searching ... STRING: functional protein association networks

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The following proteins in Homo sapiens appear to match your input.
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101 query items

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1) '9606.ENSP00000312224':

DTD2 - D-aminoacyl-tRNA deacylase 2; Deacylates mischarged D-aminoacyl-tRNAs (By similarity). Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS (By similarity). Probably acts by rejecting L-amino acids from its binding site rather than specific recognition of D-amino acids (By similarity). Catalyzes the hydrolysis of D-tyrosyl-tRNA(Tyr), has no activity on correctly charged L-tyrosyl- tRNA(Tyr) (By similarity). By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the format [...] [a.k.a. ENST00000549850.1, OTTHUMG00000140205, ENST00000261309]

2) '9606.ENSP00000368682':

PHEX - Phosphate-regulating neutral endopeptidase PHEX; Peptidase that cleaves SIBLING (small integrin-binding ligand, N-linked glycoprotein)-derived ASARM peptides, thus regulating their biological activity. Cleaves ASARM peptides between Ser and Glu or Asp residues. Regulates osteogenic cell differentiation and bone mineralization through the cleavage of the MEPE-derived ASARM peptide. Promotes dentin mineralization and renal phosphate reabsorption by cleaving DMP1- and MEPE-derived ASARM peptides. Inhibits the cleavage of MEPE by CTSB/cathepsin B thus preventing MEPE degradation. [a.k.a. ENSP00000439418, ENSG00000102174, PEX]

3) '9606.ENSP00000261454':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

4) '9606.ENSP00000252809':

GDF15 - Growth/differentiation factor 15; Regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses. Binds to its receptor, GFRAL, and activates GFRAL- expressing neurons localized in the area postrema and nucleus tractus solitarius of the brainstem. It then triggers the activation of neurons localized within the parabrachial nucleus and central amygdala, which contitutes part of the 'emergency circuit' that shapes feeding responses to stressful conditions. On hepatocytes, inhibits growth hormone signaling (By similarity). [a.k.a. CCDS12376.1, BC008962, XM_024451789.1]

5) '9606.ENSP00000369889':

COL2A1 - Collagen alpha-1(II) chain; Type II collagen is specific for cartilaginous tissues. It is essential for the normal embryonic development of the skeleton, for linear growth and for the ability of cartilage to resist compressive forces. [a.k.a. NM_001844, ENSP00000369889, 2FSE]

6) '9606.ENSP00000393887':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

7) '9606.ENSP00000347646':

SOX12 - Transcription factor SOX-12; Binds to the sequence 5'-AACAAT-3'. [a.k.a. ENSP00000441671, NP_008874, NM_006943.3]

8) '9606.ENSP00000321108':

SPOCK2 - Testican-2; May participate in diverse steps of neurogenesis. Binds calcium. [a.k.a. SPOCK2-207, OMIM:607988, testican-2]

9) '9606.ENSP00000265437':

ST7 - Suppressor of tumorigenicity 7 protein; May act as a tumor suppressor; Belongs to the ST7 family. [a.k.a. ENST00000467538, NM_018412.3, NP_001356533]

10) '9606.ENSP00000433352':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

11) '9606.ENSP00000418210':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

12) '9606.ENSP00000226218':

VTN - Vitronectin V10 subunit; Vitronectin is a cell adhesion and spreading factor found in serum and tissues. Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway. [a.k.a. R-HSA-2129379, ENST00000539746.1, V75]

13) '9606.ENSP00000336831':

PLS1 - Plastin-1; Actin-bundling protein in the absence of calcium. [a.k.a. XP_016862115, XP_011511202.1, ENST00000483507.1]

14) '9606.ENSP00000257555':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

15) '9606.ENSP00000313681':

SPHK1 - Sphingosine kinase 1; Catalyzes the phosphorylation of sphingosine to form sphingosine 1-phosphate (SPP), a lipid mediator with both intra- and extracellular functions. Also acts on D-erythro-sphingosine and to a lesser extent sphinganine, but not other lipids, such as D,L-threo- dihydrosphingosine, N,N-dimethylsphingosine, diacylglycerol, ceramide, or phosphatidylinositol. In contrast to proapoptotic SPHK2, has a negative effect on intracellular ceramide levels, enhances cell growth and inhibits apoptosis. Involved in the regulation of inflammatory response and neuroinflammation. Via [...] [a.k.a. AF266756, ENSP00000465726, uc002jrf.1]

16) '9606.ENSP00000225740':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

17) '9606.ENSP00000363435':

ITPR3 - Inositol 1,4,5-trisphosphate receptor type 3; Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium. [a.k.a. R-HSA-388396, R-HSA-9006925, inositol 1,4,5-trisphosphate receptor type 3]

18) '9606.ENSP00000329471':

KDELR1 - ER lumen protein-retaining receptor 1; Receptor for the C-terminal sequence motif K-D-E-L that is present on endoplasmic reticulum resident proteins and that mediates their recycling from the Golgi back to the endoplasmic reticulum. Belongs to the ERD2 family. [a.k.a. P24390, R-HSA-6811442, X55885]

19) '9606.ENSP00000365227':

AIF1 - Allograft inflammatory factor 1; Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation. [a.k.a. ENST00000376059, AAA92457.1, XM_017010332]

20) '9606.ENSP00000369695':

MLLT3 - Protein AF-9; Chromatin reader component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. Specifically recognizes and binds acylated histone H3, with a marked preference for histone H3 that is crotonylated. Crotonylation marks active promoters and enhancers and confers resistance to transcriptional repressors. Recognizes and binds histone H3 crotonylated at 'Lys-9' (H3K9cr), and with slightly lower affinity histone H3 crotonylate [...] [a.k.a. 2LM0, 5YYF, ENST00000380321]

101 query items

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