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The following proteins in
Homo sapiens
appear to match your input.
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101 query items
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1) '9606.ENSP00000342805':
FAIM - Fas apoptotic inhibitory molecule 1; Plays a role as an inducible effector molecule that mediates Fas resistance produced by surface Ig engagement in B cells. Belongs to the FAIM1 family.
[a.k.a. FAIM-206, ENSP00000342805, ENST00000479848.1]
2) '9606.ENSP00000403400':
CCPG1 - Cell cycle progression protein 1; Acts as an assembly platform for Rho protein signaling complexes. Limits guanine nucleotide exchange activity of MCF2L toward RHOA, which results in an inhibition of both its transcriptional activation ability and its transforming activity. Does not inhibit activity of MCF2L toward CDC42, or activity of MCF2 toward either RHOA or CDC42 (By similarity). May be involved in cell cycle regulation. Belongs to the CCPG1 family.
[a.k.a. ENST00000563171, ENST00000564663, CCDS55966.1]
3) '9606.ENSP00000288462':
C9orf43 - Uncharacterized protein C9orf43; Chromosome 9 open reading frame 43.
[a.k.a. ENSP00000288462, ENSG00000157653, 257169]
4) '9606.ENSP00000212355':
TGFBR3 - Transforming growth factor beta receptor type 3; Binds to TGF-beta. Could be involved in capturing and retaining TGF-beta for presentation to the signaling receptors.
[a.k.a. OMIM:600742, BGCAN, OTTHUMG00000010097]
5) '9606.ENSP00000246549':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
6) '9606.ENSP00000264433':
FNIP2 - Folliculin-interacting protein 2; Acts as a co-chaperone of HSP90AA1. Inhibits the ATPase activity of HSP90AA1 leading to reduction in its chaperone activity. Facilitates the binding of client protein FLCN to HSP90AA1. May play a role in the signal transduction pathway of apoptosis induced by O6-methylguanine-mispaired lesions (By similarity). May be involved in energy and/or nutrient sensing through the AMPK and mTOR signaling pathways. May regulate phosphorylation of RPS6KB1.
[a.k.a. KIAA1450, NP_001332972.1, ENST00000505445.1]
7) '9606.ENSP00000354813':
MT-ND5 - NADH-ubiquinone oxidoreductase chain 5; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
[a.k.a. ND5, ASS17972.1, KJ446191]
8) '9606.ENSP00000340749':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
9) '9606.ENSP00000263925':
LNX1 - E3 ubiquitin-protein ligase LNX; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of NUMB. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates ubiquitination of isoform p66 and isoform p72 of NUMB, but not that of isoform p71 or isoform p65.
[a.k.a. XM_017008776, XM_024454261.1, CCDS3492.1]
10) '9606.ENSP00000295240':
BBS5 - Bardet-Biedl syndrome 5 protein; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl ex [...]
[a.k.a. Bardet-Biedl syndrome 5, NX_Q8N3I7, ENSP00000413021]
11) '9606.ENSP00000395590':
IFI35 - Interferon-induced 35 kDa protein; Not yet known; Belongs to the NMI family.
[a.k.a. uc060fqu.1, AAC37597.1, U72882]
12) '9606.ENSP00000261196':
SLCO1B3 - Solute carrier organic anion transporter family member 1B3; Mediates the Na(+)-independent uptake of organic anions such as 17-beta-glucuronosyl estradiol, taurocholate, triiodothyronine (T3), leukotriene C4, dehydroepiandrosterone sulfate (DHEAS), methotrexate and sulfobromophthalein (BSP). Involved in the clearance of bile acids and organic anions from the liver; Belongs to the organo anion transporter (TC 2.A.60) family.
[a.k.a. NX_Q9NPD5, ENST00000544370, ENST00000545880]
13) '9606.ENSP00000250173':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
14) '9606.ENSP00000441269':
ENSP00000441269 - Solute carrier organic anion transporter family member; SLCO1B3-SLCO1B7 readthrough.
[a.k.a. SLCO1B3-SLCO1B7, F5H094, HGNC:54403]
15) '9606.ENSP00000335153':
HSP90AA1 - Heat shock protein HSP 90-alpha; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a ra [...]
[a.k.a. R-HSA-1643713, R-HSA-196854, ENSP00000216281]
16) '9606.ENSP00000291539':
PDE9A - High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A; Specifically hydrolyzes the second messenger cGMP, which is a key regulator of many important physiological processes. Highly specific: compared to other members of the cyclic nucleotide phosphodiesterase family, has the highest affinity and selectivity for cGMP. Specifically regulates natriuretic-peptide-dependent cGMP signaling in heart, acting as a regulator of cardiac hypertrophy in myocytes and muscle. Does not regulate nitric oxide-dependent cGMP in heart. Additional experiments are required to confirm whether its abi [...]
[a.k.a. NM_001001578.1, ENST00000398227, ENST00000328862]
17) '9606.ENSP00000327889':
INTS5 - Integrator complex subunit 5; Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex.
[a.k.a. R-HSA-6807505, Integrator complex subunit 5, Q8N6W5]
18) '9606.ENSP00000253048':
ZC3H4 - Zinc finger CCCH-type containing 4.
[a.k.a. NM_015168.2, NM_015168.1, XM_011526670]
19) '9606.ENSP00000251507':
RABGAP1L - Rab GTPase-activating protein 1-like; GTP-hydrolysis activating protein (GAP) for small GTPase RAB22A, converting active RAB22A-GTP to the inactive form RAB22A-GDP. Plays a role in endocytosis and intracellular protein transport. Recruited by ANK2 to phosphatidylinositol 3- phosphate (PI3P)-positive early endosomes, where it inactivates RAB22A, and promotes polarized trafficking to the leading edge of the migrating cells. Part of the ANK2/RABGAP1L complex which is required for the polarized recycling of fibronectin receptor ITGA5 ITGB1 to the plasma membrane that enables continuous dir [...]
[a.k.a. A0A0C4DG54, ENST00000457696, CAI18933.1]
20) '9606.ENSP00000270747':
ARHGEF19 - Rho guanine nucleotide exchange factor 19; Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase.
[a.k.a. R-HSA-388396, NP_694945.2, R-HSA-162582]
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