Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| 4931406P16Rik | Slc35e3 | ENSMUSP00000103709 | ENSMUSP00000078050 | RIKEN cDNA 4931406P16 gene. | Solute carrier family 35 member E3; Putative transporter; Belongs to the TPT transporter family. SLC35E subfamily. | 0.474 |
| 4931406P16Rik | Zfyve21 | ENSMUSP00000103709 | ENSMUSP00000021714 | RIKEN cDNA 4931406P16 gene. | Zinc finger FYVE domain-containing protein 21; Plays a role in cell adhesion, and thereby in cell motility which requires repeated formation and disassembly of focal adhesions. Regulates microtubule-induced PTK2/FAK1 dephosphorylation, an event important for focal adhesion disassembly, as well as integrin beta- 1/ITGB1 cell surface expression (By similarity). | 0.487 |
| 4931406P16Rik | Zxdc | ENSMUSP00000103709 | ENSMUSP00000074619 | RIKEN cDNA 4931406P16 gene. | Zinc finger protein ZXDC; Cooperates with CIITA to promote transcription of MHC class I and MHC class II genes. | 0.475 |
| Armc10 | Zxdc | ENSMUSP00000072669 | ENSMUSP00000074619 | Armadillo repeat-containing protein 10; May play a role in cell survival and cell growth. May suppress the transcriptional activity of p53/TP53 (By similarity). | Zinc finger protein ZXDC; Cooperates with CIITA to promote transcription of MHC class I and MHC class II genes. | 0.433 |
| Ciita | Zxdc | ENSMUSP00000023147 | ENSMUSP00000074619 | MHC class II transactivator; Essential for transcriptional activity of the HLA class II promoter; activation is via the proximal promoter. No DNA binding of in vitro translated CIITA was detected. May act in a coactivator-like fashion through protein-protein interactions by contacting factors binding to the proximal MHC class II promoter, to elements of the transcription machinery, or both. Alternatively it may activate HLA class II transcription by modifying proteins that bind to the MHC class II promoter. Also mediates enhanced MHC class I transcription, the promoter element requirem [...] | Zinc finger protein ZXDC; Cooperates with CIITA to promote transcription of MHC class I and MHC class II genes. | 0.584 |
| Fbxl17 | Zxdc | ENSMUSP00000024761 | ENSMUSP00000074619 | F-box/LRR-repeat protein 17; Substrate-recognition component of the SCF(FBXL17) E3 ubiquitin ligase complex, a key component of a quality control pathway required to ensure functional dimerization of BTB domain-containing proteins (dimerization quality control, DQC). FBXL17 specifically recognizes and binds a conserved degron of non-consecutive residues present at the interface of BTB dimers of aberrant composition: aberrant BTB dimer are then ubiquitinated by the SCF(FBXL17) complex and degraded by the proteaseome (By similarity). The ability of the SCF(FBXL17) complex to eliminate co [...] | Zinc finger protein ZXDC; Cooperates with CIITA to promote transcription of MHC class I and MHC class II genes. | 0.481 |
| Hal | Zxdc | ENSMUSP00000123336 | ENSMUSP00000074619 | Histidine ammonia-lyase; Belongs to the PAL/histidase family. | Zinc finger protein ZXDC; Cooperates with CIITA to promote transcription of MHC class I and MHC class II genes. | 0.507 |
| Lemd2 | Zxdc | ENSMUSP00000058221 | ENSMUSP00000074619 | LEM domain-containing protein 2; Involved in nuclear structure organization. Required for maintaining the integrity of the nuclear envelope (By similarity). | Zinc finger protein ZXDC; Cooperates with CIITA to promote transcription of MHC class I and MHC class II genes. | 0.443 |
| Mrps23 | Zxdc | ENSMUSP00000024486 | ENSMUSP00000074619 | 28S ribosomal protein S23, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mS23 family. | Zinc finger protein ZXDC; Cooperates with CIITA to promote transcription of MHC class I and MHC class II genes. | 0.517 |
| Slc35e3 | 4931406P16Rik | ENSMUSP00000078050 | ENSMUSP00000103709 | Solute carrier family 35 member E3; Putative transporter; Belongs to the TPT transporter family. SLC35E subfamily. | RIKEN cDNA 4931406P16 gene. | 0.474 |
| Slc35e3 | Zfyve21 | ENSMUSP00000078050 | ENSMUSP00000021714 | Solute carrier family 35 member E3; Putative transporter; Belongs to the TPT transporter family. SLC35E subfamily. | Zinc finger FYVE domain-containing protein 21; Plays a role in cell adhesion, and thereby in cell motility which requires repeated formation and disassembly of focal adhesions. Regulates microtubule-induced PTK2/FAK1 dephosphorylation, an event important for focal adhesion disassembly, as well as integrin beta- 1/ITGB1 cell surface expression (By similarity). | 0.449 |
| Slc35e3 | Zxdc | ENSMUSP00000078050 | ENSMUSP00000074619 | Solute carrier family 35 member E3; Putative transporter; Belongs to the TPT transporter family. SLC35E subfamily. | Zinc finger protein ZXDC; Cooperates with CIITA to promote transcription of MHC class I and MHC class II genes. | 0.428 |
| Zfp746 | Zxdc | ENSMUSP00000072868 | ENSMUSP00000074619 | Zinc finger protein 746; Transcription repressor that specifically binds to the 5'- TATTTT[T/G]-3' consensus sequence on promoters and repress transcription of PGC-1-alpha (PPARGC1A), thereby playing a role in regulation of neuron death; Belongs to the krueppel C2H2-type zinc-finger protein family. | Zinc finger protein ZXDC; Cooperates with CIITA to promote transcription of MHC class I and MHC class II genes. | 0.459 |
| Zfyve21 | 4931406P16Rik | ENSMUSP00000021714 | ENSMUSP00000103709 | Zinc finger FYVE domain-containing protein 21; Plays a role in cell adhesion, and thereby in cell motility which requires repeated formation and disassembly of focal adhesions. Regulates microtubule-induced PTK2/FAK1 dephosphorylation, an event important for focal adhesion disassembly, as well as integrin beta- 1/ITGB1 cell surface expression (By similarity). | RIKEN cDNA 4931406P16 gene. | 0.487 |
| Zfyve21 | Slc35e3 | ENSMUSP00000021714 | ENSMUSP00000078050 | Zinc finger FYVE domain-containing protein 21; Plays a role in cell adhesion, and thereby in cell motility which requires repeated formation and disassembly of focal adhesions. Regulates microtubule-induced PTK2/FAK1 dephosphorylation, an event important for focal adhesion disassembly, as well as integrin beta- 1/ITGB1 cell surface expression (By similarity). | Solute carrier family 35 member E3; Putative transporter; Belongs to the TPT transporter family. SLC35E subfamily. | 0.449 |
| Zfyve21 | Zxdc | ENSMUSP00000021714 | ENSMUSP00000074619 | Zinc finger FYVE domain-containing protein 21; Plays a role in cell adhesion, and thereby in cell motility which requires repeated formation and disassembly of focal adhesions. Regulates microtubule-induced PTK2/FAK1 dephosphorylation, an event important for focal adhesion disassembly, as well as integrin beta- 1/ITGB1 cell surface expression (By similarity). | Zinc finger protein ZXDC; Cooperates with CIITA to promote transcription of MHC class I and MHC class II genes. | 0.428 |
| Zxdc | 4931406P16Rik | ENSMUSP00000074619 | ENSMUSP00000103709 | Zinc finger protein ZXDC; Cooperates with CIITA to promote transcription of MHC class I and MHC class II genes. | RIKEN cDNA 4931406P16 gene. | 0.475 |
| Zxdc | Armc10 | ENSMUSP00000074619 | ENSMUSP00000072669 | Zinc finger protein ZXDC; Cooperates with CIITA to promote transcription of MHC class I and MHC class II genes. | Armadillo repeat-containing protein 10; May play a role in cell survival and cell growth. May suppress the transcriptional activity of p53/TP53 (By similarity). | 0.433 |
| Zxdc | Ciita | ENSMUSP00000074619 | ENSMUSP00000023147 | Zinc finger protein ZXDC; Cooperates with CIITA to promote transcription of MHC class I and MHC class II genes. | MHC class II transactivator; Essential for transcriptional activity of the HLA class II promoter; activation is via the proximal promoter. No DNA binding of in vitro translated CIITA was detected. May act in a coactivator-like fashion through protein-protein interactions by contacting factors binding to the proximal MHC class II promoter, to elements of the transcription machinery, or both. Alternatively it may activate HLA class II transcription by modifying proteins that bind to the MHC class II promoter. Also mediates enhanced MHC class I transcription, the promoter element requirem [...] | 0.584 |
| Zxdc | Fbxl17 | ENSMUSP00000074619 | ENSMUSP00000024761 | Zinc finger protein ZXDC; Cooperates with CIITA to promote transcription of MHC class I and MHC class II genes. | F-box/LRR-repeat protein 17; Substrate-recognition component of the SCF(FBXL17) E3 ubiquitin ligase complex, a key component of a quality control pathway required to ensure functional dimerization of BTB domain-containing proteins (dimerization quality control, DQC). FBXL17 specifically recognizes and binds a conserved degron of non-consecutive residues present at the interface of BTB dimers of aberrant composition: aberrant BTB dimer are then ubiquitinated by the SCF(FBXL17) complex and degraded by the proteaseome (By similarity). The ability of the SCF(FBXL17) complex to eliminate co [...] | 0.481 |
page 1 of 2