STRINGSTRING
CFU_1974 CFU_1974 ligD ligD dnaN dnaN polA polA CFU_1972 CFU_1972 CFU_2745 CFU_2745 CFU_1370 CFU_1370 polB polB holB holB CFU_3618 CFU_3618 CFU_3521 CFU_3521
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CFU_1974ATP-dependent DNA ligase. (830 aa)    
Predicted Functional Partners:
ligD
Ku domain protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family.
 
  
 0.987
dnaN
DNA polymerase III beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.933
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.924
CFU_1972
Hypothetical protein.
 
    0.837
CFU_2745
DNA topoisomerase IB (poxvirus type).
 
 
 
 0.831
CFU_1370
Hypothetical protein.
 
    0.787
polB
DNA polymerase II.
   
 0.712
holB
DNA polymerase III, delta prime subunit.
   
 0.706
CFU_3618
Putative Histidinol-phosphate phosphatase.
   
 0.674
CFU_3521
Exodeoxyribonuclease III.
  
 
 0.667
Your Current Organism:
Collimonas fungivorans
NCBI taxonomy Id: 1005048
Other names: C. fungivorans Ter331, Collimonas fungivorans Ter331, Collimonas fungivorans str. Ter331, Collimonas fungivorans strain Ter331, beta proteobacterium Ter331
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.