node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Arhgap40 | Vstm2l | ENSMUSP00000130349 | ENSMUSP00000105149 | Rho GTPase-activating protein 40; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. | V-set and transmembrane domain-containing protein 2-like protein. | 0.515 |
Defb28 | Serpina1f | ENSMUSP00000112697 | ENSMUSP00000021490 | Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family. | Alpha-1-antitrypsin 1-6; Inhibitor of serine proteases. Belongs to the serpin family. | 0.652 |
Defb28 | Vstm2l | ENSMUSP00000112697 | ENSMUSP00000105149 | Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family. | V-set and transmembrane domain-containing protein 2-like protein. | 0.575 |
Defb28 | Zcchc18 | ENSMUSP00000112697 | ENSMUSP00000033804 | Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family. | Zinc finger CCHC domain-containing protein 18; Belongs to the ZCCHC12 family. | 0.579 |
Gng4 | Vstm2l | ENSMUSP00000021734 | ENSMUSP00000105149 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | V-set and transmembrane domain-containing protein 2-like protein. | 0.514 |
Igfbp3 | Vstm2l | ENSMUSP00000020702 | ENSMUSP00000105149 | Insulin-like growth factor-binding protein 3; IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Also exhibits IGF-independent antiproliferative and apoptotic effects mediated by its receptor TMEM219/IGFBP-3R. | V-set and transmembrane domain-containing protein 2-like protein. | 0.549 |
Jak2 | Vstm2l | ENSMUSP00000064394 | ENSMUSP00000105149 | Tyrosine-protein kinase JAK2; Non-receptor tyrosine kinase involved in various processes such as cell growth, development, differentiation or histone modifications. Mediates essential signaling events in both innate and adaptive immunity. In the cytoplasm, plays a pivotal role in signal transduction via its association with type I receptors such as growth hormone (GHR), prolactin (PRLR), leptin (LEPR), erythropoietin (EPOR), thrombopoietin (THPO); or type II receptors including IFN-alpha, IFN- beta, IFN-gamma and multiple interleukins. Following ligand-binding to cell surface receptors [...] | V-set and transmembrane domain-containing protein 2-like protein. | 0.527 |
Secisbp2l | Vstm2l | ENSMUSP00000055772 | ENSMUSP00000105149 | Selenocysteine insertion sequence-binding protein 2-like; Binds SECIS (Sec insertion sequence) elements present on selenocysteine (Sec) protein mRNAs, but does not promote Sec incorporation into selenoproteins. | V-set and transmembrane domain-containing protein 2-like protein. | 0.481 |
Serpina1f | Defb28 | ENSMUSP00000021490 | ENSMUSP00000112697 | Alpha-1-antitrypsin 1-6; Inhibitor of serine proteases. Belongs to the serpin family. | Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family. | 0.652 |
Serpina1f | Vstm2l | ENSMUSP00000021490 | ENSMUSP00000105149 | Alpha-1-antitrypsin 1-6; Inhibitor of serine proteases. Belongs to the serpin family. | V-set and transmembrane domain-containing protein 2-like protein. | 0.478 |
Sowaha | Vstm2l | ENSMUSP00000100561 | ENSMUSP00000105149 | Ankyrin repeat domain-containing protein SOWAHA; Belongs to the SOWAH family. | V-set and transmembrane domain-containing protein 2-like protein. | 0.507 |
Trim11 | Vstm2l | ENSMUSP00000104438 | ENSMUSP00000105149 | E3 ubiquitin-protein ligase TRIM11; E3 ubiquitin-protein ligase that promotes the degradation of insoluble ubiquitinated proteins, including insoluble PAX6, poly-Gln repeat expanded HTT and poly-Ala repeat expanded ARX. Mediates PAX6 ubiquitination leading to proteasomal degradation, thereby modulating cortical neurogenesis. May also inhibit PAX6 transcriptional activity, possibly in part by preventing the binding of PAX6 to its consensus sequences. May contribute to the regulation of the intracellular level of HN (humanin) or HN-containing proteins through the proteasomal degradation [...] | V-set and transmembrane domain-containing protein 2-like protein. | 0.591 |
Vstm2l | Arhgap40 | ENSMUSP00000105149 | ENSMUSP00000130349 | V-set and transmembrane domain-containing protein 2-like protein. | Rho GTPase-activating protein 40; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. | 0.515 |
Vstm2l | Defb28 | ENSMUSP00000105149 | ENSMUSP00000112697 | V-set and transmembrane domain-containing protein 2-like protein. | Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family. | 0.575 |
Vstm2l | Gng4 | ENSMUSP00000105149 | ENSMUSP00000021734 | V-set and transmembrane domain-containing protein 2-like protein. | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | 0.514 |
Vstm2l | Igfbp3 | ENSMUSP00000105149 | ENSMUSP00000020702 | V-set and transmembrane domain-containing protein 2-like protein. | Insulin-like growth factor-binding protein 3; IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Also exhibits IGF-independent antiproliferative and apoptotic effects mediated by its receptor TMEM219/IGFBP-3R. | 0.549 |
Vstm2l | Jak2 | ENSMUSP00000105149 | ENSMUSP00000064394 | V-set and transmembrane domain-containing protein 2-like protein. | Tyrosine-protein kinase JAK2; Non-receptor tyrosine kinase involved in various processes such as cell growth, development, differentiation or histone modifications. Mediates essential signaling events in both innate and adaptive immunity. In the cytoplasm, plays a pivotal role in signal transduction via its association with type I receptors such as growth hormone (GHR), prolactin (PRLR), leptin (LEPR), erythropoietin (EPOR), thrombopoietin (THPO); or type II receptors including IFN-alpha, IFN- beta, IFN-gamma and multiple interleukins. Following ligand-binding to cell surface receptors [...] | 0.527 |
Vstm2l | Secisbp2l | ENSMUSP00000105149 | ENSMUSP00000055772 | V-set and transmembrane domain-containing protein 2-like protein. | Selenocysteine insertion sequence-binding protein 2-like; Binds SECIS (Sec insertion sequence) elements present on selenocysteine (Sec) protein mRNAs, but does not promote Sec incorporation into selenoproteins. | 0.481 |
Vstm2l | Serpina1f | ENSMUSP00000105149 | ENSMUSP00000021490 | V-set and transmembrane domain-containing protein 2-like protein. | Alpha-1-antitrypsin 1-6; Inhibitor of serine proteases. Belongs to the serpin family. | 0.478 |
Vstm2l | Sowaha | ENSMUSP00000105149 | ENSMUSP00000100561 | V-set and transmembrane domain-containing protein 2-like protein. | Ankyrin repeat domain-containing protein SOWAHA; Belongs to the SOWAH family. | 0.507 |