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Gm38394 Gm38394 Zc3h11a-2 Zc3h11a-2 Zc3h11a Zc3h11a Gm5294 Gm5294 Igf2 Igf2 Lrrc61 Lrrc61 Zfp628 Zfp628 Zbed3 Zbed3 Ankrd7 Ankrd7 Zbtb38 Zbtb38 9130008F23Rik 9130008F23Rik
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
Gm38394Zinc finger BED domain-containing protein 6; Transcriptional repressor which binds to the consensus sequence 5'-GCTCGC-3' and represses transcription of IGF2. May also regulate expression of other target genes containing the binding site. (980 aa)    
Predicted Functional Partners:
Zc3h11a-2
Zinc finger CCCH type containing 11A.
      
 0.733
Zc3h11a
Zinc finger CCCH domain-containing protein 11A; Involved in nuclear mRNA export; probably mediated by association with the TREX complex.
      
 0.732
Gm5294
Predicted gene 5294.
    
 
 0.709
Igf2
Insulin-like growth factor II; The insulin-like growth factors possess growth-promoting activity (Probable). Major fetal growth hormone in mammals. Plays a key role in regulating fetoplacental development (Probable). IGF-II is influenced by placental lactogen (Probable). Also involved in tissue differentiation (Probable). Positively regulates myogenic transcription factor MYOD1 function by facilitating the recruitment of transcriptional coactivators, thereby controlling muscle terminal differentiation. In adults, involved in glucose metabolism in adipose tissue, skeletal muscle and liv [...]
      
 0.680
Lrrc61
Leucine-rich repeat-containing protein 61.
   
 
 0.652
Zfp628
Zinc finger protein 628; Transcription activator. Binds DNA on GT-box consensus sequence 5'-TTGGTT-3'.
   
  
 0.507
Zbed3
Zinc finger BED domain-containing protein 3; Acts as a positive regulator in the activation of the canonical Wnt/beta-catenin signaling pathway by stabilizing cytoplasmic beta-catenin. Involved in transcription activation of Wnt target gene expression.
      
 0.484
Ankrd7
Ankyrin repeat domain-containing protein 7.
    
 
 0.467
Zbtb38
CtBP-interacting BTB zinc finger protein.
      
 0.442
9130008F23Rik
RIKEN cDNA 9130008F23 gene.
      
 0.440
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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