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Mrpl33 Mrpl33 Mrpl27 Mrpl27 Mrpl21 Mrpl21 Mrpl20 Mrpl20 Mrpl19 Mrpl19 Rps3 Rps3 Mrpl12 Mrpl12 Mrps9 Mrps9 Rps15 Rps15 Rpl5 Rpl5 Rpl23a Rpl23a
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mrpl3339S ribosomal protein L33, mitochondrial; Belongs to the bacterial ribosomal protein bL33 family. (65 aa)    
Predicted Functional Partners:
Mrpl27
39S ribosomal protein L27, mitochondrial; Belongs to the bacterial ribosomal protein bL27 family.
  
 
 0.999
Mrpl21
39S ribosomal protein L21, mitochondrial.
   
 
 0.999
Mrpl20
39S ribosomal protein L20, mitochondrial; Belongs to the bacterial ribosomal protein bL20 family.
  
 
 0.999
Mrpl19
39S ribosomal protein L19, mitochondrial; Belongs to the bacterial ribosomal protein bL19 family.
  
 
 0.999
Rps3
40S ribosomal protein S3; Involved in translation as a component of the 40S small ribosomal subunit (By similarity). Has endonuclease activity and plays a role in repair of damaged DNA. Cleaves phosphodiester bonds of DNAs containing altered bases with broad specificity and cleaves supercoiled DNA more efficiently than relaxed DNA (By similarity). Displays high binding affinity for 7,8-dihydro-8- oxoguanine (8-oxoG), a common DNA lesion caused by reactive oxygen species (ROS) (By similarity). Has also been shown to bind with similar affinity to intact and damaged DNA (By similarity). S [...]
  
 
 0.999
Mrpl12
39S ribosomal protein L12, mitochondrial; Belongs to the bacterial ribosomal protein bL12 family.
  
 
 0.999
Mrps9
28S ribosomal protein S9, mitochondrial; Belongs to the universal ribosomal protein uS9 family.
  
 
 0.999
Rps15
40S ribosomal protein S15; Belongs to the universal ribosomal protein uS19 family.
  
 
 0.999
Rpl5
60S ribosomal protein L5; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through [...]
  
 
 0.999
Rpl23a
60S ribosomal protein L23a; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Binds a specific region on the 26S rRNA (By similarity). May promote p53/TP53 degradation possibly through the stimulation of MDM2-mediated TP53 polyubiquitination (By similarity); Belongs to the universal ribosomal protein uL23 family.
  
 
 0.999
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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