node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Bpifb1 | Muc5b | ENSRNOP00000052209 | ENSRNOP00000036806 | BPI fold-containing family B member 1; May play a role in innate immunity in mouth, nose and lungs. Binds bacterial lipopolysaccharide (LPS) and modulates the cellular responses to LPS (By similarity); Belongs to the BPI/LBP/Plunc superfamily. Plunc family. | Mucin 5B, oligomeric mucus/gel-forming. | 0.817 |
Bpifb1 | Tff2 | ENSRNOP00000052209 | ENSRNOP00000001537 | BPI fold-containing family B member 1; May play a role in innate immunity in mouth, nose and lungs. Binds bacterial lipopolysaccharide (LPS) and modulates the cellular responses to LPS (By similarity); Belongs to the BPI/LBP/Plunc superfamily. Plunc family. | Trefoil factor 2; Inhibits gastrointestinal motility and gastric acid secretion. Could function as a structural component of gastric mucus, possibly by stabilizing glycoproteins in the mucus gel through interactions with carbohydrate side chains. | 0.586 |
Cblif | Gast | ENSRNOP00000028507 | ENSRNOP00000019863 | Cobalamin binding intrinsic factor; Promotes absorption of the essential vitamin cobalamin (Cbl) in the ileum. After interaction with CUBN, the CBLIF-cobalamin complex is internalized via receptor-mediated endocytosis (By similarity). | Big gastrin; Gastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine. | 0.562 |
Cblif | Gkn3 | ENSRNOP00000028507 | ENSRNOP00000054164 | Cobalamin binding intrinsic factor; Promotes absorption of the essential vitamin cobalamin (Cbl) in the ileum. After interaction with CUBN, the CBLIF-cobalamin complex is internalized via receptor-mediated endocytosis (By similarity). | Gastrokine 3. | 0.574 |
Cblif | Muc6 | ENSRNOP00000028507 | ENSRNOP00000072558 | Cobalamin binding intrinsic factor; Promotes absorption of the essential vitamin cobalamin (Cbl) in the ileum. After interaction with CUBN, the CBLIF-cobalamin complex is internalized via receptor-mediated endocytosis (By similarity). | Mucin 6, oligomeric mucus/gel-forming. | 0.641 |
Cblif | Pgc | ENSRNOP00000028507 | ENSRNOP00000019650 | Cobalamin binding intrinsic factor; Promotes absorption of the essential vitamin cobalamin (Cbl) in the ileum. After interaction with CUBN, the CBLIF-cobalamin complex is internalized via receptor-mediated endocytosis (By similarity). | Gastricsin; Hydrolyzes a variety of proteins. | 0.639 |
Cblif | Tff2 | ENSRNOP00000028507 | ENSRNOP00000001537 | Cobalamin binding intrinsic factor; Promotes absorption of the essential vitamin cobalamin (Cbl) in the ileum. After interaction with CUBN, the CBLIF-cobalamin complex is internalized via receptor-mediated endocytosis (By similarity). | Trefoil factor 2; Inhibits gastrointestinal motility and gastric acid secretion. Could function as a structural component of gastric mucus, possibly by stabilizing glycoproteins in the mucus gel through interactions with carbohydrate side chains. | 0.713 |
Gast | Cblif | ENSRNOP00000019863 | ENSRNOP00000028507 | Big gastrin; Gastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine. | Cobalamin binding intrinsic factor; Promotes absorption of the essential vitamin cobalamin (Cbl) in the ileum. After interaction with CUBN, the CBLIF-cobalamin complex is internalized via receptor-mediated endocytosis (By similarity). | 0.562 |
Gast | Muc6 | ENSRNOP00000019863 | ENSRNOP00000072558 | Big gastrin; Gastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine. | Mucin 6, oligomeric mucus/gel-forming. | 0.566 |
Gast | Pgc | ENSRNOP00000019863 | ENSRNOP00000019650 | Big gastrin; Gastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine. | Gastricsin; Hydrolyzes a variety of proteins. | 0.516 |
Gast | Tff2 | ENSRNOP00000019863 | ENSRNOP00000001537 | Big gastrin; Gastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine. | Trefoil factor 2; Inhibits gastrointestinal motility and gastric acid secretion. Could function as a structural component of gastric mucus, possibly by stabilizing glycoproteins in the mucus gel through interactions with carbohydrate side chains. | 0.757 |
Gkn3 | Cblif | ENSRNOP00000054164 | ENSRNOP00000028507 | Gastrokine 3. | Cobalamin binding intrinsic factor; Promotes absorption of the essential vitamin cobalamin (Cbl) in the ileum. After interaction with CUBN, the CBLIF-cobalamin complex is internalized via receptor-mediated endocytosis (By similarity). | 0.574 |
Gkn3 | Muc6 | ENSRNOP00000054164 | ENSRNOP00000072558 | Gastrokine 3. | Mucin 6, oligomeric mucus/gel-forming. | 0.564 |
Gkn3 | Tff2 | ENSRNOP00000054164 | ENSRNOP00000001537 | Gastrokine 3. | Trefoil factor 2; Inhibits gastrointestinal motility and gastric acid secretion. Could function as a structural component of gastric mucus, possibly by stabilizing glycoproteins in the mucus gel through interactions with carbohydrate side chains. | 0.615 |
Gp2 | Tff2 | ENSRNOP00000069047 | ENSRNOP00000001537 | Pancreatic secretory granule membrane major glycoprotein GP2. | Trefoil factor 2; Inhibits gastrointestinal motility and gastric acid secretion. Could function as a structural component of gastric mucus, possibly by stabilizing glycoproteins in the mucus gel through interactions with carbohydrate side chains. | 0.609 |
Mep1a | Tff2 | ENSRNOP00000014791 | ENSRNOP00000001537 | Meprin A subunit alpha. | Trefoil factor 2; Inhibits gastrointestinal motility and gastric acid secretion. Could function as a structural component of gastric mucus, possibly by stabilizing glycoproteins in the mucus gel through interactions with carbohydrate side chains. | 0.608 |
Muc13 | Muc5b | ENSRNOP00000002444 | ENSRNOP00000036806 | Mucin-13; Epithelial and hemopoietic transmembrane mucin that may play a role in cell signaling. | Mucin 5B, oligomeric mucus/gel-forming. | 0.897 |
Muc13 | Muc6 | ENSRNOP00000002444 | ENSRNOP00000072558 | Mucin-13; Epithelial and hemopoietic transmembrane mucin that may play a role in cell signaling. | Mucin 6, oligomeric mucus/gel-forming. | 0.905 |
Muc13 | Tff2 | ENSRNOP00000002444 | ENSRNOP00000001537 | Mucin-13; Epithelial and hemopoietic transmembrane mucin that may play a role in cell signaling. | Trefoil factor 2; Inhibits gastrointestinal motility and gastric acid secretion. Could function as a structural component of gastric mucus, possibly by stabilizing glycoproteins in the mucus gel through interactions with carbohydrate side chains. | 0.575 |
Muc5b | Bpifb1 | ENSRNOP00000036806 | ENSRNOP00000052209 | Mucin 5B, oligomeric mucus/gel-forming. | BPI fold-containing family B member 1; May play a role in innate immunity in mouth, nose and lungs. Binds bacterial lipopolysaccharide (LPS) and modulates the cellular responses to LPS (By similarity); Belongs to the BPI/LBP/Plunc superfamily. Plunc family. | 0.817 |