node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Cog8 | Stx16 | ENSMUSP00000093173 | ENSMUSP00000085218 | Conserved oligomeric Golgi complex subunit 8; Required for normal Golgi function. | Syntaxin-16; SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network; Belongs to the syntaxin family. | 0.958 |
Cog8 | Stx6 | ENSMUSP00000093173 | ENSMUSP00000027743 | Conserved oligomeric Golgi complex subunit 8; Required for normal Golgi function. | Syntaxin-6; Involved in intracellular vesicle trafficking; Belongs to the syntaxin family. | 0.873 |
Cog8 | Vamp4 | ENSMUSP00000093173 | ENSMUSP00000121977 | Conserved oligomeric Golgi complex subunit 8; Required for normal Golgi function. | Vesicle-associated membrane protein 4; Involved in the pathway that functions to remove an inhibitor (probably synaptotagmin-4) of calcium-triggered exocytosis during the maturation of secretory granules. May be a marker for this sorting pathway that is critical for remodeling the secretory response of granule (By similarity); Belongs to the synaptobrevin family. | 0.769 |
Cog8 | Vps45 | ENSMUSP00000093173 | ENSMUSP00000015891 | Conserved oligomeric Golgi complex subunit 8; Required for normal Golgi function. | Vacuolar protein sorting-associated protein 45; May play a role in vesicle-mediated protein trafficking from the Golgi stack through the trans-Golgi network. | 0.797 |
Cog8 | Vps54 | ENSMUSP00000093173 | ENSMUSP00000006221 | Conserved oligomeric Golgi complex subunit 8; Required for normal Golgi function. | Vacuolar protein sorting-associated protein 54; Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD. Within the GARP complex, required to tether the complex to the TGN. Not involved in endocytic recycling. | 0.878 |
Cog8 | Vti1a | ENSMUSP00000093173 | ENSMUSP00000093644 | Conserved oligomeric Golgi complex subunit 8; Required for normal Golgi function. | Vesicle transport through interaction with t-SNAREs homolog 1A; V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. Involved in vesicular transport from the late endosomes to the trans-Golgi network. Along with VAMP7, involved in an non-conventional RAB1-dependent traffic route to the cell surface used by KCNIP1 and KCND2. May be concerned with increased secretion of cytokines associated with ce [...] | 0.876 |
Cog8 | Vti1b | ENSMUSP00000093173 | ENSMUSP00000057462 | Conserved oligomeric Golgi complex subunit 8; Required for normal Golgi function. | Vesicle transport through interaction with t-SNAREs homolog 1B; V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. | 0.480 |
Cog8 | Ykt6 | ENSMUSP00000093173 | ENSMUSP00000002818 | Conserved oligomeric Golgi complex subunit 8; Required for normal Golgi function. | Synaptobrevin homolog YKT6; Vesicular soluble NSF attachment protein receptor (v-SNARE) mediating vesicle docking and fusion to a specific acceptor cellular compartment. Functions in endoplasmic reticulum to Golgi transport; as part of a SNARE complex composed of GOSR1, GOSR2 and STX5. Functions in early/recycling endosome to TGN transport; as part of a SNARE complex composed of BET1L, GOSR1 and STX5. Has a S-palmitoyl transferase activity; Belongs to the synaptobrevin family. | 0.871 |
Stx16 | Cog8 | ENSMUSP00000085218 | ENSMUSP00000093173 | Syntaxin-16; SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network; Belongs to the syntaxin family. | Conserved oligomeric Golgi complex subunit 8; Required for normal Golgi function. | 0.958 |
Stx16 | Stx6 | ENSMUSP00000085218 | ENSMUSP00000027743 | Syntaxin-16; SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network; Belongs to the syntaxin family. | Syntaxin-6; Involved in intracellular vesicle trafficking; Belongs to the syntaxin family. | 0.999 |
Stx16 | Stx8 | ENSMUSP00000085218 | ENSMUSP00000021285 | Syntaxin-16; SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network; Belongs to the syntaxin family. | Syntaxin-8; Vesicle trafficking protein that functions in the early secretory pathway, possibly by mediating retrograde transport from cis- Golgi membranes to the ER; Belongs to the syntaxin family. | 0.989 |
Stx16 | Vamp3 | ENSMUSP00000085218 | ENSMUSP00000030797 | Syntaxin-16; SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network; Belongs to the syntaxin family. | Vesicle-associated membrane protein 3; SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network; Belongs to the synaptobrevin family. | 0.996 |
Stx16 | Vamp4 | ENSMUSP00000085218 | ENSMUSP00000121977 | Syntaxin-16; SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network; Belongs to the syntaxin family. | Vesicle-associated membrane protein 4; Involved in the pathway that functions to remove an inhibitor (probably synaptotagmin-4) of calcium-triggered exocytosis during the maturation of secretory granules. May be a marker for this sorting pathway that is critical for remodeling the secretory response of granule (By similarity); Belongs to the synaptobrevin family. | 0.999 |
Stx16 | Vps45 | ENSMUSP00000085218 | ENSMUSP00000015891 | Syntaxin-16; SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network; Belongs to the syntaxin family. | Vacuolar protein sorting-associated protein 45; May play a role in vesicle-mediated protein trafficking from the Golgi stack through the trans-Golgi network. | 0.995 |
Stx16 | Vps54 | ENSMUSP00000085218 | ENSMUSP00000006221 | Syntaxin-16; SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network; Belongs to the syntaxin family. | Vacuolar protein sorting-associated protein 54; Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD. Within the GARP complex, required to tether the complex to the TGN. Not involved in endocytic recycling. | 0.956 |
Stx16 | Vti1a | ENSMUSP00000085218 | ENSMUSP00000093644 | Syntaxin-16; SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network; Belongs to the syntaxin family. | Vesicle transport through interaction with t-SNAREs homolog 1A; V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. Involved in vesicular transport from the late endosomes to the trans-Golgi network. Along with VAMP7, involved in an non-conventional RAB1-dependent traffic route to the cell surface used by KCNIP1 and KCND2. May be concerned with increased secretion of cytokines associated with ce [...] | 0.999 |
Stx16 | Vti1b | ENSMUSP00000085218 | ENSMUSP00000057462 | Syntaxin-16; SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network; Belongs to the syntaxin family. | Vesicle transport through interaction with t-SNAREs homolog 1B; V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. | 0.988 |
Stx16 | Ykt6 | ENSMUSP00000085218 | ENSMUSP00000002818 | Syntaxin-16; SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network; Belongs to the syntaxin family. | Synaptobrevin homolog YKT6; Vesicular soluble NSF attachment protein receptor (v-SNARE) mediating vesicle docking and fusion to a specific acceptor cellular compartment. Functions in endoplasmic reticulum to Golgi transport; as part of a SNARE complex composed of GOSR1, GOSR2 and STX5. Functions in early/recycling endosome to TGN transport; as part of a SNARE complex composed of BET1L, GOSR1 and STX5. Has a S-palmitoyl transferase activity; Belongs to the synaptobrevin family. | 0.997 |
Stx6 | Cog8 | ENSMUSP00000027743 | ENSMUSP00000093173 | Syntaxin-6; Involved in intracellular vesicle trafficking; Belongs to the syntaxin family. | Conserved oligomeric Golgi complex subunit 8; Required for normal Golgi function. | 0.873 |
Stx6 | Stx16 | ENSMUSP00000027743 | ENSMUSP00000085218 | Syntaxin-6; Involved in intracellular vesicle trafficking; Belongs to the syntaxin family. | Syntaxin-16; SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network; Belongs to the syntaxin family. | 0.999 |