searching ... STRING: functional protein association networks

Version:
12.0

The following proteins in Homo sapiens appear to match your input.
Please review the list, then click 'Continue' to proceed.

<- Back ⤓ Mapping Continue ->

101 query items

showing page 1 of 6 • first • previous • next • last

1) '9606.ENSP00000398824':

PHF21A - PHD finger protein 21A; Component of the BHC complex, a corepressor complex that represses transcription of neuron-specific genes in non-neuronal cells. The BHC complex is recruited at RE1/NRSE sites by REST and acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier. In the BHC complex, it may act as a scaffold. Inhibits KDM1A-mediated demethylation of 'Lys-4' of histone H3 in vitro, suggesting a role in demethylation regulation. [a.k.a. ENST00000528893.1, XP_016873391, ENST00000529734]

2) '9606.ENSP00000334090':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

3) '9606.ENSP00000301019':

CDT1 - DNA replication factor Cdt1; Required for both DNA replication and mitosis. DNA replication licensing factor, required for pre- replication complex assembly. Cooperates with CDC6 and the origin recognition complex (ORC) during G1 phase of the cell cycle to promote the loading of the mini-chromosome maintenance (MCM) complex onto DNA to generate pre-replication complexes (pre-RC). Required also for mitosis by promoting stable kinetochore-microtubule attachments. Potential oncogene (By similarity). Belongs to the Cdt1 family. [a.k.a. R-HSA-69278, AF070552, R-HSA-69002]

4) '9606.ENSP00000313408':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

5) '9606.ENSP00000316338':

BAIAP2 - Brain-specific angiogenesis inhibitor 1-associated protein 2; Adapter protein that links membrane-bound small G-proteins to cytoplasmic effector proteins. Necessary for CDC42-mediated reorganization of the actin cytoskeleton and for RAC1-mediated membrane ruffling. Involved in the regulation of the actin cytoskeleton by WASF family members and the Arp2/3 complex. Plays a role in neurite growth. Acts syngeristically with ENAH to promote filipodia formation. Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection. Participates in actin bundling whe [...] [a.k.a. ENSP00000459730, I3L3C6, ENST00000576995.1]

6) '9606.ENSP00000219343':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

7) '9606.ENSP00000377867':

STK26 - Serine/threonine-protein kinase 26; Mediator of cell growth. Modulates apoptosis. In association with STK24 negatively regulates Golgi reorientation in polarized cell migration upon RHO activation. [a.k.a. ENST00000361307, ENST00000312420, R-HSA-109581]

8) '9606.ENSP00000442563':

POLG2 - DNA polymerase subunit gamma-2, mitochondrial; Mitochondrial polymerase processivity subunit. Stimulates the polymerase and exonuclease activities, and increases the processivity of the enzyme. Binds to ss-DNA. [a.k.a. polymerase (DNA) gamma 2, accessory subunit, ADP91704.1, BC009194]

9) '9606.ENSP00000234420':

MSH6 - DNA mismatch repair protein Msh6; Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS alpha, which binds to DNA mismatches thereby initiating DNA repair. When bound, MutS alpha bends the DNA helix and shields approximately 20 base pairs, and recognizes single base mismatches and dinucleotide insertion-deletion loops (IDL) in the DNA. After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, a [...] [a.k.a. HPA028446, XP_024308589.1, XP_024308590]

10) '9606.ENSP00000470734':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

11) '9606.ENSP00000246337':

UROD - Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. [a.k.a. ENST00000478467, ENST00000652287, ENST00000466193]

12) '9606.ENSP00000381793':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

13) '9606.ENSP00000302564':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

14) '9606.ENSP00000313681':

SPHK1 - Sphingosine kinase 1; Catalyzes the phosphorylation of sphingosine to form sphingosine 1-phosphate (SPP), a lipid mediator with both intra- and extracellular functions. Also acts on D-erythro-sphingosine and to a lesser extent sphinganine, but not other lipids, such as D,L-threo- dihydrosphingosine, N,N-dimethylsphingosine, diacylglycerol, ceramide, or phosphatidylinositol. In contrast to proapoptotic SPHK2, has a negative effect on intracellular ceramide levels, enhances cell growth and inhibits apoptosis. Involved in the regulation of inflammatory response and neuroinflammation. Via [...] [a.k.a. AF266756, ENSP00000465726, uc002jrf.1]

15) '9606.ENSP00000436337':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

16) '9606.ENSP00000219782':

MAZ - Myc-associated zinc finger protein; May function as a transcription factor with dual roles in transcription initiation and termination. Binds to two sites, ME1a1 and ME1a2, within the MYC promoter having greater affinity for the former. Also binds to multiple G/C-rich sites within the promoter of the Sp1 family of transcription factors. Regulates inflammation-induced expression of serum amyloid A proteins. [a.k.a. HPA065930, I3L4D3, UPI0000EE81B1]

17) '9606.ENSP00000267197':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

18) '9606.ENSP00000384889':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

19) '9606.ENSP00000297508':

MICALL2 - MICAL-like protein 2; Effector of small Rab GTPases which is involved in junctional complexes assembly through the regulation of cell adhesion molecules transport to the plasma membrane and actin cytoskeleton reorganization. Regulates the endocytic recycling of occludins, claudins and E-cadherin to the plasma membrane and may thereby regulate the establishment of tight junctions and adherens junctions. In parallel, may regulate actin cytoskeleton reorganization directly through interaction with F-actin or indirectly through actinins and filamins. Most probably involved in the processes [...] [a.k.a. ENST00000413446, 79778, Q8TEQ4]

20) '9606.ENSP00000393333':

TBXA2R - Thromboxane A2 receptor; Receptor for thromboxane A2 (TXA2), a potent stimulator of platelet aggregation. The activity of this receptor is mediated by a G- protein that activates a phosphatidylinositol-calcium second messenger system. In the kidney, the binding of TXA2 to glomerular TP receptors causes intense vasoconstriction. Activates phospholipase C. Isoform 1 activates adenylyl cyclase. Isoform 2 inhibits adenylyl cyclase. [a.k.a. R-HSA-388396, AAH74750.1, CCDS54198.1]

101 query items

showing page 1 of 6 • first • previous • next • last

<- Back ⤓ Mapping Continue ->

© STRING Consortium 2023

Credits

Access

Info

About