searching ... STRING: functional protein association networks

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The following proteins in Homo sapiens appear to match your input.
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101 query items

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1) '9606.ENSP00000378577':

CLDN3 - Claudin-3; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. [a.k.a. NP_001297.1, claudin 3, Q75L79]

2) '9606.ENSP00000358965':

C1orf194 - Protein C1orf194; May play an important role for the maintenance of myelin-axon integrity (By similarity). May affect intracellular Ca(2+) homeostasis. [a.k.a. XP_011538949, ENST00000317648, BM726900]

3) '9606.ENSP00000318615':

TRIM73 - Tripartite motif containing 73; Belongs to the TRIM/RBCC family. [a.k.a. AF498998, Q86UV7, Tripartite motif-containing protein 50B]

4) '9606.ENSP00000252506':

GADD45G - Growth arrest and DNA damage-inducible protein GADD45 gamma; Involved in the regulation of growth and apoptosis. Mediates activation of stress-responsive MTK1/MEKK4 MAPKKK; Belongs to the GADD45 family. [a.k.a. growth arrest and DNA damage inducible gamma, ENST00000494726.1, AF079806]

5) '9606.ENSP00000452959':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

6) '9606.ENSP00000420716':

ARMH1 - Armadillo like helical domain containing 1. [a.k.a. ENSP00000420716, XP_011539643, 339541]

7) '9606.ENSP00000270115':

LRRC56 - Leucine-rich repeat-containing protein 56; Required for the assembly of dynein arms. Belongs to the LRRC56 family. [a.k.a. XM_011519875.2, CCDS7700, XP_011518177.1]

8) '9606.ENSP00000353868':

PCED1A - PC-esterase domain containing 1A; Belongs to the PC-esterase family. [a.k.a. Q9H6D1, PCED1A-202, XP_005260863]

9) '9606.ENSP00000318861':

SF3B2 - Splicing factor 3B subunit 2; Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex. SF3B complex is required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex. Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron. [a.k.a. SF3b145, AK290850, SF3B2-202]

10) '9606.ENSP00000267807':

ZNF280D - Zinc finger protein 280D; May function as a transcription factor. [a.k.a. ZNF280D-205, A1L495, ENST00000560002]

11) '9606.ENSP00000361777':

SET - Protein SET; Multitasking protein, involved in apoptosis, transcription, nucleosome assembly and histone chaperoning. Isoform 2 anti-apoptotic activity is mediated by inhibition of the GZMA-activated DNase, NME1. In the course of cytotoxic T-lymphocyte (CTL)-induced apoptosis, GZMA cleaves SET, disrupting its binding to NME1 and releasing NME1 inhibition. Isoform 1 and isoform 2 are potent inhibitors of protein phosphatase 2A. Isoform 1 and isoform 2 inhibit EP300/CREBBP and PCAF- mediated acetylation of histones (HAT) and nucleosomes, most probably by masking the accessibility of lysi [...] [a.k.a. HPA063683, CAG38780.1, NM_001248000.1]

12) '9606.ENSP00000290155':

CFAP298 - Cilia- and flagella-associated protein 298; Plays a role in motile cilium function, possibly by acting on outer dynein arm assembly. Seems to be important for initiation rather than maintenance of cilium motility (By similarity). Required for correct positioning of the cilium at the apical cell surface, suggesting an additional role in the planar cell polarity (PCP) pathway (By similarity). May suppress canonical Wnt signaling activity (By similarity); Belongs to the CFAP298 family. [a.k.a. ENSP00000441115, ENSP00000333814, CH471079]

13) '9606.ENSP00000283645':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

14) '9606.ENSP00000315505':

ZNF875 - Zinc finger protein 875; May be involved in transcriptional regulation. [a.k.a. ENST00000587829, XM_017026674, NM_001329775]

15) '9606.ENSP00000354028':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

16) '9606.ENSP00000420927':

PDK2 - [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial; Kinase that plays a key role in the regulation of glucose and fatty acid metabolism and homeostasis via phosphorylation of the pyruvate dehydrogenase subunits PDHA1 and PDHA2. This inhibits pyruvate dehydrogenase activity, and thereby regulates metabolite flux through the tricarboxylic acid cycle, down-regulates aerobic respiration and inhibits the formation of acetyl-coenzyme A from pyruvate. Inhibition of pyruvate dehydrogenase decreases glucose utilization and increases fat metabolism. Mediates cellular [...] [a.k.a. 5164, Pyruvate dehydrogenase kinase 2, ENST00000503614]

17) '9606.ENSP00000313833':

LCN15 - Lipocalin-15; Lipocalin 15. [a.k.a. NP_976222.1, R-HSA-804914, 389812]

18) '9606.ENSP00000304355':

CCDC126 - Coiled-coil domain containing 126. [a.k.a. CCDC126-202, coiled-coil domain containing 126, ENST00000484553]

19) '9606.ENSP00000341208':

STAT5A - Signal transducer and activator of transcription 5A; Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Mediates cellular responses to ERBB4. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the GAS element and activates PRL- induced transcription. Regulates the expression of milk proteins during lactation. [a.k.a. STAT5, R-HSA-1226099, R-HSA-162582]

20) '9606.ENSP00000258484':

EPC2 - Enhancer of polycomb homolog 2; May play a role in transcription or DNA repair. Belongs to the enhancer of polycomb family. [a.k.a. NP_056445, ENSP00000258484, UPI00018816FD]

101 query items

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