node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Bcl2l15 | Phtf1 | ENSMUSP00000052210 | ENSMUSP00000066607 | Bcl-2-like protein 15. | Putative homeodomain transcription factor 1; May play a role in transcription regulation. | 0.547 |
Bcl2l15 | Rsbn1 | ENSMUSP00000052210 | ENSMUSP00000069246 | Bcl-2-like protein 15. | Lysine-specific demethylase 9; Histone demethylase that specifically demethylates dimethylated 'Lys-20' of histone H4 (H4K20me2), thereby modulating chromosome architecture; Belongs to the round spermatid basic protein 1 family. | 0.410 |
Commd2 | Fem1b | ENSMUSP00000124819 | ENSMUSP00000034775 | COMM domain-containing protein 2; May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes. May down-regulate activation of NF-kappa-B. | Protein fem-1 homolog B; Component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit. Involved in apoptosis by acting as a death receptor-associated protein that mediates apoptosis. Also involved in glucose homeostasis in pancreatic islet. Functions as an adapter/mediator in replication stress-induced signaling that leads to the activation of CHEK1 (By similarity); Belongs to the fem-1 family. | 0.511 |
Commd2 | Phtf1 | ENSMUSP00000124819 | ENSMUSP00000066607 | COMM domain-containing protein 2; May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes. May down-regulate activation of NF-kappa-B. | Putative homeodomain transcription factor 1; May play a role in transcription regulation. | 0.526 |
Fbxo48 | Phtf1 | ENSMUSP00000057901 | ENSMUSP00000066607 | F-box only protein 48. | Putative homeodomain transcription factor 1; May play a role in transcription regulation. | 0.491 |
Fem1b | Commd2 | ENSMUSP00000034775 | ENSMUSP00000124819 | Protein fem-1 homolog B; Component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit. Involved in apoptosis by acting as a death receptor-associated protein that mediates apoptosis. Also involved in glucose homeostasis in pancreatic islet. Functions as an adapter/mediator in replication stress-induced signaling that leads to the activation of CHEK1 (By similarity); Belongs to the fem-1 family. | COMM domain-containing protein 2; May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes. May down-regulate activation of NF-kappa-B. | 0.511 |
Fem1b | Phtf1 | ENSMUSP00000034775 | ENSMUSP00000066607 | Protein fem-1 homolog B; Component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit. Involved in apoptosis by acting as a death receptor-associated protein that mediates apoptosis. Also involved in glucose homeostasis in pancreatic islet. Functions as an adapter/mediator in replication stress-induced signaling that leads to the activation of CHEK1 (By similarity); Belongs to the fem-1 family. | Putative homeodomain transcription factor 1; May play a role in transcription regulation. | 0.534 |
Magi3 | Phtf1 | ENSMUSP00000112934 | ENSMUSP00000066607 | Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3; Acts as a scaffolding protein at cell-cell junctions, thereby regulating various cellular and signaling processes. Cooperates with PTEN to modulate the kinase activity of AKT1. Its interaction with PTPRB and tyrosine phosphorylated proteins suggests that it may link receptor tyrosine phosphatase with its substrates at the plasma membrane. In polarized epithelial cells, involved in efficient trafficking of TGFA to the cell surface. Regulates the ability of LPAR2 to activate ERK and RhoA pathways. Regulates the [...] | Putative homeodomain transcription factor 1; May play a role in transcription regulation. | 0.695 |
Nagk | Phtf1 | ENSMUSP00000109482 | ENSMUSP00000066607 | N-acetyl-D-glucosamine kinase; Converts endogenous N-acetylglucosamine (GlcNAc), a major component of complex carbohydrates, from lysosomal degradation or nutritional sources into GlcNAc 6-phosphate. Involved in the N- glycolylneuraminic acid (Neu5Gc) degradation pathway. Also has ManNAc kinase activity. | Putative homeodomain transcription factor 1; May play a role in transcription regulation. | 0.495 |
Phtf1 | Bcl2l15 | ENSMUSP00000066607 | ENSMUSP00000052210 | Putative homeodomain transcription factor 1; May play a role in transcription regulation. | Bcl-2-like protein 15. | 0.547 |
Phtf1 | Commd2 | ENSMUSP00000066607 | ENSMUSP00000124819 | Putative homeodomain transcription factor 1; May play a role in transcription regulation. | COMM domain-containing protein 2; May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes. May down-regulate activation of NF-kappa-B. | 0.526 |
Phtf1 | Fbxo48 | ENSMUSP00000066607 | ENSMUSP00000057901 | Putative homeodomain transcription factor 1; May play a role in transcription regulation. | F-box only protein 48. | 0.491 |
Phtf1 | Fem1b | ENSMUSP00000066607 | ENSMUSP00000034775 | Putative homeodomain transcription factor 1; May play a role in transcription regulation. | Protein fem-1 homolog B; Component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit. Involved in apoptosis by acting as a death receptor-associated protein that mediates apoptosis. Also involved in glucose homeostasis in pancreatic islet. Functions as an adapter/mediator in replication stress-induced signaling that leads to the activation of CHEK1 (By similarity); Belongs to the fem-1 family. | 0.534 |
Phtf1 | Magi3 | ENSMUSP00000066607 | ENSMUSP00000112934 | Putative homeodomain transcription factor 1; May play a role in transcription regulation. | Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3; Acts as a scaffolding protein at cell-cell junctions, thereby regulating various cellular and signaling processes. Cooperates with PTEN to modulate the kinase activity of AKT1. Its interaction with PTPRB and tyrosine phosphorylated proteins suggests that it may link receptor tyrosine phosphatase with its substrates at the plasma membrane. In polarized epithelial cells, involved in efficient trafficking of TGFA to the cell surface. Regulates the ability of LPAR2 to activate ERK and RhoA pathways. Regulates the [...] | 0.695 |
Phtf1 | Nagk | ENSMUSP00000066607 | ENSMUSP00000109482 | Putative homeodomain transcription factor 1; May play a role in transcription regulation. | N-acetyl-D-glucosamine kinase; Converts endogenous N-acetylglucosamine (GlcNAc), a major component of complex carbohydrates, from lysosomal degradation or nutritional sources into GlcNAc 6-phosphate. Involved in the N- glycolylneuraminic acid (Neu5Gc) degradation pathway. Also has ManNAc kinase activity. | 0.495 |
Phtf1 | Pom121l12 | ENSMUSP00000066607 | ENSMUSP00000147960 | Putative homeodomain transcription factor 1; May play a role in transcription regulation. | POM121 membrane glycoprotein-like 12. | 0.538 |
Phtf1 | Rsbn1 | ENSMUSP00000066607 | ENSMUSP00000069246 | Putative homeodomain transcription factor 1; May play a role in transcription regulation. | Lysine-specific demethylase 9; Histone demethylase that specifically demethylates dimethylated 'Lys-20' of histone H4 (H4K20me2), thereby modulating chromosome architecture; Belongs to the round spermatid basic protein 1 family. | 0.831 |
Phtf1 | Swt1 | ENSMUSP00000066607 | ENSMUSP00000067516 | Putative homeodomain transcription factor 1; May play a role in transcription regulation. | Transcriptional protein SWT1. | 0.576 |
Phtf1 | Triml2 | ENSMUSP00000066607 | ENSMUSP00000148196 | Putative homeodomain transcription factor 1; May play a role in transcription regulation. | Tripartite motif family-like 2. | 0.538 |
Pom121l12 | Phtf1 | ENSMUSP00000147960 | ENSMUSP00000066607 | POM121 membrane glycoprotein-like 12. | Putative homeodomain transcription factor 1; May play a role in transcription regulation. | 0.538 |