node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Actr5 | Rnf34 | ENSRNOP00000036100 | ENSRNOP00000001799 | Actin-related protein 5; Belongs to the actin family. | E3 ubiquitin-protein ligase RNF34; E3 ubiquitin-protein ligase that regulates several biological processes through the ubiquitin-mediated proteasomal degradation of various target proteins. Ubiquitinates the caspases CASP8 and CASP10, promoting their proteasomal degradation, to negatively regulate cell death downstream of death domain receptors in the extrinsic pathway of apoptosis. May mediate 'Lys-48'-linked polyubiquitination of RIPK1 and its subsequent proteasomal degradation thereby indirectly regulating the tumor necrosis factor-mediated signaling pathway. Negatively regulates p5 [...] | 0.626 |
Asb6 | Klhl42 | ENSRNOP00000031019 | ENSRNOP00000002523 | Ankyrin repeat and SOCS box-containing 6. | Similar to C230080I20Rik protein (Predicted). | 0.649 |
Asb6 | Rnf34 | ENSRNOP00000031019 | ENSRNOP00000001799 | Ankyrin repeat and SOCS box-containing 6. | E3 ubiquitin-protein ligase RNF34; E3 ubiquitin-protein ligase that regulates several biological processes through the ubiquitin-mediated proteasomal degradation of various target proteins. Ubiquitinates the caspases CASP8 and CASP10, promoting their proteasomal degradation, to negatively regulate cell death downstream of death domain receptors in the extrinsic pathway of apoptosis. May mediate 'Lys-48'-linked polyubiquitination of RIPK1 and its subsequent proteasomal degradation thereby indirectly regulating the tumor necrosis factor-mediated signaling pathway. Negatively regulates p5 [...] | 0.576 |
Asb6 | Trim37 | ENSRNOP00000031019 | ENSRNOP00000008299 | Ankyrin repeat and SOCS box-containing 6. | Tripartite motif protein 37 (Predicted). | 0.573 |
D3ZD02_RAT | Rnf34 | ENSRNOP00000048019 | ENSRNOP00000001799 | 60S ribosomal protein L13; Belongs to the eukaryotic ribosomal protein eL13 family. | E3 ubiquitin-protein ligase RNF34; E3 ubiquitin-protein ligase that regulates several biological processes through the ubiquitin-mediated proteasomal degradation of various target proteins. Ubiquitinates the caspases CASP8 and CASP10, promoting their proteasomal degradation, to negatively regulate cell death downstream of death domain receptors in the extrinsic pathway of apoptosis. May mediate 'Lys-48'-linked polyubiquitination of RIPK1 and its subsequent proteasomal degradation thereby indirectly regulating the tumor necrosis factor-mediated signaling pathway. Negatively regulates p5 [...] | 0.497 |
D3ZD02_RAT | Rps27a | ENSRNOP00000048019 | ENSRNOP00000005872 | 60S ribosomal protein L13; Belongs to the eukaryotic ribosomal protein eL13 family. | Ubiquitin-40S ribosomal protein S27a; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be i [...] | 0.709 |
D3ZD02_RAT | Uba52 | ENSRNOP00000048019 | ENSRNOP00000027073 | 60S ribosomal protein L13; Belongs to the eukaryotic ribosomal protein eL13 family. | Ubiquitin-60S ribosomal protein L40; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be in [...] | 0.875 |
D3ZD02_RAT | Ubc | ENSRNOP00000048019 | ENSRNOP00000074688 | 60S ribosomal protein L13; Belongs to the eukaryotic ribosomal protein eL13 family. | Ubiquitin-related; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repa [...] | 0.442 |
Klhl42 | Asb6 | ENSRNOP00000002523 | ENSRNOP00000031019 | Similar to C230080I20Rik protein (Predicted). | Ankyrin repeat and SOCS box-containing 6. | 0.649 |
Klhl42 | Rnf34 | ENSRNOP00000002523 | ENSRNOP00000001799 | Similar to C230080I20Rik protein (Predicted). | E3 ubiquitin-protein ligase RNF34; E3 ubiquitin-protein ligase that regulates several biological processes through the ubiquitin-mediated proteasomal degradation of various target proteins. Ubiquitinates the caspases CASP8 and CASP10, promoting their proteasomal degradation, to negatively regulate cell death downstream of death domain receptors in the extrinsic pathway of apoptosis. May mediate 'Lys-48'-linked polyubiquitination of RIPK1 and its subsequent proteasomal degradation thereby indirectly regulating the tumor necrosis factor-mediated signaling pathway. Negatively regulates p5 [...] | 0.651 |
Klhl42 | Trim37 | ENSRNOP00000002523 | ENSRNOP00000008299 | Similar to C230080I20Rik protein (Predicted). | Tripartite motif protein 37 (Predicted). | 0.619 |
LOC100360491 | Rnf34 | ENSRNOP00000064082 | ENSRNOP00000001799 | 60S ribosomal protein L13; Belongs to the eukaryotic ribosomal protein eL13 family. | E3 ubiquitin-protein ligase RNF34; E3 ubiquitin-protein ligase that regulates several biological processes through the ubiquitin-mediated proteasomal degradation of various target proteins. Ubiquitinates the caspases CASP8 and CASP10, promoting their proteasomal degradation, to negatively regulate cell death downstream of death domain receptors in the extrinsic pathway of apoptosis. May mediate 'Lys-48'-linked polyubiquitination of RIPK1 and its subsequent proteasomal degradation thereby indirectly regulating the tumor necrosis factor-mediated signaling pathway. Negatively regulates p5 [...] | 0.497 |
LOC100360491 | Rps27a | ENSRNOP00000064082 | ENSRNOP00000005872 | 60S ribosomal protein L13; Belongs to the eukaryotic ribosomal protein eL13 family. | Ubiquitin-40S ribosomal protein S27a; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be i [...] | 0.709 |
LOC100360491 | Uba52 | ENSRNOP00000064082 | ENSRNOP00000027073 | 60S ribosomal protein L13; Belongs to the eukaryotic ribosomal protein eL13 family. | Ubiquitin-60S ribosomal protein L40; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be in [...] | 0.875 |
LOC100360491 | Ubc | ENSRNOP00000064082 | ENSRNOP00000074688 | 60S ribosomal protein L13; Belongs to the eukaryotic ribosomal protein eL13 family. | Ubiquitin-related; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repa [...] | 0.442 |
LOC100361259 | Rnf34 | ENSRNOP00000063355 | ENSRNOP00000001799 | 60S ribosomal protein L13; Belongs to the eukaryotic ribosomal protein eL13 family. | E3 ubiquitin-protein ligase RNF34; E3 ubiquitin-protein ligase that regulates several biological processes through the ubiquitin-mediated proteasomal degradation of various target proteins. Ubiquitinates the caspases CASP8 and CASP10, promoting their proteasomal degradation, to negatively regulate cell death downstream of death domain receptors in the extrinsic pathway of apoptosis. May mediate 'Lys-48'-linked polyubiquitination of RIPK1 and its subsequent proteasomal degradation thereby indirectly regulating the tumor necrosis factor-mediated signaling pathway. Negatively regulates p5 [...] | 0.497 |
LOC100361259 | Rps27a | ENSRNOP00000063355 | ENSRNOP00000005872 | 60S ribosomal protein L13; Belongs to the eukaryotic ribosomal protein eL13 family. | Ubiquitin-40S ribosomal protein S27a; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be i [...] | 0.709 |
LOC100361259 | Uba52 | ENSRNOP00000063355 | ENSRNOP00000027073 | 60S ribosomal protein L13; Belongs to the eukaryotic ribosomal protein eL13 family. | Ubiquitin-60S ribosomal protein L40; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be in [...] | 0.875 |
LOC100361259 | Ubc | ENSRNOP00000063355 | ENSRNOP00000074688 | 60S ribosomal protein L13; Belongs to the eukaryotic ribosomal protein eL13 family. | Ubiquitin-related; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repa [...] | 0.442 |
Rnf34 | Actr5 | ENSRNOP00000001799 | ENSRNOP00000036100 | E3 ubiquitin-protein ligase RNF34; E3 ubiquitin-protein ligase that regulates several biological processes through the ubiquitin-mediated proteasomal degradation of various target proteins. Ubiquitinates the caspases CASP8 and CASP10, promoting their proteasomal degradation, to negatively regulate cell death downstream of death domain receptors in the extrinsic pathway of apoptosis. May mediate 'Lys-48'-linked polyubiquitination of RIPK1 and its subsequent proteasomal degradation thereby indirectly regulating the tumor necrosis factor-mediated signaling pathway. Negatively regulates p5 [...] | Actin-related protein 5; Belongs to the actin family. | 0.626 |