searching ... STRING: functional protein association networks

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The following proteins in Homo sapiens appear to match your input.
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101 query items

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1) '9606.ENSP00000266031':

HYAL1 - Hyaluronidase-1; May have a role in promoting tumor progression. May block the TGFB1-enhanced cell growth; Belongs to the glycosyl hydrolase 56 family. [a.k.a. HYAL1-203, ENST00000457214, U73167]

2) '9606.ENSP00000343366':

VSTM1 - V-set and transmembrane domain-containing protein 1; [Isoform 2]: Behaves as a cytokine, promoting IL17A secretion by CD4+ T-cells, and differentiation and activation of IL17 producing helper T-cells (TH17). [a.k.a. 284415, ENST00000447872.5, V-set and transmembrane domain containing 1]

3) '9606.ENSP00000359630':

ADGRB3 - Adhesion G protein-coupled receptor B3; Receptor that plays a role in the regulation of synaptogenesis and dendritic spine formation at least partly via interaction with ELMO1 and RAC1 activity (By similarity). Promotes myoblast fusion through ELMO/DOCK1. Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily. [a.k.a. 577, UPI00020650A4, ADGRB3-204]

4) '9606.ENSP00000301905':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

5) '9606.ENSP00000358397':

FAM72B - Protein FAM72B; Family with sequence similarity 72 member B; Belongs to the FAM72 family. [a.k.a. ENSP00000347368, ENSP00000482799, URS00008B51B3]

6) '9606.ENSP00000361177':

LRIT1 - Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 1; Possible role in phototransduction. [a.k.a. ENSG00000148602, HGNC:23404, CCDS7373]

7) '9606.ENSP00000379242':

CDRT1 - CMT1A duplicated region transcript 1. [a.k.a. ENSG00000241322, Q9BXD7, ENSP00000486674]

8) '9606.ENSP00000395590':

IFI35 - Interferon-induced 35 kDa protein; Not yet known; Belongs to the NMI family. [a.k.a. uc060fqu.1, AAC37597.1, U72882]

9) '9606.ENSP00000297373':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

10) '9606.ENSP00000398930':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

11) '9606.ENSP00000265056':

MCM2 - DNA replication licensing factor MCM2; Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] [a.k.a. ENSP00000321118, CDCL1, 4171]

12) '9606.ENSP00000301633':

BIRC5 - Baculoviral IAP repeat-containing protein 5; Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis. Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis. Acts as an important regulator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with polymerized microtubules. Involve [...] [a.k.a. R-HSA-2555396, URS00008C14DF, NM_001012270.1]

13) '9606.ENSP00000352835':

MB - Myoglobin; Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles. [a.k.a. ENSP00000352835, NM_203377, ENST00000447607]

14) '9606.ENSP00000375622':

LAIR1 - Leukocyte-associated immunoglobulin-like receptor 1; Functions as an inhibitory receptor that plays a constitutive negative regulatory role on cytolytic function of natural killer (NK) cells, B-cells and T-cells. Activation by Tyr phosphorylation results in recruitment and activation of the phosphatases PTPN6 and PTPN11. It also reduces the increase of intracellular calcium evoked by B-cell receptor ligation. May also play its inhibitory role independently of SH2-containing phosphatases. Modulates cytokine production in CD4+ T- cells, down-regulating IL2 and IFNG production while induc [...] [a.k.a. ENST00000463489, ENSP00000393735, CR542051]

15) '9606.ENSP00000270279':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

16) '9606.ENSP00000446264':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

17) '9606.ENSP00000264651':

KRT24 - Keratin, type I cytoskeletal 24; Keratin 24; Belongs to the intermediate filament family. [a.k.a. keratin 24, CCDS11372.1, XM_011524460]

18) '9606.ENSP00000265748':

ANLN - Anillin; Required for cytokinesis. Essential for the structural integrity of the cleavage furrow and for completion of cleavage furrow ingression. Plays a role in bleb assembly during metaphase and anaphase of mitosis. May play a significant role in podocyte cell migration. [a.k.a. ENSP00000406584, ENSP00000397465, NP_001271231.1]

19) '9606.ENSP00000361298':

KIF2C - Kinesin-like protein KIF2C; In complex with KIF18B, constitutes the major microtubule plus-end depolymerizing activity in mitotic cells. Regulates the turnover of microtubules at the kinetochore and functions in chromosome segregation during mitosis. Plays a role in chromosome congression and is required for the lateral to end- on conversion of the chromosome-microtubule attachment ; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. MCAK/KIF2 subfamily. [a.k.a. R-HSA-2555396, KIF2C-205, R-HSA-69278]

20) '9606.ENSP00000412130':

MRVI1 - Protein MRVI1; Plays a role as NO/PRKG1-dependent regulator of IP3-induced calcium release; its phosphorylation by PRKG1 inhibits bradykinin and IP3-induced calcium release from intracellular stores. Recruits PRKG1 to the endoplasmic reticulum and may mediate the assembly of PRKG1 and ITPR1 in a macrocomplex. Involved in PRKG1 signaling cascade leading to inhibition of platelet activation and aggregation. Mediates also NO- dependent inhibition of calcium signaling in gastrointestinal smooth muscle contributing to NO-dependent relaxation. [a.k.a. B7Z9A3, ENST00000541483.5, ENST00000532037]

101 query items

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