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The following proteins in
Homo sapiens
appear to match your input.
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101 query items
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1) '9606.ENSP00000337354':
LIPA - Lysosomal acid lipase/cholesteryl ester hydrolase; Crucial for the intracellular hydrolysis of cholesteryl esters and triglycerides that have been internalized via receptor- mediated endocytosis of lipoprotein particles. Important in mediating the effect of LDL (low density lipoprotein) uptake on suppression of hydroxymethylglutaryl-CoA reductase and activation of endogenous cellular cholesteryl ester formation; Belongs to the AB hydrolase superfamily. Lipase family.
[a.k.a. U04291, NP_000226.2, CCDS7401.1]
2) '9606.ENSP00000359567':
SOX3 - Transcription factor SOX-3; Transcription factor required during the formation of the hypothalamo-pituitary axis. May function as a switch in neuronal development. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation. Required also within the pharyngeal epithelia for craniofacial morphogenesis. Controls a genetic switch in male development. Is necessary for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells (By s [...]
[a.k.a. HPA075003, R-HSA-162582, R-HSA-195721]
3) '9606.ENSP00000407509':
PNPLA6 - Neuropathy target esterase; Phospholipase B that deacylates intracellular phosphatidylcholine (PtdCho), generating glycerophosphocholine (GroPtdCho). This deacylation occurs at both sn-2 and sn-1 positions of PtdCho. Its specific chemical modification by certain organophosphorus (OP) compounds leads to distal axonopathy.
[a.k.a. ENSP00000394348, UPI0007699E5F, R-HSA-1483255]
4) '9606.ENSP00000368699':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
5) '9606.ENSP00000356591':
SOAT1 - Sterol O-acyltransferase 1; Catalyzes the formation of fatty acid-cholesterol esters, which are less soluble in membranes than cholesterol. Plays a role in lipoprotein assembly and dietary cholesterol absorption. In addition to its acyltransferase activity, it may act as a ligase.
[a.k.a. CCDS58047, ENSG00000057252, STAT]
6) '9606.ENSP00000323805':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
7) '9606.ENSP00000380646':
TMEM80 - Transmembrane protein 80.
[a.k.a. EAX02373.1, ENST00000397510, ENSP00000320678]
8) '9606.ENSP00000287156':
UBE2L6 - Ubiquitin/ISG15-conjugating enzyme E2 L6; Catalyzes the covalent attachment of ubiquitin or ISG15 to other proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Promotes ubiquitination and subsequent proteasomal degradation of FLT3.
[a.k.a. ubiquitin-conjugating enzyme E2L 6, CAB073407, 1WZW]
9) '9606.ENSP00000353475':
CLDN7 - Claudin-7; Plays a major role in tight junction-specific obliteration of the intercellular space; Belongs to the claudin family.
[a.k.a. ENST00000573745, ENST00000538261, AAP97219.1]
10) '9606.ENSP00000289749':
NBL1 - Neuroblastoma suppressor of tumorigenicity 1; Possible candidate as a tumor suppressor gene of neuroblastoma. May play an important role in preventing cells from entering the final stage (G1/S) of the transformation process; Belongs to the DAN family.
[a.k.a. MICOS10-NBL1, A3KFI5, D28124]
11) '9606.ENSP00000254043':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
12) '9606.ENSP00000378400':
LIMA1 - LIM domain and actin-binding protein 1; Actin-binding protein involved in actin cytoskeleton regulation and dynamics. Increases the number and size of actin stress fibers and inhibits membrane ruffling. Inhibits actin filament depolymerization. Bundles actin filaments, delays filament nucleation and reduces formation of branched filaments. Plays a role in cholesterol homeostasis. Influences plasma cholesterol levels through regulation of intestinal cholesterol absorption. May act as a scaffold protein by regulating NPC1L1 transportation, an essential protein for cholesterol absorption, [...]
[a.k.a. uc001rwg.5, AF157325, BAA90914.1]
13) '9606.ENSP00000268720':
CPNE7 - Copine-7; Calcium-dependent phospholipid-binding protein that may play a role in calcium-mediated intracellular processes. Belongs to the copine family.
[a.k.a. CPNE7-206, XM_017023141, R-HSA-556833]
14) '9606.ENSP00000378856':
LGALS9 - Galectin-9; Binds galactosides. Has high affinity for the Forssman pentasaccharide. Ligand for HAVCR2/TIM3. Binding to HAVCR2 induces T-helper type 1 lymphocyte (Th1) death. Also stimulates bactericidal activity in infected macrophages by causing macrophage activation and IL1B secretion which restricts intracellular bacterial growth (By similarity). Ligand for P4HB; the interaction retains P4HB at the cell surface of Th2 T-helper cells, increasing disulfide reductase activity at the plasma membrane, altering the plasma membrane redox state and enhancing cell migration. Ligand for CD44; [...]
[a.k.a. ENST00000579930, XP_006721956, ENST00000395473.6]
15) '9606.ENSP00000278937':
MPZL2 - Myelin protein zero-like protein 2; Mediates homophilic cell-cell adhesion.
[a.k.a. MPZL2-206, NM_005797, uc001psn.4]
16) '9606.ENSP00000228928':
OAS3 - 2'-5'-oligoadenylate synthase 3; Interferon-induced, dsRNA-activated antiviral enzyme which plays a critical role in cellular innate antiviral response. In addition, it may also play a role in other cellular processes such as apoptosis, cell growth, differentiation and gene regulation. Synthesizes preferentially dimers of 2'-5'-oligoadenylates (2-5A) from ATP which then bind to the inactive monomeric form of ribonuclease L (RNase L) leading to its dimerization and subsequent activation. Activation of RNase L leads to degradation of cellular as well as viral RNA, resulting in the inhibi [...]
[a.k.a. AF063613, Q9Y6K5, R-HSA-8983711]
17) '9606.ENSP00000362441':
ATRX - Transcriptional regulator ATRX; Involved in transcriptional regulation and chromatin remodeling. Facilitates DNA replication in multiple cellular environments and is required for efficient replication of a subset of genomic loci. Binds to DNA tandem repeat sequences in both telomeres and euchromatin and in vitro binds DNA quadruplex structures. May help stabilizing G-rich regions into regular chromatin structures by remodeling G4 DNA and incorporating H3.3-containing nucleosomes. Catalytic component of the chromatin remodeling complex ATRX:DAXX which has ATP-dependent DNA translocase a [...]
[a.k.a. ATRX-209, ENST00000622960.1, ENST00000493470.2]
18) '9606.ENSP00000290524':
RFX5 - DNA-binding protein RFX5; Activates transcription from class II MHC promoters. Recognizes X-boxes. Mediates cooperative binding between RFX and NF-Y. RFX binds the X1 box of MHC-II promoters; Belongs to the RFX family.
[a.k.a. XP_011508150.1, ENST00000478564, ENSP00000396810]
19) '9606.ENSP00000298902':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
20) '9606.ENSP00000399985':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
101 query items
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