node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
D09_orf451 | MPN_254 | MPN_047 | MPN_254 | Nicotinate phosphoribosyl transferase-like protein; MPN047(new), 107(Himmelreich et al., 1996); Belongs to the NAPRTase family. | Conserved hypothetical protein; MPN254(new); Belongs to the CinA family. | 0.924 |
D09_orf451 | NadD | MPN_047 | MPN_336 | Nicotinate phosphoribosyl transferase-like protein; MPN047(new), 107(Himmelreich et al., 1996); Belongs to the NAPRTase family. | Hypothetical protein; MPN336(new), 501(Himmelreich et al., 1996); bidomain: nucleotidyl transferase and conserved hypothetical second domain, probably phosphopantetheine adenylyltransferase activity. | 0.984 |
D09_orf451 | aspS | MPN_047 | MPN_046 | Nicotinate phosphoribosyl transferase-like protein; MPN047(new), 107(Himmelreich et al., 1996); Belongs to the NAPRTase family. | aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. | 0.774 |
D09_orf451 | deoD | MPN_047 | MPN_062 | Nicotinate phosphoribosyl transferase-like protein; MPN047(new), 107(Himmelreich et al., 1996); Belongs to the NAPRTase family. | Purine-nucleoside phosphorylase; MPN062(new), 092(Himmelreich et al., 1996). | 0.905 |
D09_orf451 | glyA | MPN_047 | MPN_576 | Nicotinate phosphoribosyl transferase-like protein; MPN047(new), 107(Himmelreich et al., 1996); Belongs to the NAPRTase family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.607 |
D09_orf451 | hisS | MPN_047 | MPN_045 | Nicotinate phosphoribosyl transferase-like protein; MPN047(new), 107(Himmelreich et al., 1996); Belongs to the NAPRTase family. | histidyl-tRNA synthetase; MPN045(new), 109(Himmelreich et al., 1996). | 0.824 |
D09_orf451 | nadK | MPN_047 | MPN_267 | Nicotinate phosphoribosyl transferase-like protein; MPN047(new), 107(Himmelreich et al., 1996); Belongs to the NAPRTase family. | Conserved hypothetical protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.491 |
D09_orf451 | outB | MPN_047 | MPN_562 | Nicotinate phosphoribosyl transferase-like protein; MPN047(new), 107(Himmelreich et al., 1996); Belongs to the NAPRTase family. | Probable NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.825 |
D09_orf451 | prs | MPN_047 | MPN_073 | Nicotinate phosphoribosyl transferase-like protein; MPN047(new), 107(Himmelreich et al., 1996); Belongs to the NAPRTase family. | Phosphoribosylpyrophosphate synthetase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.481 |
D09_orf451 | tdk | MPN_047 | MPN_044 | Nicotinate phosphoribosyl transferase-like protein; MPN047(new), 107(Himmelreich et al., 1996); Belongs to the NAPRTase family. | Thymidine kinase; MPN044(new), 110(Himmelreich et al., 1996). | 0.566 |
MPN_254 | D09_orf451 | MPN_254 | MPN_047 | Conserved hypothetical protein; MPN254(new); Belongs to the CinA family. | Nicotinate phosphoribosyl transferase-like protein; MPN047(new), 107(Himmelreich et al., 1996); Belongs to the NAPRTase family. | 0.924 |
MPN_254 | NadD | MPN_254 | MPN_336 | Conserved hypothetical protein; MPN254(new); Belongs to the CinA family. | Hypothetical protein; MPN336(new), 501(Himmelreich et al., 1996); bidomain: nucleotidyl transferase and conserved hypothetical second domain, probably phosphopantetheine adenylyltransferase activity. | 0.964 |
MPN_254 | outB | MPN_254 | MPN_562 | Conserved hypothetical protein; MPN254(new); Belongs to the CinA family. | Probable NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.472 |
NadD | D09_orf451 | MPN_336 | MPN_047 | Hypothetical protein; MPN336(new), 501(Himmelreich et al., 1996); bidomain: nucleotidyl transferase and conserved hypothetical second domain, probably phosphopantetheine adenylyltransferase activity. | Nicotinate phosphoribosyl transferase-like protein; MPN047(new), 107(Himmelreich et al., 1996); Belongs to the NAPRTase family. | 0.984 |
NadD | MPN_254 | MPN_336 | MPN_254 | Hypothetical protein; MPN336(new), 501(Himmelreich et al., 1996); bidomain: nucleotidyl transferase and conserved hypothetical second domain, probably phosphopantetheine adenylyltransferase activity. | Conserved hypothetical protein; MPN254(new); Belongs to the CinA family. | 0.964 |
NadD | aspS | MPN_336 | MPN_046 | Hypothetical protein; MPN336(new), 501(Himmelreich et al., 1996); bidomain: nucleotidyl transferase and conserved hypothetical second domain, probably phosphopantetheine adenylyltransferase activity. | aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. | 0.462 |
NadD | glyA | MPN_336 | MPN_576 | Hypothetical protein; MPN336(new), 501(Himmelreich et al., 1996); bidomain: nucleotidyl transferase and conserved hypothetical second domain, probably phosphopantetheine adenylyltransferase activity. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.727 |
NadD | hisS | MPN_336 | MPN_045 | Hypothetical protein; MPN336(new), 501(Himmelreich et al., 1996); bidomain: nucleotidyl transferase and conserved hypothetical second domain, probably phosphopantetheine adenylyltransferase activity. | histidyl-tRNA synthetase; MPN045(new), 109(Himmelreich et al., 1996). | 0.478 |
NadD | nadK | MPN_336 | MPN_267 | Hypothetical protein; MPN336(new), 501(Himmelreich et al., 1996); bidomain: nucleotidyl transferase and conserved hypothetical second domain, probably phosphopantetheine adenylyltransferase activity. | Conserved hypothetical protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.958 |
NadD | outB | MPN_336 | MPN_562 | Hypothetical protein; MPN336(new), 501(Himmelreich et al., 1996); bidomain: nucleotidyl transferase and conserved hypothetical second domain, probably phosphopantetheine adenylyltransferase activity. | Probable NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.979 |