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Defb15 Defb15 Defb35 Defb35 Defb12 Defb12 Defb13 Defb13 Gm45826 Gm45826 Spag11a Spag11a Defb10 Defb10 Spag11b Spag11b Defb8 Defb8 Defb7 Defb7 Defb33 Defb33
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Defb15Beta-defensin 15; Has antibacterial activity. (79 aa)    
Predicted Functional Partners:
Defb35
Beta-defensin 35; Has antibacterial activity.
   
  
 0.861
Defb12
Beta-defensin 12; Has antibacterial activity.
   
  
 0.773
Defb13
Beta-defensin 13; Has antibacterial activity.
   
  
 0.773
Gm45826
Sperm-associated antigen 11; May have antimicrobial activity. May also play a role sperm maturation, storage, and protection.
      
 0.729
Spag11a
Sperm associated antigen 11A.
   
  
 0.708
Defb10
Beta-defensin 10; Has antibacterial activity.
   
  
 0.704
Spag11b
Sperm-associated antigen 11B.
   
  
 0.697
Defb8
Beta-defensin 8; A synthetic peptide displays antimicrobial activities against S.aureus, P.aeruginosa, E.coli and B.cepacia. The antimicrobial activity against S.aureus, E.coli and B.cepacia is reduced in raised concentration of NaCl, but its action against P.aeruginosa is independent of NaCl concentration.
      
 0.691
Defb7
Beta-defensin 7; Has bactericidal activity; Belongs to the beta-defensin family. LAP/TAP subfamily.
      
 0.671
Defb33
Beta-defensin 33; Has antibacterial activity; Belongs to the beta-defensin family.
   
  
 0.624
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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