific conditions. | 0.858 |
blr | yqcG | b4409 | b4682 | Beta-lactam resistance membrane protein; Component of the cell division machinery, which is probably involved in the stabilization of the divisome under certain stress conditions. | Membrane stress resistance protein. | 0.529 |
cnu | blr | b1625 | b4409 | Nucleoid-associated oriC-binding protein; Modifies the set of genes regulated by H-NS; Hha and Cnu (YdgT) increase the number of genes bound by H-NS/StpA and may also modulate the oligomerization of the H-NS/StpA-complex on DNA. The complex formed with H-NS binds to the specific 26-bp cnb site in the origin of replication oriC. Can complement, at least partially, the absence of the Hha protein in hha mutants. | Beta-lactam resistance membrane protein; Component of the cell division machinery, which is probably involved in the stabilization of the divisome under certain stress conditions. | 0.602 |
cnu | ydgJ | b1625 | b1624 | Nucleoid-associated oriC-binding protein; Modifies the set of genes regulated by H-NS; Hha and Cnu (YdgT) increase the number of genes bound by H-NS/StpA and may also modulate the oligomerization of the H-NS/StpA-complex on DNA. The complex formed with H-NS binds to the specific 26-bp cnb site in the origin of replication oriC. Can complement, at least partially, the absence of the Hha protein in hha mutants. | Putative oxidoreductase. | 0.487 |
creD | blr | b4400 | b4409 | Inner membrane protein; Tolerance to colicin E2. | Beta-lactam resistance membrane protein; Component of the cell division machinery, which is probably involved in the stabilization of the divisome under certain stress conditions. | 0.529 |
ftsI | blr | b0084 | b4409 | Transpeptidase involved in septal peptidoglycan synthesis; Essential cell division protein that catalyzes cross-linking of the peptidoglycan cell wall at the division septum. Required for localization of FtsN. Belongs to the transpeptidase family. FtsI subfamily. | Beta-lactam resistance membrane protein; Component of the cell division machinery, which is probably involved in the stabilization of the divisome under certain stress conditions. | 0.536 |
ftsI | ftsL | b0084 | b0083 | Transpeptidase involved in septal peptidoglycan synthesis; Essential cell division protein that catalyzes cross-linking of the peptidoglycan cell wall at the division septum. Required for localization of FtsN. Belongs to the transpeptidase family. FtsI subfamily. | Membrane bound cell division leucine zipper septum protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. Can also mediate Zn(2+)-sensitivity probably by increasing the permeability of the inner membrane. Belongs to the FtsL family. | 0.999 |
ftsI | ymgF | b0084 | b4520 | Transpeptidase involved in septal peptidoglycan synthesis; Essential cell division protein that catalyzes cross-linking of the peptidoglycan cell wall at the division septum. Required for localization of FtsN. Belongs to the transpeptidase family. FtsI subfamily. | Inner membrane division septum protein; Could be involved in cell division. May participate in the stabilization of the cell divisome under specific conditions. | 0.836 |
ftsL | blr | b0083 | b4409 | Membrane bound cell division leucine zipper septum protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. Can also mediate Zn(2+)-sensitivity probably by increasing the permeability of the inner membrane. Belongs to the FtsL family. | Beta-lactam resistance membrane protein; Component of the cell division machinery, which is probably involved in the stabilization of the divisome under certain stress conditions. | 0.538 |
ftsL | ftsI | b0083 | b0084 | Membrane bound cell division leucine zipper septum protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. Can also mediate Zn(2+)-sensitivity probably by increasing the permeability of the inner membrane. Belongs to the FtsL family. | Transpeptidase involved in septal peptidoglycan synthesis; Essential cell division protein that catalyzes cross-linking of the peptidoglycan cell wall at the division septum. Required for localization of FtsN. Belongs to the transpeptidase family. FtsI subfamily. | 0.999 |
ftsL | ymgF | b0083 | b4520 | Membrane bound cell division leucine zipper septum protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. Can also mediate Zn(2+)-sensitivity probably by increasing the permeability of the inner membrane. Belongs to the FtsL family. | Inner membrane division septum protein; Could be involved in cell division. May participate in the stabilization of the cell divisome under specific conditions. | 0.869 |
kdpF | blr | b4513 | b4409 | Potassium ion accessory transporter subunit; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit may be involved in stabilization of the complex. | Beta-lactam resistance membrane protein; Component of the cell division machinery, which is probably involved in the stabilization of the divisome under certain stress conditions. | 0.627 |