searching ... STRING: functional protein association networks

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The following proteins in Mus musculus appear to match your input.
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101 query items

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1) '10090.ENSMUSP00000128828':

Cdkn1c - Cyclin-dependent kinase inhibitor 1C; Potent tight-binding inhibitor of several G1 cyclin/CDK complexes (cyclin E-CDK2, cyclin D2-CDK4, and cyclin A-CDK2) and, to lesser extent, of the mitotic cyclin B-CDC2. Negative regulator of cell proliferation. May play a role in maintenance of the non-proliferative state throughout life. [a.k.a. R-MMU-453279, XP_006508534, BC005412]

2) '10090.ENSMUSP00000047402':

Apobec2 - C->U-editing enzyme APOBEC-2; Probable C to U editing enzyme whose physiological substrate is not yet known. Does not display detectable apoB mRNA editing. Has a low intrinsic cytidine deaminase activity. May play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation. [a.k.a. Q9WV35, ABEC2_MOUSE, AAH27530.1]

3) '10090.ENSMUSP00000113571':

Ank1 - Ankyrin-1; Attaches integral membrane proteins to cytoskeletal elements; binds to the erythrocyte membrane protein band 4.2, to Na-K ATPase, to the lymphocyte membrane protein GP85, and to the cytoskeletal proteins fodrin, tubulin, vimentin and desmin. Erythrocyte ankyrins also link spectrin (beta chain) to the cytoplasmic domain of the erythrocytes anion exchange protein; they retain most or all of these binding functions. In skeletal muscle, isoform Mu7 together with obscurin may provide a molecular link between the sarcoplasmic reticulum and myofibrils. [a.k.a. 11733, ENSMUST00000152511, AC115361]

4) '10090.ENSMUSP00000064988':

- - Sorry, STRING found no proteins by this name in Mus musculus - -

5) '10090.ENSMUSP00000080594':

- - Sorry, STRING found no proteins by this name in Mus musculus - -

6) '10090.ENSMUSP00000054462':

Pqlc3 - Solute carrier family 66 member 3. [a.k.a. PQ loop repeat containing, ENSMUSP00000152138, mmu:217430]

7) '10090.ENSMUSP00000133377':

Mpig6b - Megakaryocyte and platelet inhibitory receptor G6b; Inhibitory receptor that acts as a critical regulator of hematopoietic lineage differentiation, megakaryocyte function and platelet production. Inhibits platelet aggregation and activation by agonists such as ADP and collagen-related peptide (By similarity). This regulation of megakaryocate function as well as platelet production ann activation is done through the inhibition (via the 2 ITIM motifs) of the receptors CLEC1B and GP6:FcRgamma signaling. Appears to operate in a calcium-independent manner (By similarity). [a.k.a. D3YVS6, XP_006523482, AU023871]

8) '10090.ENSMUSP00000103658':

Ccne1 - G1/S-specific cyclin-E1; Essential for the control of the cell cycle at the G1/S (start) transition. [a.k.a. R-MMU-453279, AC166334, R-MMU-69306]

9) '10090.ENSMUSP00000106489':

Adap1 - ArfGAP with dual PH domains 1. [a.k.a. Adap1-202, 231821, ENSMUST00000156815]

10) '10090.ENSMUSP00000064934':

Cd177 - CD177 antigen; In association with beta-2 integrin heterodimer ITGAM/CD11b and ITGB2/CD18, mediates activation of TNF-alpha primed neutrophils including degranulation and superoxide production (By similarity). In addition, by preventing beta-2 integrin internalization and attenuating chemokine signaling favors adhesion over migration (By similarity). Heterophilic interaction with PECAM1 on endothelial cells plays a role in neutrophil transendothelial migration in vitro (By similarity). However, appears to be dispensable for neutrophil recruitment caused by bacterial infection in vivo. [...] [a.k.a. ENSMUST00000063956, XP_011248990.1, BC027283]

11) '10090.ENSMUSP00000058217':

- - Sorry, STRING found no proteins by this name in Mus musculus - -

12) '10090.ENSMUSP00000128278':

Iqgap1 - Ras GTPase-activating-like protein IQGAP1; Plays a crucial role in regulating the dynamics and assembly of the actin cytoskeleton. Binds to activated CDC42 but does not stimulate its GTPase activity. It associates with calmodulin. Could serve as an assembly scaffold for the organization of a multimolecular complex that would interface incoming signals to the reorganization of the actin cytoskeleton at the plasma membrane. May promote neurite outgrowth. May play a possible role in cell cycle regulation by contributing to cell cycle progression after DNA replication arrest. [a.k.a. XR_001785567.1, ENSMUST00000205813, Q9JKF1]

13) '10090.ENSMUSP00000018651':

Trpv2 - Transient receptor potential cation channel subfamily V member 2; Calcium-permeable, non-selective cation channel with an outward rectification. Seems to be regulated, at least in part, by IGF- I, PDGF and neuropeptide head activator. May transduce physical stimuli in mast cells. Activated by temperatures higher than 52 degrees Celsius; is not activated by vanilloids and acidic pH. Belongs to the transient receptor (TC 1.A.4) family. TrpV subfamily. TRPV2 sub-subfamily. [a.k.a. R-MMU-983712, UPI00000E88C6, Q9WTR1]

14) '10090.ENSMUSP00000028386':

- - Sorry, STRING found no proteins by this name in Mus musculus - -

15) '10090.ENSMUSP00000105815':

Smox - Spermine oxidase; Flavoenzyme which catalyzes the oxidation of spermine to spermidine. Can also use N(1)-acetylspermine and spermidine as substrates, with different affinity depending on the isoform (isozyme) and on the experimental conditions. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs. May contribute to beta-alanine production via aldehyde dehydrogenase conversion of 3-amino-propanal; Belongs to the flavin monoamine oxidase family. [a.k.a. Spermine oxidase, Smox-204, XP_030106358.1]

16) '10090.ENSMUSP00000020964':

Fkbp1b - Peptidyl-prolyl cis-trans isomerase FKBP1B; Has the potential to contribute to the immunosuppressive and toxic effects of FK506 and rapamycin. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity); Belongs to the FKBP-type PPIase family. FKBP1 subfamily. [a.k.a. EDL01354.1, R-MMU-983712, R-MMU-5578775]

17) '10090.ENSMUSP00000096411':

- - Sorry, STRING found no proteins by this name in Mus musculus - -

18) '10090.ENSMUSP00000098429':

Ccdc92b - Coiled-coil domain-containing 92B. [a.k.a. Coiled-coil domain containing 92B, ENSMUSG00000069814, NP_001013806]

19) '10090.ENSMUSP00000026302':

Maged2 - Melanoma antigen, family D, 2. [a.k.a. ENSMUSG00000025268, NP_109625.1, ENSMUSP00000120903]

20) '10090.ENSMUSP00000104132':

Hif3a - Hypoxia-inducible factor 3-alpha; Acts as a transcriptional regulator in adaptive response to low oxygen tension. Acts as a regulator of hypoxia-inducible gene expression. Plays a role in the development of the cardiorespiratory system. [Isoform 2]: Attenuates the ability of transcription factor HIF1A, EPAS1 and the HIF1A-ARNT complex to bind to hypoxia-responsive elements (HRE) located within the enhancer/promoter of hypoxia- inducible target genes and hence inhibits HRE-driven transcriptional activation. Functions as an inhibitor of angiogenesis in hypoxic cells of the cornea. May ac [...] [a.k.a. ENSMUSP00000104132, E9QLB1, Q8VHR1]

101 query items

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