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Tafa2 Tafa2 Fam155a Fam155a Ppfia2 Ppfia2 Cwf19l2 Cwf19l2 Tmem117 Tmem117 Kbtbd12 Kbtbd12 Tnk2 Tnk2 Tmem161b Tmem161b Naaladl2 Naaladl2 Tmem179 Tmem179 Erich3 Erich3
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Tafa2Chemokine-like protein TAFA-2; Has a role as neurotrophic factor involved in neuronal survival and neurobiological functions. (135 aa)    
Predicted Functional Partners:
Fam155a
Transmembrane protein FAM155A; Belongs to the FAM155 family.
   
  
 0.576
Ppfia2
Liprin-alpha-2; Alters PTPRF cellular localization and induces PTPRF clustering. May regulate the disassembly of focal adhesions. May localize receptor-like tyrosine phosphatases type 2A at specific sites on the plasma membrane, possibly regulating their interaction with the extracellular environment and their association with substrates. In neuronal cells, is a scaffolding protein in the dendritic spines which acts as immobile postsynaptic post able to recruit KIF1A-driven dense core vesicles to dendritic spines; Belongs to the liprin family. Liprin-alpha subfamily.
   
  
 0.516
Cwf19l2
CWF19-like protein 2.
      
 0.492
Tmem117
Transmembrane protein 117; Involved in endoplasmic reticulum (ER) stress-induced cell death pathway; Belongs to the TMEM117 family.
   
  
 0.486
Kbtbd12
Kelch repeat and BTB domain-containing protein 12.
      
 0.481
Tnk2
Activated CDC42 kinase 1; Non-receptor tyrosine-protein and serine/threonine-protein kinase that is implicated in cell spreading and migration, cell survival, cell growth and proliferation. Transduces extracellular signals to cytosolic and nuclear effectors. Phosphorylates AKT1, AR, MCF2, WASL and WWOX. Implicated in trafficking and clathrin-mediated endocytosis through binding to epidermal growth factor receptor (EGFR) and clathrin. Binds to both poly- and mono-ubiquitin and regulates ligand-induced degradation of EGFR, thereby contributing to the accumulation of EGFR at the limiting [...]
      
 0.476
Tmem161b
Transmembrane protein 161B.
      
 0.462
Naaladl2
N-acetylated alpha-linked acidic dipeptidase-like 2.
      
 0.451
Tmem179
Transmembrane protein 179.
   
  
 0.440
Erich3
Glutamate-rich 3.
   
  
 0.435
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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