node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
D09_orf485 | gcp | MPN_058 | MPN_059 | Conserved hypothetical protein; MPN058(new), 096(Himmelreich et al., 1996). | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.847 |
D09_orf485 | metX | MPN_058 | MPN_060 | Conserved hypothetical protein; MPN058(new), 096(Himmelreich et al., 1996). | S-adenosylmethionine synthetase 2; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.845 |
D09_orf485 | pheT | MPN_058 | MPN_106 | Conserved hypothetical protein; MPN058(new), 096(Himmelreich et al., 1996). | phenylalanyl-tRNA synthetase beta chain; MPN106(new), 049(Himmelreich et al., 1996); Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.448 |
D09_orf485 | potA | MPN_058 | MPN_055 | Conserved hypothetical protein; MPN058(new), 096(Himmelreich et al., 1996). | Spermidine/putrescine transport ATP-binding prot; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family. | 0.992 |
D09_orf485 | potB | MPN_058 | MPN_056 | Conserved hypothetical protein; MPN058(new), 096(Himmelreich et al., 1996). | Spermidine/putrescine transport system permease; Required for the activity of the bacterial transport system of putrescine and spermidine; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. | 0.991 |
D09_orf485 | potI | MPN_058 | MPN_057 | Conserved hypothetical protein; MPN058(new), 096(Himmelreich et al., 1996). | Spermidine/putrescine transport system permease; Required for the activity of the bacterial transport system of putrescine and spermidine; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. | 0.993 |
H91_orf453 | gcp | MPN_362 | MPN_059 | Hemk family protein; MPN362(new), 475(Himmelreich et al., 1996); similar to methyltransferase (S-adenosyl-methionine dependent). | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.714 |
H91_orf453 | glyA | MPN_362 | MPN_576 | Hemk family protein; MPN362(new), 475(Himmelreich et al., 1996); similar to methyltransferase (S-adenosyl-methionine dependent). | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.686 |
H91_orf453 | metX | MPN_362 | MPN_060 | Hemk family protein; MPN362(new), 475(Himmelreich et al., 1996); similar to methyltransferase (S-adenosyl-methionine dependent). | S-adenosylmethionine synthetase 2; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.696 |
H91_orf453 | pheT | MPN_362 | MPN_106 | Hemk family protein; MPN362(new), 475(Himmelreich et al., 1996); similar to methyltransferase (S-adenosyl-methionine dependent). | phenylalanyl-tRNA synthetase beta chain; MPN106(new), 049(Himmelreich et al., 1996); Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.452 |
H91_orf453 | potA | MPN_362 | MPN_055 | Hemk family protein; MPN362(new), 475(Himmelreich et al., 1996); similar to methyltransferase (S-adenosyl-methionine dependent). | Spermidine/putrescine transport ATP-binding prot; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family. | 0.651 |
H91_orf453 | yzaC | MPN_362 | MPN_461 | Hemk family protein; MPN362(new), 475(Himmelreich et al., 1996); similar to methyltransferase (S-adenosyl-methionine dependent). | KtrA, K+ Na+ uptake; MPN461(new), 379(Himmelreich et al., 1996). | 0.577 |
gcp | D09_orf485 | MPN_059 | MPN_058 | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | Conserved hypothetical protein; MPN058(new), 096(Himmelreich et al., 1996). | 0.847 |
gcp | H91_orf453 | MPN_059 | MPN_362 | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | Hemk family protein; MPN362(new), 475(Himmelreich et al., 1996); similar to methyltransferase (S-adenosyl-methionine dependent). | 0.714 |
gcp | metX | MPN_059 | MPN_060 | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | S-adenosylmethionine synthetase 2; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.897 |
gcp | mtd1 | MPN_059 | MPN_017 | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 5,10-methylene-tetrahydrofolate dehydrogenase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.444 |
gcp | pheT | MPN_059 | MPN_106 | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | phenylalanyl-tRNA synthetase beta chain; MPN106(new), 049(Himmelreich et al., 1996); Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.707 |
gcp | potA | MPN_059 | MPN_055 | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | Spermidine/putrescine transport ATP-binding prot; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family. | 0.876 |
gcp | potB | MPN_059 | MPN_056 | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | Spermidine/putrescine transport system permease; Required for the activity of the bacterial transport system of putrescine and spermidine; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. | 0.848 |
gcp | potI | MPN_059 | MPN_057 | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | Spermidine/putrescine transport system permease; Required for the activity of the bacterial transport system of putrescine and spermidine; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. | 0.847 |