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Lcn3 Lcn3 Lcn8 Lcn8 Obp1a Obp1a Gm14744 Gm14744 Obp1b Obp1b Gm5938 Gm5938 Lmbr1l Lmbr1l Mup2 Mup2 Bpifa6 Bpifa6 C8g C8g Lcn6 Lcn6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
Lcn3Vomeronasal secretory protein 1; Transport of lipophilic molecules, possible pheromone- carrier. (187 aa)    
Predicted Functional Partners:
Lcn8
Epididymal-specific lipocalin-8; May play a role in male fertility. May act as a retinoid carrier protein within the epididymis.
   
  
 0.727
Obp1a
Odorant-binding protein 1a; Binds the chemical odorant 2-isobutyl-3-methoxypyrazine.
   
  
 0.685
Gm14744
Predicted gene 14744; Belongs to the calycin superfamily. Lipocalin family.
   
  
 0.682
Obp1b
Odorant-binding protein 1b; Binds the chemical odorant 2-isobutyl-3-methoxypyrazine.
   
  
 0.653
Gm5938
Predicted gene 5938; Belongs to the calycin superfamily. Lipocalin family.
      
 0.643
Lmbr1l
Protein LMBR1L; Plays an essential role in lymphocyte development by negatively regulating the canonical Wnt signaling pathway. In association with UBAC2 and E3 ubiquitin-protein ligase AMFR, promotes the ubiquitin-mediated degradation of CTNNB1 and Wnt receptors FZD6 and LRP6. LMBR1L stabilizes the beta-catenin destruction complex that is required for regulating CTNNB1 levels. Acts as a LCN1 receptor and can mediate its endocytosis (By similarity); Belongs to the LIMR family.
    
 
 0.640
Mup2
Major urinary protein 2; Belongs to the calycin superfamily. Lipocalin family.
   
  
 0.621
Bpifa6
BPI fold-containing family A, member 6.
   
  
 0.613
C8g
Complement component C8 gamma chain; C8 is a constituent of the membrane attack complex. C8 binds to the C5B-7 complex, forming the C5B-8 complex. C5-B8 binds C9 and acts as a catalyst in the polymerization of C9. The gamma subunit seems to be able to bind retinol (By similarity).
   
  
 0.595
Lcn6
LCN6 isoform alpha; Belongs to the calycin superfamily. Lipocalin family.
   
  
 0.570
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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