searching ... STRING: functional protein association networks

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The following proteins in Mus musculus appear to match your input.
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101 query items

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1) '10090.ENSMUSP00000128828':

Cdkn1c - Cyclin-dependent kinase inhibitor 1C; Potent tight-binding inhibitor of several G1 cyclin/CDK complexes (cyclin E-CDK2, cyclin D2-CDK4, and cyclin A-CDK2) and, to lesser extent, of the mitotic cyclin B-CDC2. Negative regulator of cell proliferation. May play a role in maintenance of the non-proliferative state throughout life. [a.k.a. R-MMU-453279, XP_006508534, BC005412]

2) '10090.ENSMUSP00000099384':

Tnnc2 - Troponin C, skeletal muscle; Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments. [a.k.a. ENSMUST00000103095.4, R-MMU-397014, R-MMU-390522]

3) '10090.ENSMUSP00000113571':

Ank1 - Ankyrin-1; Attaches integral membrane proteins to cytoskeletal elements; binds to the erythrocyte membrane protein band 4.2, to Na-K ATPase, to the lymphocyte membrane protein GP85, and to the cytoskeletal proteins fodrin, tubulin, vimentin and desmin. Erythrocyte ankyrins also link spectrin (beta chain) to the cytoplasmic domain of the erythrocytes anion exchange protein; they retain most or all of these binding functions. In skeletal muscle, isoform Mu7 together with obscurin may provide a molecular link between the sarcoplasmic reticulum and myofibrils. [a.k.a. 11733, ENSMUST00000152511, AC115361]

4) '10090.ENSMUSP00000080694':

Rps6ka6 - Ribosomal protein S6 kinase alpha-6; Constitutively active serine/threonine-protein kinase that exhibits growth-factor-independent kinase activity and that may participate in p53/TP53-dependent cell growth arrest signaling and play an inhibitory role during embryogenesis. [a.k.a. R-MMU-442755, Rps6ka6-202, XP_006528464]

5) '10090.ENSMUSP00000017458':

Mpp2 - MAGUK p55 subfamily member 2; Postsynaptic MAGUK scaffold protein that links CADM1 cell adhesion molecules to core components of the postsynaptic density (By similarity). In CA1 pyramidal neurons, required for synaptic KCNN2- containing channel function and long-term potentiation expression. Seems to negatively regulate SRC function in epithelial cells (By similarity). [a.k.a. XP_006533746.1, AK141422, BAE24680.1]

6) '10090.ENSMUSP00000059050':

- - Sorry, STRING found no proteins by this name in Mus musculus - -

7) '10090.ENSMUSP00000064988':

- - Sorry, STRING found no proteins by this name in Mus musculus - -

8) '10090.ENSMUSP00000131860':

Gm17606 - Predicted gene, 17606. [a.k.a. ENSMUSG00000091306, F6ZL36, ENSMUSP00000131860]

9) '10090.ENSMUSP00000133377':

Mpig6b - Megakaryocyte and platelet inhibitory receptor G6b; Inhibitory receptor that acts as a critical regulator of hematopoietic lineage differentiation, megakaryocyte function and platelet production. Inhibits platelet aggregation and activation by agonists such as ADP and collagen-related peptide (By similarity). This regulation of megakaryocate function as well as platelet production ann activation is done through the inhibition (via the 2 ITIM motifs) of the receptors CLEC1B and GP6:FcRgamma signaling. Appears to operate in a calcium-independent manner (By similarity). [a.k.a. D3YVS6, XP_006523482, AU023871]

10) '10090.ENSMUSP00000044903':

Thbs1 - Thrombospondin-1; Adhesive glycoprotein that mediates cell-to-cell and cell-to- matrix interactions. Binds heparin. May play a role in dentinogenesis and/or maintenance of dentin and dental pulp. Ligand for CD36 mediating antiangiogenic properties (By similarity). Plays a role in ER stress response, via its interaction with the activating transcription factor 6 alpha (ATF6) which produces adaptive ER stress response factors. [a.k.a. R-MMU-186797, Thrombospondin-1, ENSMUSP00000044903]

11) '10090.ENSMUSP00000103658':

Ccne1 - G1/S-specific cyclin-E1; Essential for the control of the cell cycle at the G1/S (start) transition. [a.k.a. R-MMU-453279, AC166334, R-MMU-69306]

12) '10090.ENSMUSP00000064934':

Cd177 - CD177 antigen; In association with beta-2 integrin heterodimer ITGAM/CD11b and ITGB2/CD18, mediates activation of TNF-alpha primed neutrophils including degranulation and superoxide production (By similarity). In addition, by preventing beta-2 integrin internalization and attenuating chemokine signaling favors adhesion over migration (By similarity). Heterophilic interaction with PECAM1 on endothelial cells plays a role in neutrophil transendothelial migration in vitro (By similarity). However, appears to be dispensable for neutrophil recruitment caused by bacterial infection in vivo. [...] [a.k.a. ENSMUST00000063956, XP_011248990.1, BC027283]

13) '10090.ENSMUSP00000029014':

- - Sorry, STRING found no proteins by this name in Mus musculus - -

14) '10090.ENSMUSP00000083497':

- - Sorry, STRING found no proteins by this name in Mus musculus - -

15) '10090.ENSMUSP00000028386':

- - Sorry, STRING found no proteins by this name in Mus musculus - -

16) '10090.ENSMUSP00000064237':

Apol8 - Apolipoprotein L 8. [a.k.a. NP_001075439.1, XM_006520941, uc007woa.2]

17) '10090.ENSMUSP00000101938':

6030468B19Rik - Protein IL-40; Probable B cell-associated cytokine that plays a role in the regulation of humoral immune responses. Involved in lymphocyte B cell development and immunoglobulin/IgA production. [a.k.a. 77727, RIKEN cDNA 6030468B19 gene, B1ATC1]

18) '10090.ENSMUSP00000089793':

Col11a1 - Collagen alpha-1(XI) chain; May play an important role in fibrillogenesis by controlling lateral growth of collagen II fibrils; Belongs to the fibrillar collagen family. [a.k.a. ENSMUST00000196345.1, NP_031755, mmu:12814]

19) '10090.ENSMUSP00000103402':

Tmod1 - Tropomodulin-1; Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton (By similarity); Belongs to the tropomodulin family. [a.k.a. ENSMUST00000156200.7, R-MMU-397014, ENSMUST00000128689.7]

20) '10090.ENSMUSP00000002284':

Plaur - Urokinase plasminogen activator surface receptor; Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. [a.k.a. ENSMUSG00000046223, XP_006539702, U12235]

101 query items

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