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Ogfod2 Ogfod2 Arl6ip4 Arl6ip4 Ctdspl2 Ctdspl2 Abcb9 Abcb9 Wdr83 Wdr83 Trmt2a Trmt2a Ogfod1 Ogfod1 Ogfod3 Ogfod3 Jmjd4 Jmjd4 Tmem218 Tmem218 Wbp1 Wbp1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
Ogfod22-oxoglutarate and iron-dependent oxygenase domain-containing protein 2; Belongs to the OGFOD2 family. (349 aa)    
Predicted Functional Partners:
Arl6ip4
ADP-ribosylation factor-like protein 6-interacting protein 4; Involved in modulating alternative pre-mRNA splicing with either 5' distal site activation or preferential use of 3' proximal site; Belongs to the ARL6IP4 family.
 
 
  
 0.702
Ctdspl2
CTD small phosphatase-like protein 2; Probable phosphatase; Belongs to the CTDSPL2 family.
      
 0.683
Abcb9
ATP-binding cassette sub-family B member 9; ATP-dependent low-affinity peptide transporter which translocates a broad spectrum of peptides from the cytosol to the lysosomal lumen. Displays a broad peptide length specificity from 6-mer up to at least 59-mer peptides with an optimum of 23-mers. Favors positively charged, aromatic or hydrophobic residues in the N- and C- terminal positions whereas negatively charged residues as well as asparagine and methionine are not favored (By similarity). Belongs to the ABC transporter superfamily. ABCB family. MHC peptide exporter (TC 3.A.1.209) sub [...]
   
  
 0.666
Wdr83
WD repeat domain-containing protein 83; Molecular scaffold protein for various multimeric protein complexes. Involved in response to hypoxia by acting as a negative regulator of HIF1A/HIF-1-alpha via its interaction with EGLN3/PHD3. May promote degradation of HIF1A. May act by recruiting signaling complexes to a specific upstream activator (By similarity). Also acts as a module in the assembly of a multicomponent scaffold for the ERK pathway, linking ERK responses to specific agonists. At low concentrations it enhances ERK activation, whereas high concentrations lead to the inhibition [...]
   
  
 0.603
Trmt2a
tRNA (uracil-5-)-methyltransferase homolog A.
   
    0.589
Ogfod1
Prolyl 3-hydroxylase OGFOD1; Prolyl 3-hydroxylase that catalyzes 3-hydroxylation of 'Pro- 62' of small ribosomal subunit uS12 (RPS23), thereby regulating protein translation termination efficiency. Involved in stress granule formation.
   
  
 0.576
Ogfod3
2-oxoglutarate and iron-dependent oxygenase domain-containing protein 3.
   
 
 0.570
Jmjd4
2-oxoglutarate and iron-dependent oxygenase JMJD4; Catalyzes the 2-oxoglutarate and iron-dependent C4-lysyl hydroxylation of ETF1 at 'Lys-63' thereby promoting the translational termination efficiency of ETF1 (By similarity). Not essential for embryonic stem cell (ESC) maintenance and the embryonic and postnatal development.
   
  
 0.562
Tmem218
Transmembrane protein 218; May be involved in ciliary biogenesis or function.
   
  
 0.556
Wbp1
WW domain-binding protein 1.
   
  
 0.555
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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