STRINGSTRING
Wdr47 Wdr47 Camsap3 Camsap3 Tmem167b Tmem167b Fbxo33 Fbxo33 Wdr78 Wdr78 Aknad1 Aknad1 Fndc7 Fndc7 Rabggtb Rabggtb Wdr63 Wdr63 Lsmem1 Lsmem1 Stmn2 Stmn2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Wdr47WD repeat-containing protein 47. (920 aa)    
Predicted Functional Partners:
Camsap3
Calmodulin-regulated spectrin-associated protein 3; Key microtubule-organizing protein that specifically binds the minus-end of non-centrosomal microtubules and regulates their dynamics and organization. Specifically recognizes growing microtubule minus- ends and autonomously decorates and stabilizes microtubule lattice formed by microtubule minus-end polymerization. Acts on free microtubule minus-ends that are not capped by microtubule- nucleating proteins or other factors and protects microtubule minus- ends from depolymerization. In addition, it also reduces the velocity of microtub [...]
 
 
 
 0.937
Tmem167b
Protein kish-B; Involved in the early part of the secretory pathway. Belongs to the KISH family.
   
  
 0.646
Fbxo33
F-box only protein 33; Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins. Recognizes YBX1.
   
  
 0.635
Wdr78
WD repeat-containing protein 78.
   
  
 0.624
Aknad1
AKNA domain-containing 1.
      
 0.578
Fndc7
Fibronectin type III domain-containing protein 7.
      
 0.565
Rabggtb
Geranylgeranyl transferase type-2 subunit beta; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of Rab proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX, such as RAB1A, RAB3A, RAB5A and RAB7A.
      
 0.543
Wdr63
WD repeat domain 63.
      
 0.541
Lsmem1
Leucine-rich single-pass membrane protein 1.
      
 0.538
Stmn2
Stathmin-2; Regulator of microtubule stability. When phosphorylated by MAPK8, stabilizes microtubules and consequently controls neurite length in cortical neurons. In the developing brain, negatively regulates the rate of exit from multipolar stage and retards radial migration from the ventricular zone; Belongs to the stathmin family.
   
  
 0.529
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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