searching ... STRING: functional protein association networks

Version:
12.0

The following proteins in Mus musculus appear to match your input.
Please review the list, then click 'Continue' to proceed.

<- Back ⤓ Mapping Continue ->

101 query items

showing page 1 of 6 • first • previous • next • last

1) '10090.ENSMUSP00000032125':

Bmp10 - Bone morphogenetic protein 10; Required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Inhibits endothelial cell migration and growth. May reduce cell migration and cell matrix adhesion in breast cancer cell lines (By similarity). Belongs to the TGF-be [...] [a.k.a. NP_033886, NP_033886.2, ENSMUSP00000032125]

2) '10090.ENSMUSP00000079689':

Dab2 - Disabled homolog 2; Adapter protein that functions as clathrin-associated sorting protein (CLASP) required for clathrin-mediated endocytosis of selected cargo proteins. Can bind and assemble clathrin, and binds simultaneously to phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) and cargos containing non-phosphorylated NPXY internalization motifs, such as the LDL receptor, to recruit them to clathrin-coated pits. Can function in clathrin-mediated endocytosis independently of the AP-2 complex. Involved in endocytosis of integrin beta-1; this function seems to redundant with the AP-2 [...] [a.k.a. UPI0001889C68, ENSMUST00000110664, BAB22405.1]

3) '10090.ENSMUSP00000076682':

Chst15 - Carbohydrate sulfotransferase 15; Sulfotransferase that transfers sulfate from 3'- phosphoadenosine 5'-phosphosulfate (PAPS) to the C-6 hydroxyl group of the GalNAc 4-sulfate residue of chondroitin sulfate A and forms chondroitin sulfate E containing GlcA-GalNAc(4,6-SO(4)) repeating units. It also transfers sulfate to a unique non-reducing terminal sequence, GalNAc(4SO4)-GlcA(2SO4)-GalNAc(6SO4), to yield a highly sulfated structure similar to the structure found in thrombomodulin chondroitin sulfate. May also act as a B-cell receptor involved in BCR ligation-mediated early activation t [...] [a.k.a. Q91XQ5, ENSMUSG00000030930, BAC38968.1]

4) '10090.ENSMUSP00000030897':

Megf6 - Multiple epidermal growth factor-like domains protein 6. [a.k.a. XM_006538826.2, UPI000059E26A, 2600001P17Rik]

5) '10090.ENSMUSP00000066235':

Smco3 - Single-pass membrane and coiled-coil domain-containing protein 3. [a.k.a. ENSMUSP00000066235, BAC32422.1, 654818]

6) '10090.ENSMUSP00000060099':

Tacstd2 - Tumor-associated calcium signal transducer 2; May function as a growth factor receptor. [a.k.a. ENSMUST00000058178.5, BAC39531.1, EGP-1]

7) '10090.ENSMUSP00000047623':

Wtip - Wilms tumor protein 1-interacting protein; Adapter or scaffold protein which participates in the assembly of numerous protein complexes and is involved in several cellular processes such as cell fate determination, cytoskeletal organization, repression of gene transcription, cell-cell adhesion, cell differentiation, proliferation and migration. Positively regulates microRNA (miRNA)-mediated gene silencing. Negatively regulates Hippo signaling pathway and antagonizes phosphorylation of YAP1. Acts as a transcriptional corepressor for SNAI1 and SNAI2/SLUG-dependent repression of E-cadheri [...] [a.k.a. NM_207212.2, ENSMUST00000140911, CCDS21135.1]

8) '10090.ENSMUSP00000103658':

Ccne1 - G1/S-specific cyclin-E1; Essential for the control of the cell cycle at the G1/S (start) transition. [a.k.a. R-MMU-453279, AC166334, R-MMU-69306]

9) '10090.ENSMUSP00000064934':

Cd177 - CD177 antigen; In association with beta-2 integrin heterodimer ITGAM/CD11b and ITGB2/CD18, mediates activation of TNF-alpha primed neutrophils including degranulation and superoxide production (By similarity). In addition, by preventing beta-2 integrin internalization and attenuating chemokine signaling favors adhesion over migration (By similarity). Heterophilic interaction with PECAM1 on endothelial cells plays a role in neutrophil transendothelial migration in vitro (By similarity). However, appears to be dispensable for neutrophil recruitment caused by bacterial infection in vivo. [...] [a.k.a. ENSMUST00000063956, XP_011248990.1, BC027283]

10) '10090.ENSMUSP00000043966':

Arsi - Arylsulfatase I; Displays arylsulfatase activity at neutral pH, when co- expressed with SUMF1; arylsulfatase activity is measured in the secretion medium of retinal cell line, but no activity is recorded when measured in cell extracts; Belongs to the sulfatase family. [a.k.a. R-MMU-163841, BC141169, R-MMU-392499]

11) '10090.ENSMUSP00000003628':