Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Ahcyl1 | Car8 | ENSMUSP00000029490 | ENSMUSP00000063511 | S-adenosylhomocysteine hydrolase-like protein 1; Multifaceted cellular regulator which coordinates several essential cellular functions including regulation of epithelial HCO3(-) and fluid secretion, mRNA processing and DNA replication. Regulates ITPR1 sensitivity to inositol 1,4,5-trisphosphate competing for the common binding site and acting as endogenous 'pseudoligand' whose inhibitory activity can be modulated by its phosphorylation status. In the pancreatic and salivary ducts, at resting state, attenuates inositol 1,4,5-trisphosphate-induced calcium release by interacting with ITP [...] | Carbonic anhydrase-related protein; Does not have a carbonic anhydrase catalytic activity; Belongs to the alpha-carbonic anhydrase family. | 0.567 |
| Ahcyl1 | Itpr1 | ENSMUSP00000029490 | ENSMUSP00000032192 | S-adenosylhomocysteine hydrolase-like protein 1; Multifaceted cellular regulator which coordinates several essential cellular functions including regulation of epithelial HCO3(-) and fluid secretion, mRNA processing and DNA replication. Regulates ITPR1 sensitivity to inositol 1,4,5-trisphosphate competing for the common binding site and acting as endogenous 'pseudoligand' whose inhibitory activity can be modulated by its phosphorylation status. In the pancreatic and salivary ducts, at resting state, attenuates inositol 1,4,5-trisphosphate-induced calcium release by interacting with ITP [...] | Inositol 1,4,5-trisphosphate receptor type 1; Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5- trisphosphate. Involved in the regulation of epithelial secretion of electrolytes and fluid through the interaction with AHCYL1. Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways. | 0.939 |
| Alb | Car8 | ENSMUSP00000031314 | ENSMUSP00000063511 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | Carbonic anhydrase-related protein; Does not have a carbonic anhydrase catalytic activity; Belongs to the alpha-carbonic anhydrase family. | 0.564 |
| Alb | Serpinb1b | ENSMUSP00000031314 | ENSMUSP00000016951 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | Leukocyte elastase inhibitor B; Regulates the activity of the neutrophil proteases. Forms only a stable complex with CTSG/Cathepsin G. During inflammation, limits the activity of inflammatory caspases CASP1 and CASP4 by suppressing their caspase-recruitment domain (CARD) oligomerization and enzymatic activation. Belongs to the serpin family. Ov-serpin subfamily. | 0.916 |
| Alb | Serpinb2 | ENSMUSP00000031314 | ENSMUSP00000065277 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | Plasminogen activator inhibitor 2, macrophage; Inhibits urokinase-type plasminogen activator. The monocyte derived PAI-2 is distinct from the endothelial cell-derived PAI-1. Not required for normal murine development or survival; Belongs to the serpin family. Ov-serpin subfamily. | 0.909 |
| Alb | Serpinb6e | ENSMUSP00000031314 | ENSMUSP00000105904 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | Serine (or cysteine) peptidase inhibitor, clade B, member 6e; Belongs to the serpin family. | 0.916 |
| Alb | Serpinb8 | ENSMUSP00000031314 | ENSMUSP00000108326 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | Serpin B8; Has an important role in epithelial desmosome-mediated cell- cell adhesion; Belongs to the serpin family. Ov-serpin subfamily. | 0.916 |
| Car8 | Ahcyl1 | ENSMUSP00000063511 | ENSMUSP00000029490 | Carbonic anhydrase-related protein; Does not have a carbonic anhydrase catalytic activity; Belongs to the alpha-carbonic anhydrase family. | S-adenosylhomocysteine hydrolase-like protein 1; Multifaceted cellular regulator which coordinates several essential cellular functions including regulation of epithelial HCO3(-) and fluid secretion, mRNA processing and DNA replication. Regulates ITPR1 sensitivity to inositol 1,4,5-trisphosphate competing for the common binding site and acting as endogenous 'pseudoligand' whose inhibitory activity can be modulated by its phosphorylation status. In the pancreatic and salivary ducts, at resting state, attenuates inositol 1,4,5-trisphosphate-induced calcium release by interacting with ITP [...] | 0.567 |
| Car8 | Alb | ENSMUSP00000063511 | ENSMUSP00000031314 | Carbonic anhydrase-related protein; Does not have a carbonic anhydrase catalytic activity; Belongs to the alpha-carbonic anhydrase family. | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | 0.564 |
| Car8 | Itpr1 | ENSMUSP00000063511 | ENSMUSP00000032192 | Carbonic anhydrase-related protein; Does not have a carbonic anhydrase catalytic activity; Belongs to the alpha-carbonic anhydrase family. | Inositol 1,4,5-trisphosphate receptor type 1; Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5- trisphosphate. Involved in the regulation of epithelial secretion of electrolytes and fluid through the interaction with AHCYL1. Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways. | 0.970 |
| Car8 | Rpf2 | ENSMUSP00000063511 | ENSMUSP00000138581 | Carbonic anhydrase-related protein; Does not have a carbonic anhydrase catalytic activity; Belongs to the alpha-carbonic anhydrase family. | Ribosome production factor 2 homolog; Involved in ribosomal large subunit assembly. May regulate the localization of the 5S RNP/5S ribonucleoprotein particle to the nucleolus; Belongs to the RPF2 family. | 0.568 |
| Car8 | Sebox | ENSMUSP00000063511 | ENSMUSP00000001130 | Carbonic anhydrase-related protein; Does not have a carbonic anhydrase catalytic activity; Belongs to the alpha-carbonic anhydrase family. | Homeobox protein SEBOX; Probable transcription factor involved in the control of specification of mesoderm and endoderm; Belongs to the paired homeobox family. | 0.556 |
| Car8 | Serpinb1b | ENSMUSP00000063511 | ENSMUSP00000016951 | Carbonic anhydrase-related protein; Does not have a carbonic anhydrase catalytic activity; Belongs to the alpha-carbonic anhydrase family. | Leukocyte elastase inhibitor B; Regulates the activity of the neutrophil proteases. Forms only a stable complex with CTSG/Cathepsin G. During inflammation, limits the activity of inflammatory caspases CASP1 and CASP4 by suppressing their caspase-recruitment domain (CARD) oligomerization and enzymatic activation. Belongs to the serpin family. Ov-serpin subfamily. | 0.531 |
| Car8 | Serpinb2 | ENSMUSP00000063511 | ENSMUSP00000065277 | Carbonic anhydrase-related protein; Does not have a carbonic anhydrase catalytic activity; Belongs to the alpha-carbonic anhydrase family. | Plasminogen activator inhibitor 2, macrophage; Inhibits urokinase-type plasminogen activator. The monocyte derived PAI-2 is distinct from the endothelial cell-derived PAI-1. Not required for normal murine development or survival; Belongs to the serpin family. Ov-serpin subfamily. | 0.546 |
| Car8 | Serpinb6e | ENSMUSP00000063511 | ENSMUSP00000105904 | Carbonic anhydrase-related protein; Does not have a carbonic anhydrase catalytic activity; Belongs to the alpha-carbonic anhydrase family. | Serine (or cysteine) peptidase inhibitor, clade B, member 6e; Belongs to the serpin family. | 0.529 |
| Car8 | Serpinb8 | ENSMUSP00000063511 | ENSMUSP00000108326 | Carbonic anhydrase-related protein; Does not have a carbonic anhydrase catalytic activity; Belongs to the alpha-carbonic anhydrase family. | Serpin B8; Has an important role in epithelial desmosome-mediated cell- cell adhesion; Belongs to the serpin family. Ov-serpin subfamily. | 0.528 |
| Car8 | Zfp236 | ENSMUSP00000063511 | ENSMUSP00000130004 | Carbonic anhydrase-related protein; Does not have a carbonic anhydrase catalytic activity; Belongs to the alpha-carbonic anhydrase family. | Zinc finger protein 236. | 0.564 |
| Itpr1 | Ahcyl1 | ENSMUSP00000032192 | ENSMUSP00000029490 | Inositol 1,4,5-trisphosphate receptor type 1; Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5- trisphosphate. Involved in the regulation of epithelial secretion of electrolytes and fluid through the interaction with AHCYL1. Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways. | S-adenosylhomocysteine hydrolase-like protein 1; Multifaceted cellular regulator which coordinates several essential cellular functions including regulation of epithelial HCO3(-) and fluid secretion, mRNA processing and DNA replication. Regulates ITPR1 sensitivity to inositol 1,4,5-trisphosphate competing for the common binding site and acting as endogenous 'pseudoligand' whose inhibitory activity can be modulated by its phosphorylation status. In the pancreatic and salivary ducts, at resting state, attenuates inositol 1,4,5-trisphosphate-induced calcium release by interacting with ITP [...] | 0.939 |
| Itpr1 | Car8 | ENSMUSP00000032192 | ENSMUSP00000063511 | Inositol 1,4,5-trisphosphate receptor type 1; Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5- trisphosphate. Involved in the regulation of epithelial secretion of electrolytes and fluid through the interaction with AHCYL1. Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways. | Carbonic anhydrase-related protein; Does not have a carbonic anhydrase catalytic activity; Belongs to the alpha-carbonic anhydrase family. | 0.970 |
| Rpf2 | Car8 | ENSMUSP00000138581 | ENSMUSP00000063511 | Ribosome production factor 2 homolog; Involved in ribosomal large subunit assembly. May regulate the localization of the 5S RNP/5S ribonucleoprotein particle to the nucleolus; Belongs to the RPF2 family. | Carbonic anhydrase-related protein; Does not have a carbonic anhydrase catalytic activity; Belongs to the alpha-carbonic anhydrase family. | 0.568 |
page 1 of 3