searching ... STRING: functional protein association networks

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The following proteins in Homo sapiens appear to match your input.
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101 query items

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1) '9606.ENSP00000382707':

IFITM3 - Interferon-induced transmembrane protein 3; IFN-induced antiviral protein which disrupts intracellular cholesterol homeostasis. Inhibits the entry of viruses to the host cell cytoplasm by preventing viral fusion with cholesterol depleted endosomes. May inactivate new enveloped viruses which buds out of the infected cell, by letting them go out with a cholesterol depleted membrane. Active against multiple viruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV) and Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV), human immunodeficiency virus [...] [a.k.a. AFF60337.1, Q53Y76, AFF60339.1]

2) '9606.ENSP00000363993':

PSMB9 - Proteasome subunit beta type-9; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides. Replacement of PSMB6 by PSMB9 increases the capacity of the immunoproteasome to cleave model peptides after hydrophobic and basic residues. [a.k.a. ENST00000395330, R-HSA-2555396, CAB015180]

3) '9606.ENSP00000209875':

CBX5 - Chromobox protein homolog 5; Component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when 'Tyr-41' of histone H3 is phosphorylated (H3Y41ph). Can interact with lamin-B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins. [a.k.a. AAA72327.1, HP1 alpha homolog (Drosophila), R-HSA-2990846]

4) '9606.ENSP00000379458':

ZNF586 - Zinc finger protein 586; May be involved in transcriptional regulation. [a.k.a. ENST00000598885, AK095993, ENST00000449441]

5) '9606.ENSP00000351259':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

6) '9606.ENSP00000264233':

POLQ - DNA polymerase theta; DNA polymerase that promotes microhomology-mediated end- joining (MMEJ), an alternative non-homologous end-joining (NHEJ) machinery triggered in response to double-strand breaks in DNA. MMEJ is an error-prone repair pathway that produces deletions of sequences from the strand being repaired and promotes genomic rearrangements, such as telomere fusions, some of them leading to cellular transformation. POLQ acts as an inhibitor of homology-recombination repair (HR) pathway by limiting RAD51 accumulation at resected ends. POLQ-mediated MMEJ may be required to promote [...] [a.k.a. URS0000EB76BA, 4X0P, NP_955452]

7) '9606.ENSP00000331471':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

8) '9606.ENSP00000241436':

POLK - DNA polymerase kappa; DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high-fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Depending on the context, it inserts the correct base, but causes frequent base transitions, transversions and frameshifts. Lacks 3'-5' proofreading exonuclease activity. Forms a Schiff base with 5'-deoxyribose phosphate at abasic sites, but does not have lyase activity. Belongs to the DNA polymerase type-Y family. [a.k.a. AAN15780.1, ENST00000514141, ENST00000505975.5]

9) '9606.ENSP00000382592':

KRTAP5-3 - Keratin associated protein 5-3. [a.k.a. ENST00000435392, KRTAP5-9, CCDS41591]

10) '9606.ENSP00000431443':

KRTAP5-9 - Keratin associated protein 5-9. [a.k.a. KRTAP5-1, R-HSA-6805567, AAH69531.1]

11) '9606.ENSP00000332511':

OLFML1 - Olfactomedin-like protein 1; Olfactomedin like 1. [a.k.a. NX_Q6UWY5, ENST00000530135, BC035895]

12) '9606.ENSP00000230568':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

13) '9606.ENSP00000316772':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

14) '9606.ENSP00000364864':

KIF3B - Kinesin-like protein KIF3B, N-terminally processed; Involved in tethering the chromosomes to the spindle pole and in chromosome movement. Microtubule-based anterograde translocator for membranous organelles. Plus end-directed microtubule sliding activity in vitro (By similarity). [a.k.a. ENSG00000101350, AB002357, R-HSA-6811442]

15) '9606.ENSP00000355955':

NENF - Neudesin; Acts as a neurotrophic factor in postnatal mature neurons enhancing neuronal survival. Promotes cell proliferation and neurogenesis in undifferentiated neural progenitor cells at the embryonic stage and inhibits differentiation of astrocytes (By similarity). Its neurotrophic activity is exerted via MAPK1/ERK2, MAPK3/ERK1 and AKT1/AKT pathways (By similarity). Neurotrophic activity is enhanced by binding to heme (By similarity). Acts also as an anorexigenic neurotrophic factor that contributes to energy balance (By similarity). [a.k.a. NENF-204, NENF-201, A1KYQ8]

16) '9606.ENSP00000431254':

IGLL5 - Immunoglobulin lambda like polypeptide 5. [a.k.a. 100423062, NP_001243225.1, ENSP00000480519]

17) '9606.ENSP00000351473':

GIMAP5 - GTPase IMAP family member 5; Plays a role in T lymphocyte development and the optimal generation of CD4/CD8 double-positive thymocytes (By similarity). Inhibitor of GSK3A, possibly by sequestering GSK3A in cytoplasmic vesicles and impairing its translocation to the nucleus. Consequently, impairs GSK3A-dependent transcriptional program and regulation of the DNA damage response occurring during T cells proliferation. Required for the survival of peripheral T cells, natural killer (NK) and NK T-cell development and the maintenance of normal liver function (By similarity). May promote the [...] [a.k.a. AAH11732.1, EAW54092.1, AK002158]

18) '9606.ENSP00000324343':

UPB1 - Beta-ureidopropionase; Catalyzes a late step in pyrimidine degradation. Converts N-carbamoyl-beta-alanine (3-ureidopropanoate) into beta-alanine, ammonia and carbon dioxide. Likewise, converts N-carbamoyl-beta- aminoisobutyrate (3-ureidoisobutyrate) into beta-aminoisobutyrate, ammonia and carbon dioxide (Probable). Belongs to the carbon-nitrogen hydrolase superfamily. BUP family. [a.k.a. AF169555, AF169556, UPI0000401FD2]

19) '9606.ENSP00000365775':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

20) '9606.ENSP00000365048':

TNFSF13B - Tumor necrosis factor ligand superfamily member 13b, membrane form; Cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA. TNFSF13/APRIL binds to the same 2 receptors. Together, they form a 2 ligands -2 receptors pathway involved in the stimulation of B- and T- cell function and the regulation of humoral immunity. A third B-cell specific BAFF-receptor (BAFFR/BR3) promotes the survival of mature B- cells and the B-cell response. [Isoform 3]: Acts as a transcription factor for its own parent gene, in association with NF-kappa-B p50 subunit, at least in autoimmune and proliferative B-ce [...] [a.k.a. ENST00000493765, UPI0000001C02, NM_006573.4]

101 query items

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