node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AY074887 | Mamdc2 | ENSMUSP00000049861 | ENSMUSP00000045432 | Cleft palate-related protein 1. | MAM domain-containing protein 2. | 0.431 |
Fam163a | Mamdc2 | ENSMUSP00000015628 | ENSMUSP00000045432 | Protein FAM163A. | MAM domain-containing protein 2. | 0.655 |
Mamdc2 | AY074887 | ENSMUSP00000045432 | ENSMUSP00000049861 | MAM domain-containing protein 2. | Cleft palate-related protein 1. | 0.431 |
Mamdc2 | Fam163a | ENSMUSP00000045432 | ENSMUSP00000015628 | MAM domain-containing protein 2. | Protein FAM163A. | 0.655 |
Mamdc2 | Mrgprf | ENSMUSP00000045432 | ENSMUSP00000033386 | MAM domain-containing protein 2. | Mas-related G-protein coupled receptor member F; Orphan receptor. May bind to a neuropeptide and may regulate nociceptor function and/or development, including the sensation or modulation of pain; Belongs to the G-protein coupled receptor 1 family. Mas subfamily. | 0.402 |
Mamdc2 | Ncapd3 | ENSMUSP00000045432 | ENSMUSP00000072871 | MAM domain-containing protein 2. | Condensin-2 complex subunit D3; Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid axis. May promote the resolution of double-strand DNA catenanes (intertwines) between sister chromatids. Condensin-mediated compaction likely increases tension in catenated sister chromatids, providing directionality for type II topoisomerase- mediated strand exchanges toward chromatid decatenation. Specifically required for decatenation of centromeric ultrafine DNA bridges during anaphase. Early [...] | 0.560 |
Mamdc2 | Rab21 | ENSMUSP00000045432 | ENSMUSP00000020343 | MAM domain-containing protein 2. | Ras-related protein Rab-21; Regulates integrin internalization and recycling, but does not influence the traffic of endosomally translocated receptors in general. As a result, may regulate cell adhesion and migration. During the mitosis of adherent cells, controls the endosomal trafficking of integrins which is required for the successful completion of cytokinesis. Involved in neurite growth (By similarity). Following SBF2/MTMT13-mediated activation in response to starvation-induced autophagy, binds to and regulates SNARE protein VAMP8 endolysosomal transport required for SNARE-mediate [...] | 0.585 |
Mamdc2 | Tsn | ENSMUSP00000045432 | ENSMUSP00000027623 | MAM domain-containing protein 2. | Translin; DNA-binding protein that specifically recognizes consensus sequences at the breakpoint junctions in chromosomal translocations, mostly involving immunoglobulin (Ig)/T-cell receptor gene segments. Seems to recognize single-stranded DNA ends generated by staggered breaks occurring at recombination hot spots. Belongs to the translin family. | 0.449 |
Mrgprf | Mamdc2 | ENSMUSP00000033386 | ENSMUSP00000045432 | Mas-related G-protein coupled receptor member F; Orphan receptor. May bind to a neuropeptide and may regulate nociceptor function and/or development, including the sensation or modulation of pain; Belongs to the G-protein coupled receptor 1 family. Mas subfamily. | MAM domain-containing protein 2. | 0.402 |
Ncapd3 | Mamdc2 | ENSMUSP00000072871 | ENSMUSP00000045432 | Condensin-2 complex subunit D3; Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid axis. May promote the resolution of double-strand DNA catenanes (intertwines) between sister chromatids. Condensin-mediated compaction likely increases tension in catenated sister chromatids, providing directionality for type II topoisomerase- mediated strand exchanges toward chromatid decatenation. Specifically required for decatenation of centromeric ultrafine DNA bridges during anaphase. Early [...] | MAM domain-containing protein 2. | 0.560 |
Ncapd3 | Rab21 | ENSMUSP00000072871 | ENSMUSP00000020343 | Condensin-2 complex subunit D3; Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid axis. May promote the resolution of double-strand DNA catenanes (intertwines) between sister chromatids. Condensin-mediated compaction likely increases tension in catenated sister chromatids, providing directionality for type II topoisomerase- mediated strand exchanges toward chromatid decatenation. Specifically required for decatenation of centromeric ultrafine DNA bridges during anaphase. Early [...] | Ras-related protein Rab-21; Regulates integrin internalization and recycling, but does not influence the traffic of endosomally translocated receptors in general. As a result, may regulate cell adhesion and migration. During the mitosis of adherent cells, controls the endosomal trafficking of integrins which is required for the successful completion of cytokinesis. Involved in neurite growth (By similarity). Following SBF2/MTMT13-mediated activation in response to starvation-induced autophagy, binds to and regulates SNARE protein VAMP8 endolysosomal transport required for SNARE-mediate [...] | 0.596 |
Rab21 | Mamdc2 | ENSMUSP00000020343 | ENSMUSP00000045432 | Ras-related protein Rab-21; Regulates integrin internalization and recycling, but does not influence the traffic of endosomally translocated receptors in general. As a result, may regulate cell adhesion and migration. During the mitosis of adherent cells, controls the endosomal trafficking of integrins which is required for the successful completion of cytokinesis. Involved in neurite growth (By similarity). Following SBF2/MTMT13-mediated activation in response to starvation-induced autophagy, binds to and regulates SNARE protein VAMP8 endolysosomal transport required for SNARE-mediate [...] | MAM domain-containing protein 2. | 0.585 |
Rab21 | Ncapd3 | ENSMUSP00000020343 | ENSMUSP00000072871 | Ras-related protein Rab-21; Regulates integrin internalization and recycling, but does not influence the traffic of endosomally translocated receptors in general. As a result, may regulate cell adhesion and migration. During the mitosis of adherent cells, controls the endosomal trafficking of integrins which is required for the successful completion of cytokinesis. Involved in neurite growth (By similarity). Following SBF2/MTMT13-mediated activation in response to starvation-induced autophagy, binds to and regulates SNARE protein VAMP8 endolysosomal transport required for SNARE-mediate [...] | Condensin-2 complex subunit D3; Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid axis. May promote the resolution of double-strand DNA catenanes (intertwines) between sister chromatids. Condensin-mediated compaction likely increases tension in catenated sister chromatids, providing directionality for type II topoisomerase- mediated strand exchanges toward chromatid decatenation. Specifically required for decatenation of centromeric ultrafine DNA bridges during anaphase. Early [...] | 0.596 |
Tsn | Mamdc2 | ENSMUSP00000027623 | ENSMUSP00000045432 | Translin; DNA-binding protein that specifically recognizes consensus sequences at the breakpoint junctions in chromosomal translocations, mostly involving immunoglobulin (Ig)/T-cell receptor gene segments. Seems to recognize single-stranded DNA ends generated by staggered breaks occurring at recombination hot spots. Belongs to the translin family. | MAM domain-containing protein 2. | 0.449 |