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Prl7a1 Prl7a1 Prl3d1 Prl3d1 Prl3c1 Prl3c1 Prl4a1 Prl4a1 Pla2g2f Pla2g2f Tpbpa Tpbpa Prlr Prlr Tpbpb Tpbpb Oxt Oxt Prl2b1 Prl2b1 Prl8a9 Prl8a9
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Prl7a1Prolactin-7A1; Belongs to the somatotropin/prolactin family. (266 aa)    
Predicted Functional Partners:
Prl3d1
Prolactin-3D1; Belongs to the somatotropin/prolactin family.
  
  
0.849
Prl3c1
Prolactin-3C1; Belongs to the somatotropin/prolactin family.
  
  
 0.778
Prl4a1
Prolactin-4A1.
  
  
0.634
Pla2g2f
Group IIF secretory phospholipase A2; May play a role in lipid mediator production in inflammatory conditions, by providing arachidonic acid to downstream cyclooxygenases and lipoxygenases. Phospholipase A2, which catalyzes the calcium- dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides. Hydrolyzes phosphatidylethanolamine more efficiently than phosphatidylcholine, with only a modest preference for arachidonic acid versus linoelic acid at the sn-2 position. Comparable activity toward 1-palmitoyl-2-oleoyl-phosphatidylserine vesicles to that toward 1-palmitoyl-2-oleoyl-p [...]
      
 0.604
Tpbpa
Trophoblast-specific protein alpha; It may be a growth factor/hormone, perhaps involved in interaction between the maternal and fetal systems in maintenance of pregnancy.
   
  
 0.584
Prlr
Prolactin receptor; This is a receptor for the anterior pituitary hormone prolactin.
    
 
 0.572
Tpbpb
Trophoblast-specific protein beta.
   
  
 0.549
Oxt
Oxytocin-neurophysin 1; Neurophysin 1 specifically binds oxytocin.
      
 0.538
Prl2b1
Prolactin-2B1; Belongs to the somatotropin/prolactin family.
  
  
0.500
Prl8a9
Prolactin-8A9.
  
  
0.475
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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