searching ... STRING: functional protein association networks

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The following proteins in Homo sapiens appear to match your input.
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101 query items

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1) '9606.ENSP00000444788':

TDO2 - Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. [a.k.a. 6A4I, TDO, ENSG00000151790]

2) '9606.ENSP00000251473':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

3) '9606.ENSP00000364858':

CARD16 - Caspase recruitment domain-containing protein 16; Caspase inhibitor. Acts as a regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-interleukin-1 beta (IL1B) and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. Also induces NF-kappa-B activation during the pro-inflammatory cytokine response. Also able to inhibit CASP1-mediated neuronal cell death, TNF- alpha, hypoxia-, UV-, and staurosporine-mediated cell death but not ER stress-mediated cell death. Acts by preventing activation of cas [...] [a.k.a. caspase recruitment domain family member 16, hsa:114769, ENSG00000204397]

4) '9606.ENSP00000369654':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

5) '9606.ENSP00000441828':

HPR - Haptoglobin-related protein; Primate-specific plasma protein associated with apolipoprotein L-I (apoL-I)-containing high-density lipoprotein (HDL). This HDL particle, termed trypanosome lytic factor-1 (TLF-1), mediates human innate immune protection against many species of African trypanosomes. Binds hemoglobin with high affinity and may contribute to the clearance of cell-free hemoglobin to allow hepatic recycling of heme iron. [a.k.a. XM_024450251.1, HP, X01790]

6) '9606.ENSP00000256104':

FABP4 - Fatty acid-binding protein, adipocyte; Lipid transport protein in adipocytes. Binds both long chain fatty acids and retinoic acid. Delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus. Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. [a.k.a. P15090, NP_001433, R-HSA-556833]

7) '9606.ENSP00000284322':

ABI3BP - Target of Nesh-SH3; ABI family member 3 binding protein. [a.k.a. XM_005247300.3, XP_011510955, XP_011510959]

8) '9606.ENSP00000231009':

GZMK - Granzyme K; Belongs to the peptidase S1 family. Granzyme subfamily. [a.k.a. P49863, ENSP00000231009, ENSG00000113088]

9) '9606.ENSP00000323929':

A2M - Alpha-2-macroglobulin; Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region, a thioester bond is hydrolyzed and mediates the c [...] [a.k.a. NM_001347424.1, URS00008BF993, R-HSA-162582]

10) '9606.ENSP00000323805':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

11) '9606.ENSP00000261693':

SCARB1 - Scavenger receptor class B member 1; Receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells. Receptor for HDL, mediating selective uptake of cholesteryl ether and HDL-dependent cholesterol efflux. Also facilitates the flux of free and esterified cholesterol between the cell surface and apoB-containing lipoproteins and modified lipoproteins, although less efficiently than HDL. May be involved in the phagocytosis of apoptotic cells, via its phosphatidylserine binding activity. Belongs to the CD36 family. [a.k.a. Q52LZ5, UPI000189A7D4, NP_001076428.1]

12) '9606.ENSP00000364076':

HLA-DQA2 - HLA class II histocompatibility antigen, DQ alpha 2 chain; Binds peptides derived from antigens that access the endocytic route of antigen presenting cells (APC) and presents them on the cell surface for recognition by the CD4 T-cells. The peptide binding cleft accommodates peptides of 10-30 residues. The peptides presented by MHC class II molecules are generated mostly by degradation of proteins that access the endocytic route, where they are processed by lysosomal proteases and other hydrolases. Exogenous antigens that have been endocytosed by the APC are thus readily available for p [...] [a.k.a. HLA-DQA1, KY500360, CAM26196.1]

13) '9606.ENSP00000222543':

TFPI2 - Tissue factor pathway inhibitor 2; May play a role in the regulation of plasmin-mediated matrix remodeling. Inhibits trypsin, plasmin, factor VIIa/tissue factor and weakly factor Xa. Has no effect on thrombin. [a.k.a. AAK13254.1, UPI000E6E6E68, I02.951]

14) '9606.ENSP00000358310':

ITGA10 - Integrin alpha-10; Integrin alpha-10/beta-1 is a receptor for collagen; Belongs to the integrin alpha chain family. [a.k.a. CCDS76204.1, XP_016858113, PRO827]

15) '9606.ENSP00000232892':

AADAC - Arylacetamide deacetylase; Displays cellular triglyceride lipase activity in liver, increases the levels of intracellular fatty acids derived from the hydrolysis of newly formed triglyceride stores and plays a role in very low-density lipoprotein assembly. Displays serine esterase activity in liver. Deacetylates a variety of arylacetamide substrates, including xenobiotic compounds and procarcinogens, converting them to the primary arylamide compounds and increasing their toxicity. [a.k.a. C9K0E9, EC 3.1.1.3, AC068647]

16) '9606.ENSP00000363832':

AOX1 - Aldehyde oxidase; Oxidase with broad substrate specificity, oxidizing aromatic azaheterocycles, such as N1-methylnicotinamide, N-methylphthalazinium and phthalazine, as well as aldehydes, such as benzaldehyde, retinal, pyridoxal, and vanillin. Plays a key role in the metabolism of xenobiotics and drugs containing aromatic azaheterocyclic substituents. Participates in the bioactivation of prodrugs such as famciclovir, catalyzing the oxidation step from 6-deoxypenciclovir to penciclovir, which is a potent antiviral agent. Is probably involved in the regulation of reactive oxygen species [...] [a.k.a. AF009465, Q06278, R-HSA-196854]

17) '9606.ENSP00000264896':

SCARB2 - Lysosome membrane protein 2; Acts as a lysosomal receptor for glucosylceramidase (GBA) targeting. [a.k.a. 4TVZ, ENST00000452464, Lysosome membrane protein 2]

18) '9606.ENSP00000326407':

CLEC1A - C-type lectin domain family 1 member A. [a.k.a. ENST00000420265.2, CCDS8612.1, CLEC1A-201]

19) '9606.ENSP00000309509':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

20) '9606.ENSP00000333994':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

101 query items

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