STRINGSTRING
H2ac6 H2ac6 H4c4 H4c4 H4c8 H4c8 H4c11 H4c11 H4c1 H4c1 H4c3 H4c3 H4c6 H4c6 H4c9 H4c9 Hist1h4n Hist1h4n H4c12 H4c12 H4c14 H4c14
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
H2ac6H2A clustered histone 6. (130 aa)    
Predicted Functional Partners:
H4c4
H4 clustered histone 4.
 
 
 0.994
H4c8
H4 clustered histone 8.
 
 
 0.994
H4c11
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
 
 
 0.993
H4c1
H4 clustered histone 1.
 
 
 0.993
H4c3
H4 clustered histone 3.
 
 
 0.993
H4c6
H4 clustered histone 6.
 
 
 0.993
H4c9
H4 clustered histone 9.
 
 
 0.993
Hist1h4n
Histone cluster 1, H4n.
 
 
 0.993
H4c12
H4 clustered histone 12.
 
 
 0.993
H4c14
H4 clustered histone 14.
 
 
 0.993
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.