searching ... STRING: functional protein association networks

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The following proteins in Homo sapiens appear to match your input.
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101 query items

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1) '9606.ENSP00000361467':

DLG5 - Disks large homolog 5; Acts as a regulator of the Hippo signaling pathway. Negatively regulates the Hippo signaling pathway by mediating the interaction of MARK3 with STK3/4, bringing them together to promote MARK3-dependent hyperphosphorylation and inactivation of STK3 kinase activity toward LATS1. Positively regulates the Hippo signaling pathway by mediating the interaction of SCRIB with STK4/MST1 and LATS1 which is important for the activation of the Hippo signaling pathway. Involved in regulating cell proliferation, maintenance of epithelial polarity, epithelial-mesenchymal transit [...] [a.k.a. NX_Q8TDM6, Discs large MAGUK scaffold protein 5, ENST00000320558]

2) '9606.ENSP00000262126':

ANKRD12 - Ankyrin repeat domain-containing protein 12; May recruit HDACs to the p160 coactivators/nuclear receptor complex to inhibit ligand-dependent transactivation. [a.k.a. NP_056023.3, NM_001204056, XP_016881159]

3) '9606.ENSP00000225388':

NUFIP2 - Nuclear fragile X mental retardation-interacting protein 2; Binds RNA. [a.k.a. FMRP-interacting protein 2, NM_020772, BC129990]

4) '9606.ENSP00000295984':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

5) '9606.ENSP00000285947':

SETD9 - SET domain containing 9. [a.k.a. ENST00000477359.1, Q8NE22, UPI00004140D4]

6) '9606.ENSP00000342148':

TMEM167B - Protein kish-B; Involved in the early part of the secretory pathway. Belongs to the KISH family. [a.k.a. NM_020141, URS00008C220A, Transmembrane protein 167B]

7) '9606.ENSP00000452959':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

8) '9606.ENSP00000010299':

FAM76A - Protein FAM76A; Family with sequence similarity 76 member A. [a.k.a. NP_001137387, ENST00000234549, OTTHUMG00000003729]

9) '9606.ENSP00000257749':

BACH2 - Transcription regulator protein BACH2; Transcriptional regulator that acts as repressor or activator (By similarity). Binds to Maf recognition elements (MARE) (By similarity). Plays an important role in coordinating transcription activation and repression by MAFK (By similarity). Induces apoptosis in response to oxidative stress through repression of the antiapoptotic factor HMOX1. Positively regulates the nuclear import of actin (By similarity). Is a key regulator of adaptive immunity, crucial for the maintenance of regulatory T-cell function and B-cell maturation ; Belongs to the bZI [...] [a.k.a. ENST00000470301.5, ENSP00000345642, NM_021813]

10) '9606.ENSP00000384198':

INO80D - INO80 complex subunit D; Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. [a.k.a. 54891, XM_011511376, BC004193]

11) '9606.ENSP00000290158':

KPNB1 - Importin subunit beta-1; Functions in nuclear protein import, either in association with an adapter protein, like an importin-alpha subunit, which binds to nuclear localization signals (NLS) in cargo substrates, or by acting as autonomous nuclear transport receptor. Acting autonomously, serves itself as NLS receptor. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic [...] [a.k.a. NP_001263382.1, CAB034449, HPA050302]

12) '9606.ENSP00000451320':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

13) '9606.ENSP00000299293':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

14) '9606.ENSP00000250405':

BCL2L2 - Bcl-2-like protein 2; Promotes cell survival. Blocks dexamethasone-induced apoptosis. Mediates survival of postmitotic Sertoli cells by suppressing death-promoting activity of BAX. [a.k.a. ENSP00000250405, BC011637, UPI00021CF243]

15) '9606.ENSP00000320447':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

16) '9606.ENSP00000341171':

MTSS2 - Protein MTSS 2; Involved in plasma membrane dynamics. Potentiated PDGF- mediated formation of membrane ruffles and lamellipodia in fibroblasts, acting via RAC1 activation. May function in actin bundling ; Belongs to the MTSS family. [a.k.a. OTTHUMG00000177023, ENST00000254951, NM_138383]

17) '9606.ENSP00000354398':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

18) '9606.ENSP00000282397':

FLT1 - Vascular endothelial growth factor receptor 1; Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFB and PGF, and plays an essential role in the development of embryonic vasculature, the regulation of angiogenesis, cell survival, cell migration, macrophage function, chemotaxis, and cancer cell invasion. May play an essential role as a negative regulator of embryonic angiogenesis by inhibiting excessive proliferation of endothelial cells. Can promote endothelial cell proliferation, survival and angiogenesis in adulthood. Its function in promoting cell proliferati [...] [a.k.a. ENSP00000443311, ACF47597.1, 4CL7]

19) '9606.ENSP00000380781':

NFIX - Nuclear factor 1 X-type; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication; Belongs to the CTF/NF-I family. [a.k.a. K7ESG9, AAD38240.1, NP_001257972.1]

20) '9606.ENSP00000256509':

CHL1 - Processed neural cell adhesion molecule L1-like protein; Extracellular matrix and cell adhesion protein that plays a role in nervous system development and in synaptic plasticity. Both soluble and membranous forms promote neurite outgrowth of cerebellar and hippocampal neurons and suppress neuronal cell death. Plays a role in neuronal positioning of pyramidal neurons and in regulation of both the number of interneurons and the efficacy of GABAergic synapses. May play a role in regulating cell migration in nerve regeneration and cortical development. Potentiates integrin-dependent cell [...] [a.k.a. XM_011533292.1, XP_016861060.1, Q59FY0]

101 query items

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