searching ... STRING: functional protein association networks

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The following proteins in Homo sapiens appear to match your input.
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95 query items

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1) '9606.ENSP00000312625':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

2) '9606.ENSP00000249501':

HOXD10 - Homeobox protein Hox-D10; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. [a.k.a. URS0000EB4C6A, X59373, HOX4D]

3) '9606.ENSP00000380888':

MED13 - Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. [a.k.a. TRAP240, THRAP1, 9969]

4) '9606.ENSP00000261349':

LRP6 - Low-density lipoprotein receptor-related protein 6; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Cell-surface coreceptor of Wnt/beta-catenin signaling, which plays a pivotal role in bone formation. The Wnt-induced Fzd/LRP6 coreceptor complex recruits DVL1 polymers to the plasma membrane which, in turn, recruits the AXIN1/GSK3B-complex to the cell surface promoting the formation of signalsomes and inhibiting AXIN1/GSK3-mediated phosphorylation and destruction of [...] [a.k.a. ENST00000261349.8, R-HSA-162582, R-HSA-4641263]

5) '9606.ENSP00000369500':

SYAP1 - Synapse-associated protein 1; Plays a role in adipocyte differentiation by promoting mTORC2-mediated phosphorylation of AKT1 at 'Ser-473' after growth factor stimulation. [a.k.a. HPA048047, CCDS14177.1, CAH18697.1]

6) '9606.ENSP00000374565':

FAM168B - Myelin-associated neurite-outgrowth inhibitor; Inhibitor of neuronal axonal outgrowth. Acts as a negative regulator of CDC42 and STAT3 and a positive regulator of STMN2. Positive regulator of CDC27. [a.k.a. Q6NZ40, NP_001009993.2, NP_001308672.1]

7) '9606.ENSP00000312837':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

8) '9606.ENSP00000434034':

FZD4 - Frizzled-4; Receptor for Wnt proteins. Most frizzled receptors are coupled to the beta-catenin (CTNNB1) canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin (CTNNB1) and activation of Wnt target genes. Plays a critical role in retinal vascularization by acting as a receptor for Wnt proteins and norrin (NDP) (By similarity). In retina, it can be activated by Wnt protein-binding and also by Wnt-independent signaling via binding of norrin (NDP), promoting in both cases beta-catenin (CTNNB1) accu [...] [a.k.a. frizzled homolog 4 (Drosophila), FzE4, frizzled (Drosophila) homolog 4]

9) '9606.ENSP00000438284':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

10) '9606.ENSP00000354742':

IPO9 - Importin-9; Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran- dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis re [...] [a.k.a. CCDS1415, AK001264, ENST00000479374.1]

11) '9606.ENSP00000438346':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

12) '9606.ENSP00000397644':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

13) '9606.ENSP00000384889':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

14) '9606.ENSP00000358297':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

15) '9606.ENSP00000306473':

SHCBP1 - SHC SH2 domain-binding protein 1; May play a role in signaling pathways governing cellular proliferation, cell growth and differentiation. May be a component of a novel signaling pathway downstream of Shc. Acts as a positive regulator of FGF signaling in neural progenitor cells. [a.k.a. URS0000E97C7F, NP_001311247, SHCBP1-206]

16) '9606.ENSP00000327213':

NRIP1 - Nuclear receptor-interacting protein 1; Modulates transcriptional activation by steroid receptors such as NR3C1, NR3C2 and ESR1. Also modulates transcriptional repression by nuclear hormone receptors. Positive regulator of the circadian clock gene expression: stimulates transcription of ARNTL/BMAL1, CLOCK and CRY1 by acting as a coactivator for RORA and RORC. Involved in the regulation of ovarian function (By similarity). Plays a role in renal development. [a.k.a. ENST00000637630.1, RIP140, AAH40361.1]

17) '9606.ENSP00000423600':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

18) '9606.ENSP00000369460':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

19) '9606.ENSP00000359635':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

20) '9606.ENSP00000380692':

KDM7A - Lysine-specific demethylase 7A; Histone demethylase required for brain development. Specifically demethylates dimethylated 'Lys-9' and 'Lys-27' (H3K9me2 and H3K27me2, respectively) of histone H3 and monomethylated histone H4 'Lys-20' residue (H4K20Me1), thereby playing a central role in histone code. Specifically binds trimethylated 'Lys-4' of histone H3 (H3K4me3), affecting histone demethylase specificity: in presence of H3K4me3, it has no demethylase activity toward H3K9me2, while it has high activity toward H3K27me2. Demethylates H3K9me2 in absence of H3K4me3. Has activity toward H4 [...] [a.k.a. NM_030647.2, XP_011514889.1, KDM7A-203]

95 query items

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