searching ... STRING: functional protein association networks

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The following proteins in Mus musculus appear to match your input.
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101 query items

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1) '10090.ENSMUSP00000033721':

Arhgap6 - Rho GTPase-activating protein 6; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Could regulate the interactions of signaling molecules with the actin cytoskeleton. Promotes continuous elongation of cytoplasmic processes during cell motility and simultaneous retraction of the cell body changing the cell morphology (By similarity). [a.k.a. NR_109847, ENSMUSP00000134512, NM_178754.3]

2) '10090.ENSMUSP00000044069':

Zfc3h1 - Zinc finger, C3H1-type-containing. [a.k.a. ENSMUSG00000034163, Zfc3h1-203, MGI:2446143]

3) '10090.ENSMUSP00000039950':

Pmepa1 - Protein TMEPAI; Functions as a negative regulator of TGF-beta signaling and thereby probably plays a role in cell proliferation, differentiation, apoptosis, motility, extracellular matrix production and immunosuppression. In the canonical TGF-beta pathway, ZFYVE9/SARA recruits the intracellular signal transducer and transcriptional modulators SMAD2 and SMAD3 to the TGF-beta receptor. Phosphorylated by the receptor, SMAD2 and SMAD3 then form a heteromeric complex with SMAD4 that translocates to the nucleus to regulate transcription. Through interaction with SMAD2 and SMAD3, LDLRAD4 may [...] [a.k.a. 65112, Q9EQH9, NP_075371.2]

4) '10090.ENSMUSP00000123588':

Brwd3 - Bromodomain and WD repeat-containing protein 3; Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape (By similarity). [a.k.a. Brodl, NP_001074946, ENSMUSP00000098842]

5) '10090.ENSMUSP00000033139':

Ate1 - Arginyl-tRNA--protein transferase 1; Involved in the post-translational conjugation of arginine to the N-terminal aspartate or glutamate of a protein. This arginylation is required for degradation of the protein via the ubiquitin pathway. Does not arginylate cysteine residues; Belongs to the R-transferase family. [a.k.a. Q80YP1, CCDS21901.1, Ate1-201]

6) '10090.ENSMUSP00000031221':

- - Sorry, STRING found no proteins by this name in Mus musculus - -

7) '10090.ENSMUSP00000052758':

Itsn2 - Intersectin-2; Adapter protein that may provide indirect link between the endocytic membrane traffic and the actin assembly machinery. May regulate the formation of clathrin-coated vesicles (CCPs). Seems to be involved in CCPs maturation including invagination or budding. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR). Plays a role in dendrite formation by melanocytes. [a.k.a. Itsn2-205, ENSMUST00000164218, Q8C9C3]

8) '10090.ENSMUSP00000130967':

Prepl - Prolyl endopeptidase-like; Serine peptidase whose precise substrate specificity remains unclear. Does not cleave peptides after a arginine or lysine residue (By similarity). Regulates trans-Golgi network morphology and sorting by regulating the membrane binding of the AP-1 complex. May play a role in the regulation of synaptic vesicle exocytosis (By similarity). [a.k.a. AK028877, UPI00000EA20D, mmu:213760]

9) '10090.ENSMUSP00000081579':

- - Sorry, STRING found no proteins by this name in Mus musculus - -

10) '10090.ENSMUSP00000030243':

Prkaa2 - 5'-AMP-activated protein kinase catalytic subunit alpha-2; Catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts a [...] [a.k.a. 108079, XM_006502651, R-MMU-163680]

11) '10090.ENSMUSP00000047812':

- - Sorry, STRING found no proteins by this name in Mus musculus - -

12) '10090.ENSMUSP00000030460':

Gpbp1l1 - Vasculin-like protein 1; Possible transcription factor; Belongs to the vasculin family. [a.k.a. Q6NZP2, AAH31428.1, Q8K2H8]

13) '10090.ENSMUSP00000109087':

- - Sorry, STRING found no proteins by this name in Mus musculus - -

14) '10090.ENSMUSP00000070662':

- - Sorry, STRING found no proteins by this name in Mus musculus - -

15) '10090.ENSMUSP00000000349':

Dbt - 2-oxoisovalerate dehydrogenase E2 component (dihydrolipoyl transacylase); The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). Within this complex, the catalytic function of this enzyme is to accept, and to transfer to coenzyme A, acyl groups that are generated by the branched-chain alpha-keto acid decarboxylase component. [a.k.a. EC 2.3.1.168, UPI000620AA47, R-MMU-70895]

16) '10090.ENSMUSP00000137430':

Usp34 - Ubiquitin carboxyl-terminal hydrolase 34; Ubiquitin hydrolase that can remove conjugated ubiquitin from AXIN1 and AXIN2, thereby acting as a regulator of Wnt signaling pathway. Acts as an activator of the Wnt signaling pathway downstream of the beta-catenin destruction complex by deubiquitinating and stabilizing AXIN1 and AXIN2, leading to promote nuclear accumulation of AXIN1 and AXIN2 and positively regulate beta-catenin (CTNBB1)-mediated transcription. Recognizes and hydrolyzes the peptide bond at the C- terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precurs [...] [a.k.a. Ubiquitin-specific-processing protease 34, Ubiquitin carboxyl-terminal hydrolase 34, R-MMU-201681]

17) '10090.ENSMUSP00000025930':

Smc3 - Structural maintenance of chromosomes protein 3; Central component of cohesin, a complex required for chromosome cohesion during the cell cycle. The cohesin complex may form a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. Cohesion is coupled to DNA replication and is involved in DNA repair. The cohesin complex plays also an important role in spindle pole assembly during mitosis and in chromosomes movement; Belongs to the SMC family. SMC3 subfamily. [a.k.a. R-MMU-68884, R-MMU-2470946, AAD42073.1]

18) '10090.ENSMUSP00000047445':

Atad2b - ATPase family, AAA domain-containing 2B. [a.k.a. ENSMUST00000218303.1, BC032887, XM_017315116]

19) '10090.ENSMUSP00000130795':

- - Sorry, STRING found no proteins by this name in Mus musculus - -

20) '10090.ENSMUSP00000027495':

Sept2 - Septin-2; Filament-forming cytoskeletal GTPase. Forms a filamentous structure with SEPTIN12, SEPTIN6, SEPTIN2 and probably SEPTIN4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation (By similarity). Required for normal organization of the actin cytoskeleton. Plays a role in the biogenesis of polarized columnar- shaped epithelium by maintaining polyglutamylated microtubules, thus facilitating efficient vesicle transport, and by impeding MAP4 binding to tubulin. Required for the progression through mitosis [...] [a.k.a. ENSMUST00000157021.1, ENSMUST00000142401.7, AK171331]

101 query items

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