node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Acbd6 | Nmt1 | ENSMUSP00000049124 | ENSMUSP00000021314 | Acyl-CoA-binding domain-containing protein 6; Binds long-chain acyl-coenzyme A molecules with a strong preference for unsaturated C18:1-CoA, lower affinity for unsaturated C20:4-CoA, and very weak affinity for saturated C16:0-CoA. Does not bind fatty acids (By similarity). | Glycylpeptide N-tetradecanoyltransferase 1; Adds a myristoyl group to the N-terminal glycine residue of certain cellular and viral proteins. Required for normal embryogenesis. | 0.734 |
Bid | Nmt1 | ENSMUSP00000004560 | ENSMUSP00000021314 | BH3-interacting domain death agonist p11; Induces caspases and apoptosis. Counters the protective effect of Bcl-2. The major proteolytic product p15 BID allows the release of cytochrome c. | Glycylpeptide N-tetradecanoyltransferase 1; Adds a myristoyl group to the N-terminal glycine residue of certain cellular and viral proteins. Required for normal embryogenesis. | 0.751 |
Dcakd | Hexim2 | ENSMUSP00000021313 | ENSMUSP00000053678 | Dephospho-CoA kinase domain-containing protein; Belongs to the CoaE family. | Protein HEXIM2; Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. In cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation (By similarity); Belongs to the HEXIM family. | 0.689 |
Dcakd | Nmt1 | ENSMUSP00000021313 | ENSMUSP00000021314 | Dephospho-CoA kinase domain-containing protein; Belongs to the CoaE family. | Glycylpeptide N-tetradecanoyltransferase 1; Adds a myristoyl group to the N-terminal glycine residue of certain cellular and viral proteins. Required for normal embryogenesis. | 0.779 |
Dcakd | Rundc3a | ENSMUSP00000021313 | ENSMUSP00000006750 | Dephospho-CoA kinase domain-containing protein; Belongs to the CoaE family. | RUN domain-containing protein 3A; May act as an effector of RAP2A in neuronal cells. Belongs to the RUNDC3 family. | 0.661 |
Dcakd | Slc25a39 | ENSMUSP00000021313 | ENSMUSP00000018821 | Dephospho-CoA kinase domain-containing protein; Belongs to the CoaE family. | Solute carrier family 25 member 39; Required for normal heme biosynthesis; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.630 |
Dcakd | Tmub2 | ENSMUSP00000021313 | ENSMUSP00000116327 | Dephospho-CoA kinase domain-containing protein; Belongs to the CoaE family. | Transmembrane and ubiquitin-like domain-containing protein 2. | 0.663 |
Dcakd | Ubtf | ENSMUSP00000021313 | ENSMUSP00000133844 | Dephospho-CoA kinase domain-containing protein; Belongs to the CoaE family. | Nucleolar transcription factor 1; Recognizes the ribosomal RNA gene promoter and activates transcription mediated by RNA polymerase I through cooperative interactions with the transcription factor SL1/TIF-IB complex. It binds specifically to the upstream control element. | 0.586 |
Gnat1 | Nmt1 | ENSMUSP00000010205 | ENSMUSP00000021314 | Guanine nucleotide-binding protein G(t) subunit alpha-1; Functions as signal transducer for the rod photoreceptor RHO. Required for normal RHO-mediated light perception by the retina (By similarity). Guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs), such as the photoreceptor RHO. The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state. Activated RHO promotes GDP release and GTP binding. Signaling is mediated via downstream eff [...] | Glycylpeptide N-tetradecanoyltransferase 1; Adds a myristoyl group to the N-terminal glycine residue of certain cellular and viral proteins. Required for normal embryogenesis. | 0.756 |
Hexim2 | Dcakd | ENSMUSP00000053678 | ENSMUSP00000021313 | Protein HEXIM2; Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. In cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation (By similarity); Belongs to the HEXIM family. | Dephospho-CoA kinase domain-containing protein; Belongs to the CoaE family. | 0.689 |
Hexim2 | Nmt1 | ENSMUSP00000053678 | ENSMUSP00000021314 | Protein HEXIM2; Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. In cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation (By similarity); Belongs to the HEXIM family. | Glycylpeptide N-tetradecanoyltransferase 1; Adds a myristoyl group to the N-terminal glycine residue of certain cellular and viral proteins. Required for normal embryogenesis. | 0.638 |
Hexim2 | Rundc3a | ENSMUSP00000053678 | ENSMUSP00000006750 | Protein HEXIM2; Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. In cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation (By similarity); Belongs to the HEXIM family. | RUN domain-containing protein 3A; May act as an effector of RAP2A in neuronal cells. Belongs to the RUNDC3 family. | 0.623 |
Hexim2 | Slc25a39 | ENSMUSP00000053678 | ENSMUSP00000018821 | Protein HEXIM2; Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. In cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation (By similarity); Belongs to the HEXIM family. | Solute carrier family 25 member 39; Required for normal heme biosynthesis; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.599 |
Hexim2 | Tmub2 | ENSMUSP00000053678 | ENSMUSP00000116327 | Protein HEXIM2; Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. In cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation (By similarity); Belongs to the HEXIM family. | Transmembrane and ubiquitin-like domain-containing protein 2. | 0.628 |
Hexim2 | Ubtf | ENSMUSP00000053678 | ENSMUSP00000133844 | Protein HEXIM2; Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. In cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation (By similarity); Belongs to the HEXIM family. | Nucleolar transcription factor 1; Recognizes the ribosomal RNA gene promoter and activates transcription mediated by RNA polymerase I through cooperative interactions with the transcription factor SL1/TIF-IB complex. It binds specifically to the upstream control element. | 0.585 |
Nmt1 | Acbd6 | ENSMUSP00000021314 | ENSMUSP00000049124 | Glycylpeptide N-tetradecanoyltransferase 1; Adds a myristoyl group to the N-terminal glycine residue of certain cellular and viral proteins. Required for normal embryogenesis. | Acyl-CoA-binding domain-containing protein 6; Binds long-chain acyl-coenzyme A molecules with a strong preference for unsaturated C18:1-CoA, lower affinity for unsaturated C20:4-CoA, and very weak affinity for saturated C16:0-CoA. Does not bind fatty acids (By similarity). | 0.734 |
Nmt1 | Bid | ENSMUSP00000021314 | ENSMUSP00000004560 | Glycylpeptide N-tetradecanoyltransferase 1; Adds a myristoyl group to the N-terminal glycine residue of certain cellular and viral proteins. Required for normal embryogenesis. | BH3-interacting domain death agonist p11; Induces caspases and apoptosis. Counters the protective effect of Bcl-2. The major proteolytic product p15 BID allows the release of cytochrome c. | 0.751 |
Nmt1 | Dcakd | ENSMUSP00000021314 | ENSMUSP00000021313 | Glycylpeptide N-tetradecanoyltransferase 1; Adds a myristoyl group to the N-terminal glycine residue of certain cellular and viral proteins. Required for normal embryogenesis. | Dephospho-CoA kinase domain-containing protein; Belongs to the CoaE family. | 0.779 |
Nmt1 | Gnat1 | ENSMUSP00000021314 | ENSMUSP00000010205 | Glycylpeptide N-tetradecanoyltransferase 1; Adds a myristoyl group to the N-terminal glycine residue of certain cellular and viral proteins. Required for normal embryogenesis. | Guanine nucleotide-binding protein G(t) subunit alpha-1; Functions as signal transducer for the rod photoreceptor RHO. Required for normal RHO-mediated light perception by the retina (By similarity). Guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs), such as the photoreceptor RHO. The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state. Activated RHO promotes GDP release and GTP binding. Signaling is mediated via downstream eff [...] | 0.756 |
Nmt1 | Hexim2 | ENSMUSP00000021314 | ENSMUSP00000053678 | Glycylpeptide N-tetradecanoyltransferase 1; Adds a myristoyl group to the N-terminal glycine residue of certain cellular and viral proteins. Required for normal embryogenesis. | Protein HEXIM2; Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. In cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation (By similarity); Belongs to the HEXIM family. | 0.638 |