node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Cs | Csl | ENSMUSP00000005826 | ENSMUSP00000052373 | Citrate synthase, mitochondrial; Belongs to the citrate synthase family. | Citrate synthase; Belongs to the citrate synthase family. | 0.906 |
Cs | Idh1 | ENSMUSP00000005826 | ENSMUSP00000095316 | Citrate synthase, mitochondrial; Belongs to the citrate synthase family. | Isocitrate dehydrogenase [NADP] cytoplasmic; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | 0.937 |
Cs | Idh2 | ENSMUSP00000005826 | ENSMUSP00000103007 | Citrate synthase, mitochondrial; Belongs to the citrate synthase family. | Isocitrate dehydrogenase [NADP], mitochondrial; Plays a role in intermediary metabolism and energy production. It may tightly associate or interact with the pyruvate dehydrogenase complex; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | 0.942 |
Cs | Mdh1b | ENSMUSP00000005826 | ENSMUSP00000109728 | Citrate synthase, mitochondrial; Belongs to the citrate synthase family. | Putative malate dehydrogenase 1B; Belongs to the LDH/MDH superfamily. MDH type 2 family. | 0.642 |
Cs | Pklr | ENSMUSP00000005826 | ENSMUSP00000035417 | Citrate synthase, mitochondrial; Belongs to the citrate synthase family. | Pyruvate kinase PKLR; Plays a key role in glycolysis. | 0.423 |
Cs | Suclg1 | ENSMUSP00000005826 | ENSMUSP00000065113 | Citrate synthase, mitochondrial; Belongs to the citrate synthase family. | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. | 0.897 |
Csl | Cs | ENSMUSP00000052373 | ENSMUSP00000005826 | Citrate synthase; Belongs to the citrate synthase family. | Citrate synthase, mitochondrial; Belongs to the citrate synthase family. | 0.906 |
Csl | Idh1 | ENSMUSP00000052373 | ENSMUSP00000095316 | Citrate synthase; Belongs to the citrate synthase family. | Isocitrate dehydrogenase [NADP] cytoplasmic; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | 0.936 |
Csl | Idh2 | ENSMUSP00000052373 | ENSMUSP00000103007 | Citrate synthase; Belongs to the citrate synthase family. | Isocitrate dehydrogenase [NADP], mitochondrial; Plays a role in intermediary metabolism and energy production. It may tightly associate or interact with the pyruvate dehydrogenase complex; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | 0.939 |
Csl | Mdh1b | ENSMUSP00000052373 | ENSMUSP00000109728 | Citrate synthase; Belongs to the citrate synthase family. | Putative malate dehydrogenase 1B; Belongs to the LDH/MDH superfamily. MDH type 2 family. | 0.642 |
Csl | Pklr | ENSMUSP00000052373 | ENSMUSP00000035417 | Citrate synthase; Belongs to the citrate synthase family. | Pyruvate kinase PKLR; Plays a key role in glycolysis. | 0.430 |
Csl | Suclg1 | ENSMUSP00000052373 | ENSMUSP00000065113 | Citrate synthase; Belongs to the citrate synthase family. | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. | 0.842 |
Dynlrb2 | Eno4 | ENSMUSP00000077301 | ENSMUSP00000144272 | Dynein light chain roadblock-type 2; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules; Belongs to the GAMAD family. | Enolase 4; Required for sperm motility, function and male fertility. May be involved in the normal assembly of the sperm fibrous sheath and provides most of the enolase activity in sperm. | 0.504 |
Dynlrb2 | Mdh1b | ENSMUSP00000077301 | ENSMUSP00000109728 | Dynein light chain roadblock-type 2; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules; Belongs to the GAMAD family. | Putative malate dehydrogenase 1B; Belongs to the LDH/MDH superfamily. MDH type 2 family. | 0.609 |
Dynlrb2 | Nme5 | ENSMUSP00000077301 | ENSMUSP00000078269 | Dynein light chain roadblock-type 2; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules; Belongs to the GAMAD family. | Nucleoside diphosphate kinase homolog 5; Does not seem to have NDK kinase activity. Confers protection from cell death by Bax and alters the cellular levels of several antioxidant enzymes including Gpx5. May play a role in spermiogenesis by increasing the ability of late-stage spermatids to eliminate reactive oxygen species. | 0.659 |
Eno4 | Dynlrb2 | ENSMUSP00000144272 | ENSMUSP00000077301 | Enolase 4; Required for sperm motility, function and male fertility. May be involved in the normal assembly of the sperm fibrous sheath and provides most of the enolase activity in sperm. | Dynein light chain roadblock-type 2; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules; Belongs to the GAMAD family. | 0.504 |
Eno4 | Mdh1b | ENSMUSP00000144272 | ENSMUSP00000109728 | Enolase 4; Required for sperm motility, function and male fertility. May be involved in the normal assembly of the sperm fibrous sheath and provides most of the enolase activity in sperm. | Putative malate dehydrogenase 1B; Belongs to the LDH/MDH superfamily. MDH type 2 family. | 0.668 |
Eno4 | Nme5 | ENSMUSP00000144272 | ENSMUSP00000078269 | Enolase 4; Required for sperm motility, function and male fertility. May be involved in the normal assembly of the sperm fibrous sheath and provides most of the enolase activity in sperm. | Nucleoside diphosphate kinase homolog 5; Does not seem to have NDK kinase activity. Confers protection from cell death by Bax and alters the cellular levels of several antioxidant enzymes including Gpx5. May play a role in spermiogenesis by increasing the ability of late-stage spermatids to eliminate reactive oxygen species. | 0.404 |
Eno4 | Pklr | ENSMUSP00000144272 | ENSMUSP00000035417 | Enolase 4; Required for sperm motility, function and male fertility. May be involved in the normal assembly of the sperm fibrous sheath and provides most of the enolase activity in sperm. | Pyruvate kinase PKLR; Plays a key role in glycolysis. | 0.968 |
Eno4 | Suclg1 | ENSMUSP00000144272 | ENSMUSP00000065113 | Enolase 4; Required for sperm motility, function and male fertility. May be involved in the normal assembly of the sperm fibrous sheath and provides most of the enolase activity in sperm. | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. | 0.447 |