searching ... STRING: functional protein association networks

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The following proteins in Homo sapiens appear to match your input.
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101 query items

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1) '9606.ENSP00000432561':

HTN3 - His3-(20-30)-peptide; Histatins are salivary proteins that are considered to be major precursors of the protective proteinaceous structure on tooth surfaces (enamel pellicle). In addition, histatins exhibit antibacterial and antifungal activities. His3-(20-43)-peptide (histatin-5) is especially effective against C.albicans and C.neoformans, and inhibits Lys-gingipain and Arg-gingipain (rgpB) from P.gingivalis. In addition, His3-(20-43)-peptide is a potent inhibitor of metalloproteinases MMP2 and MMP9. [a.k.a. ENST00000528003.5, L05513, Histatin-3 13/24]

2) '9606.ENSP00000264433':

FNIP2 - Folliculin-interacting protein 2; Acts as a co-chaperone of HSP90AA1. Inhibits the ATPase activity of HSP90AA1 leading to reduction in its chaperone activity. Facilitates the binding of client protein FLCN to HSP90AA1. May play a role in the signal transduction pathway of apoptosis induced by O6-methylguanine-mispaired lesions (By similarity). May be involved in energy and/or nutrient sensing through the AMPK and mTOR signaling pathways. May regulate phosphorylation of RPS6KB1. [a.k.a. KIAA1450, NP_001332972.1, ENST00000505445.1]

3) '9606.ENSP00000391989':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

4) '9606.ENSP00000391742':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

5) '9606.ENSP00000261514':

CLCN3 - H(+)/Cl(-) exchange transporter 3; Mediates the exchange of chloride ions against protons. Functions as antiporter and contributes to the acidification of the endosome and synaptic vesicle lumen, and may thereby affect vesicle trafficking and exocytosis. May play an important role in neuronal cell function through regulation of membrane excitability by protein kinase C. It could help neuronal cells to establish short-term memory. [a.k.a. ENST00000347613.8, Chloride voltage-gated channel 3, XP_005262783.1]

6) '9606.ENSP00000278836':

MYRF - Myelin regulatory factor, C-terminal; [Myelin regulatory factor]: Constitutes a precursor of the transcription factor. Mediates the autocatalytic cleavage that releases the Myelin regulatory factor, N-terminal component that specifically activates transcription of central nervous system (CNS) myelin genes. [Myelin regulatory factor, N-terminal]: Transcription factor that specifically activates expression of myelin genes such as MBP, MOG, MAG, DUSP15 and PLP1 during oligodendrocyte (OL) maturation, thereby playing a central role in oligodendrocyte maturation and CNS myelination. Specifi [...] [a.k.a. ENSP00000374254, MRF, XP_005274282]

7) '9606.ENSP00000356182':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

8) '9606.ENSP00000368813':

KLHL34 - Kelch-like protein 34; Kelch like family member 34. [a.k.a. BC109031, ENSP00000368813, Kelch-like protein 34]

9) '9606.ENSP00000392762':

DCT - L-dopachrome tautomerase; Catalyzes the conversion of L-dopachrome into 5,6- dihydroxyindole-2-carboxylic acid (DHICA). Involved in regulating eumelanin and phaeomelanin levels. Belongs to the tyrosinase family. [a.k.a. NP_001309114.1, XM_017020401.2, TRP2]

10) '9606.ENSP00000276654':

LRP12 - Low-density lipoprotein receptor-related protein 12; Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. May act as a tumor suppressor; Belongs to the LDLR family. [a.k.a. R-HSA-388396, R-HSA-196854, R-HSA-975634]

11) '9606.ENSP00000227251':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

12) '9606.ENSP00000086933':

GSC2 - Homeobox protein goosecoid-2; May have a role in development. May regulate its own transcription. May bind the bicoid consensus sequence TAATCC; Belongs to the paired homeobox family. Bicoid subfamily. [a.k.a. 2928, HGNC:4613, AAC39544.1]

13) '9606.ENSP00000340677':

WNT8B - Protein Wnt-8b; Ligand for members of the frizzled family of seven transmembrane receptors. May play an important role in the development and differentiation of certain forebrain structures, notably the hippocampus. [a.k.a. Q93098, R-HSA-162582, R-HSA-373080]

14) '9606.ENSP00000432016':

H7C0V5_HUMAN - ANKHD1-EIF4EBP3 readthrough. [a.k.a. ANKHD1-EIF4EBP3, UPI0000E5AC8E, MASK-BP3]

15) '9606.ENSP00000227155':

CD82 - CD82 antigen; Associates with CD4 or CD8 and delivers costimulatory signals for the TCR/CD3 pathway; Belongs to the tetraspanin (TM4SF) family. [a.k.a. ENST00000529277, ENSP00000339686, AAB23825.1]

16) '9606.ENSP00000414906':

DCTN4 - Dynactin subunit 4; Could have a dual role in dynein targeting and in ACTR1A/Arp1 subunit of dynactin pointed-end capping. Could be involved in ACTR1A pointed-end binding and in additional roles in linking dynein and dynactin to the cortical cytoskeleton. [a.k.a. DCTN4_HUMAN, XP_011535948.1, CCDS4310.1]

17) '9606.ENSP00000295824':

EFHB - EF-hand domain-containing family member B; Cytosolic sensor for calcium, modulates the interaction of STIM1 and ORAI1 upon store depletion, the activation of store-operated Ca(2+) entry (SOCE) and NFAT translocation from cytosol to nucleus. [a.k.a. XM_005264889, EFHB-206, AK122616]

18) '9606.ENSP00000328397':

VMO1 - Vitelline membrane outer layer 1 homolog; Belongs to the VMO1 family. [a.k.a. VMO1-203, Q7Z5L0, AAQ89457.1]

19) '9606.ENSP00000424474':

SAMD14 - Sterile alpha motif domain containing 14. [a.k.a. XM_011524490, SAMD14-209, CCDS11560.1]

20) '9606.ENSP00000265085':

CPEB4 - Cytoplasmic polyadenylation element-binding protein 4; Sequence-specific RNA-binding protein that binds to the cytoplasmic polyadenylation element (CPE), an uridine-rich sequence element (consensus sequence 5'-UUUUUAU-3') within the mRNA 3'-UTR. RNA binding results in a clear conformational change analogous to the Venus fly trap mechanism. Regulates activation of unfolded protein response (UPR) in the process of adaptation to ER stress in liver, by maintaining translation of CPE- regulated mRNAs in conditions in which global protein synthesis is inhibited (By similarity). Required for [...] [a.k.a. ENSP00000334533, CCDS4390.1, ENST00000334035.9]

101 query items

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