searching ... STRING: functional protein association networks

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The following proteins in Homo sapiens appear to match your input.
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101 query items

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1) '9606.ENSP00000283249':

ITGB6 - Integrin beta-6; Integrin alpha-V:beta-6 (ITGAV:ITGB6) is a receptor for fibronectin and cytotactin. It recognizes the sequence R-G-D in its ligands. Internalisation of integrin alpha-V/beta-6 via clathrin-mediated endocytosis promotes carcinoma cell invasion. ITGAV:ITGB6 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1. Integrin alpha-V:beta-6 (ITGAV:ITGB6) mediates R-G- D-dependent release of transforming growth factor beta-1 (TGF-beta-1) from regulatory Latency-associated peptide (LAP), thereby playing a key role in TGF-beta-1 activation. [...] [a.k.a. R-HSA-2129379, hsa:3694, NP_001269319]

2) '9606.ENSP00000301905':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

3) '9606.ENSP00000385706':

PSG2 - Pregnancy specific beta-1-glycoprotein 2. [a.k.a. R-HSA-202733, BC022316, NM_031246.3]

4) '9606.ENSP00000333196':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

5) '9606.ENSP00000358397':

FAM72B - Protein FAM72B; Family with sequence similarity 72 member B; Belongs to the FAM72 family. [a.k.a. ENSP00000347368, ENSP00000482799, URS00008B51B3]

6) '9606.ENSP00000357753':

IVL - Involucrin; Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia; Belongs to the involucrin family. [a.k.a. INVO_HUMAN, NP_005538.2, CCDS1030.1]

7) '9606.ENSP00000338345':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

8) '9606.ENSP00000349275':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

9) '9606.ENSP00000377502':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

10) '9606.ENSP00000363832':

AOX1 - Aldehyde oxidase; Oxidase with broad substrate specificity, oxidizing aromatic azaheterocycles, such as N1-methylnicotinamide, N-methylphthalazinium and phthalazine, as well as aldehydes, such as benzaldehyde, retinal, pyridoxal, and vanillin. Plays a key role in the metabolism of xenobiotics and drugs containing aromatic azaheterocyclic substituents. Participates in the bioactivation of prodrugs such as famciclovir, catalyzing the oxidation step from 6-deoxypenciclovir to penciclovir, which is a potent antiviral agent. Is probably involved in the regulation of reactive oxygen species [...] [a.k.a. AF009465, Q06278, R-HSA-196854]

11) '9606.ENSP00000442068':

CDCA3 - Cell division cycle-associated protein 3; F-box-like protein which is required for entry into mitosis. Acts by participating in E3 ligase complexes that mediate the ubiquitination and degradation of WEE1 kinase at G2/M phase (By similarity). [a.k.a. URS00008C0C20, D3DUS6, ENST00000538862.6]

12) '9606.ENSP00000274565':

SPINK7 - Serine protease inhibitor Kazal-type 7; Probable serine protease inhibitor. [a.k.a. P58062, uc003lpd.4, SPINK7-204]

13) '9606.ENSP00000450527':

HOPX - Homeodomain-only protein; Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF- dependent cardiac-specific genes and cardiac development. Prevents SRF- dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase (HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy (By similarity). May act as a tumor suppressor. Acts as a co-chaperone for HSPA1A and HSPA1B chaperone protein [...] [a.k.a. NM_139212, ENST00000508121, AAM46832.1]

14) '9606.ENSP00000274276':

OSMR - Oncostatin-M-specific receptor subunit beta; Associates with IL31RA to form the IL31 receptor. Binds IL31 to activate STAT3 and possibly STAT1 and STAT5. Capable of transducing OSM-specific signaling events; Belongs to the type I cytokine receptor family. Type 2 subfamily. [a.k.a. NM_001168355, AAI25210.1, UPI000006DED2]

15) '9606.ENSP00000436580':

PRR23D2 - Proline-rich protein 23D1; Proline rich 23 domain containing 2; Belongs to the PRR23 family. [a.k.a. ENSG00000255378, CCDS64821.1, NM_001282478]

16) '9606.ENSP00000361298':

KIF2C - Kinesin-like protein KIF2C; In complex with KIF18B, constitutes the major microtubule plus-end depolymerizing activity in mitotic cells. Regulates the turnover of microtubules at the kinetochore and functions in chromosome segregation during mitosis. Plays a role in chromosome congression and is required for the lateral to end- on conversion of the chromosome-microtubule attachment ; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. MCAK/KIF2 subfamily. [a.k.a. R-HSA-2555396, KIF2C-205, R-HSA-69278]

17) '9606.ENSP00000383178':

DIAPH3 - Protein diaphanous homolog 3; Actin nucleation and elongation factor required for the assembly of F-actin structures, such as actin cables and stress fibers. Required for cytokinesis, stress fiber formation and transcriptional activation of the serum response factor. Binds to GTP-bound form of Rho and to profilin: acts in a Rho-dependent manner to recruit profilin to the membrane, where it promotes actin polymerization. DFR proteins couple Rho and Src tyrosine kinase during signaling and the regulation of actin dynamics. Also acts as an actin nucleation and elongation factor in the nuc [...] [a.k.a. NX_Q9NSV4, Q86VS4, BC034952]

18) '9606.ENSP00000349145':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

19) '9606.ENSP00000337212':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

20) '9606.ENSP00000249776':

KNSTRN - Small kinetochore-associated protein; Essential component of the mitotic spindle required for faithful chromosome segregation and progression into anaphase. Promotes the metaphase-to-anaphase transition and is required for chromosome alignment, normal timing of sister chromatid segregation, and maintenance of spindle pole architecture. The astrin (SPAG5)-kinastrin (SKAP) complex promotes stable microtubule-kinetochore attachments. Required for kinetochore oscillations and dynamics of microtubule plus-ends during live cell mitosis, possibly by forming a link between spindle microtubule [...] [a.k.a. hsa:90417, H0YLA7, NP_001136233]

101 query items

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