STRINGSTRING
Rtl4 Rtl4 Rtl6 Rtl6 Pgbd5 Pgbd5 Fancm Fancm Rtl5 Rtl5 Gin1 Gin1 Ldoc1 Ldoc1 Rtl9 Rtl9 Itgb1 Itgb1 Nynrin Nynrin Pnmal1 Pnmal1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Rtl4Retrotransposon Gag-like protein 4; Involved in cognitive function in the brain, possibly via the noradrenergic system. (304 aa)    
Predicted Functional Partners:
Rtl6
Retrotransposon Gag-like protein 6.
  
   
 0.720
Pgbd5
PiggyBac transposable element-derived protein 5; Transposase that mediates sequence-specific genomic rearrangements.
    
 
 0.684
Fancm
Fanconi anemia group M protein homolog; DNA-dependent ATPase component of the Fanconi anemia (FA) core complex. Required for the normal activation of the FA pathway, leading to monoubiquitination of the FANCI-FANCD2 complex in response to DNA damage, cellular resistance to DNA cross-linking drugs, and prevention of chromosomal breakage. In complex with CENPS and CENPX, binds double-stranded DNA (dsDNA), fork-structured DNA (fsDNA) and Holliday junction substrates. Its ATP-dependent DNA branch migration activity can process branched DNA structures such as a movable replication fork. Thi [...]
    
 
 0.679
Rtl5
Retrotransposon Gag-like protein 5.
      
 0.677
Gin1
Gypsy retrotransposon integrase-like protein 1.
      
 0.657
Ldoc1
Protein LDOC1; May have an important role in the development and/or progression of some cancers.
      
 0.605
Rtl9
Retrotransposon Gag-like protein 9.
      
 0.605
Itgb1
Integrin beta-1; Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-2 recognize the proline-hydroxylated sequence G-F-P-G- E-R in collagen. Integrins alpha-2/beta-1, alpha-3/beta-1, alpha- 4/beta-1, alpha-5/beta-1, alpha-8/beta-1, alpha-10/beta-1, alpha- 11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Alpha- 4/beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin [...]
      
 0.604
Nynrin
Protein NYNRIN.
    
 
 0.600
Pnmal1
Paraneoplastic antigen-like protein 8A; Belongs to the PNMA family.
      
 0.590
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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