STRINGSTRING
deoA deoA deoD deoD cdd cdd deoC deoC upp upp tdk tdk cpsG cpsG apt apt plsB plsB thyA thyA yaaF yaaF
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
deoAThymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. (421 aa)    
Predicted Functional Partners:
deoD
Purine-nucleoside phosphorylase; MPN062(new), 092(Himmelreich et al., 1996).
  
 
 0.996
cdd
Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.
  
 
 0.990
deoC
Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
  
 
 0.982
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
  
 0.978
tdk
Thymidine kinase; MPN044(new), 110(Himmelreich et al., 1996).
  
 
 0.958
cpsG
CpsG; MPN066(new), 088(Himmelreich et al., 1996); similar to phosphomannomutase and phosphoglucomutase; Belongs to the phosphohexose mutase family.
     
 0.836
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
     
 0.760
plsB
1-acyl-sn-glycerol-3-phosphate acyltransferase; Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
      0.707
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
  
  
 0.675
yaaF
Deoxyguanosine kinase/deoxyadenosine kinase; MPN386(new), 452(Himmelreich et al., 1996).
  
  
 0.664
Your Current Organism:
Mycoplasma pneumoniae M129
NCBI taxonomy Id: 272634
Other names: M. pneumoniae M129, Mycoplasma pneumoniae ATCC 29342, Mycoplasma pneumoniae str. M129, Mycoplasma pneumoniae strain M129
Server load: low (24%) [HD]