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Abcf1 Abcf1 Rpl11 Rpl11 Gcn1 Gcn1 Rps23 Rps23 Rpl10a Rpl10a Rps29 Rps29 ENSRNOP00000040703 ENSRNOP00000040703 ENSRNOP00000043270 ENSRNOP00000043270 LOC108350501 LOC108350501 Abce1 Abce1 LOC100360117 LOC100360117
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Abcf1ATP-binding cassette sub-family F member 1; Required for efficient Cap- and IRES-mediated mRNA translation initiation. Not involved in the ribosome biogenesis (By similarity). (839 aa)    
Predicted Functional Partners:
Rpl11
60S ribosomal protein L11; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through [...]
   
 0.901
Gcn1
GCN1 activator of EIF2AK4.
   
 
 0.889
Rps23
40S ribosomal protein S23; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through [...]
  
 0.876
Rpl10a
60S ribosomal protein L10a; Component of the large ribosomal subunit. Belongs to the universal ribosomal protein uL1 family.
   
 0.863
Rps29
40S ribosomal protein S29.
   
  0.859
ENSRNOP00000040703
40S ribosomal protein S29.
   
  0.859
ENSRNOP00000043270
40S ribosomal protein S29.
   
  0.859
LOC108350501
Ribosomal protein S29.
   
  0.859
Abce1
ATP-binding cassette, sub-family E (OABP), member 1.
   
 
 0.855
LOC100360117
60S ribosomal protein L8; Component of the large ribosomal subunit. Belongs to the universal ribosomal protein uL2 family.
   
  0.838
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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