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D09_orf451 D09_orf451 NadD NadD MPN_254 MPN_254 deoD deoD outB outB hisS hisS aspS aspS glyA glyA tdk tdk nadK nadK prs prs
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query proteins and first shell of interactors
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second shell of interactors
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filled nodes:
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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D09_orf451Nicotinate phosphoribosyl transferase-like protein; MPN047(new), 107(Himmelreich et al., 1996); Belongs to the NAPRTase family. (451 aa)    
Predicted Functional Partners:
NadD
Hypothetical protein; MPN336(new), 501(Himmelreich et al., 1996); bidomain: nucleotidyl transferase and conserved hypothetical second domain, probably phosphopantetheine adenylyltransferase activity.
  
 
 0.984
MPN_254
Conserved hypothetical protein; MPN254(new); Belongs to the CinA family.
  
 
 0.924
deoD
Purine-nucleoside phosphorylase; MPN062(new), 092(Himmelreich et al., 1996).
   
 
 0.905
outB
Probable NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
  
  
 0.825
hisS
histidyl-tRNA synthetase; MPN045(new), 109(Himmelreich et al., 1996).
     
 0.824
aspS
aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
       0.774
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.607
tdk
Thymidine kinase; MPN044(new), 110(Himmelreich et al., 1996).
       0.566
nadK
Conserved hypothetical protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
  
  
 0.491
prs
Phosphoribosylpyrophosphate synthetase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
  
  
 0.481
Your Current Organism:
Mycoplasma pneumoniae M129
NCBI taxonomy Id: 272634
Other names: M. pneumoniae M129, Mycoplasma pneumoniae ATCC 29342, Mycoplasma pneumoniae str. M129, Mycoplasma pneumoniae strain M129
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