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deoD deoD deoA deoA cdd cdd deoC deoC tdk tdk apt apt upp upp hpt hpt D09_orf451 D09_orf451 cpsG cpsG thyA thyA
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query proteins and first shell of interactors
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second shell of interactors
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experimentally determined
Predicted Interactions
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gene co-occurrence
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textmining
co-expression
protein homology
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deoDPurine-nucleoside phosphorylase; MPN062(new), 092(Himmelreich et al., 1996). (238 aa)    
Predicted Functional Partners:
deoA
Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.
  
 
 0.996
cdd
Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.
  
 
 0.989
deoC
Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
  
  
 0.983
tdk
Thymidine kinase; MPN044(new), 110(Himmelreich et al., 1996).
  
 
 0.964
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
    
 0.944
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
  
 
  0.932
hpt
Hypoxanthine-guanine phosphoribosyltransferase; MPN672(new), 170(Himmelreich et al., 1996).
    
 0.908
D09_orf451
Nicotinate phosphoribosyl transferase-like protein; MPN047(new), 107(Himmelreich et al., 1996); Belongs to the NAPRTase family.
   
 
 0.905
cpsG
CpsG; MPN066(new), 088(Himmelreich et al., 1996); similar to phosphomannomutase and phosphoglucomutase; Belongs to the phosphohexose mutase family.
       0.832
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
  
  
 0.747
Your Current Organism:
Mycoplasma pneumoniae M129
NCBI taxonomy Id: 272634
Other names: M. pneumoniae M129, Mycoplasma pneumoniae ATCC 29342, Mycoplasma pneumoniae str. M129, Mycoplasma pneumoniae strain M129
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